04/11/2024
MSM+C proof of effectiveness for arthritis
Proof that the supplements we provide outperform medications provided by big pharma. Here are a few of the 100s of studies that can be found with a simple search with Google Scholar, proving that just one ingredient in our formula, in the amounts provided, outperform even the best medications ever produced by man. Again showing the validity of our claim that God and his creations continue to outperform man and his concoctions for the overall health and healing of the human body.
Methylsulfonylmethane (MSM): a double-blind study of its use in degenerative arthritis
RESULTS
The V.A.S. was completed by each patient at the four week and at the six week visit. Records were measured by an independent evaluator.
At the four week visit, the patients on the LIGNISULmsm, showed a 60 percent improvement on average, while at the six week V.A.S. evaluation the patients showed and 82 percent improvement in pain on average. Those on the placebo showed an improvement of 20 percent on average at four weeks and an 18 percent improvement on average at six weeks.
ABSTRACT
This preliminary simple study was performed to initially evaluate 16 patients suffering from degenerative arthritis as to the effect of using LIGNISULmsm to control their pain. Eight patients, randomly chosen, were treated with 2250 mgms of M.S.M. per day. Six patients received placebo capsules. Results indicate a better than 80 percent control of pain within six weeks of beginning the study, while only two patients showed a minimal improvement (less than 20 percent) on the placebo. Although this was only a simple preliminary study, it appears that a more intensive investigation of M.S.M. is warranted. A larger group of arthritic patients and additional measurement evaluation (such as range of motion, etc.) should be utilized in such a future study. LIGNISULmsm may offer a significant new nutritional substance for the control of arthritic pain as a safe, non-toxic method.
Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial
Results
Compared to placebo, MSM produced significant decreases in WOMAC pain and physical function impairment (P < 0.05). No notable changes were found in WOMAC stiffness and aggregated total symptoms scores. MSM also produced improvement in performing activities of daily living when compared to placebo on the SF-36 evaluation (P < 0.05).
Conclusion
MSM (3 g twice a day) improved symptoms of pain and physical function during the short intervention without major adverse events.
Toxicity of methylsulfonylmethane in rats
Acute toxicity
No mortality was observed. No adverse effects or clinical signs of toxicity were observed for any animals dosed during the study. No discernible differences in weight gain were noted between treatment groups. No gross lesions were noted in any rats on necropsy.
Subchronic toxicity
Oral administration of MSM in a dose of 1.5 g/kg/day for 90 days did not cause any mortality. No adverse effects were observed for any animals. Body weight and estimated food consumption were not affected. No hematological or blood
Conclusions
A single dose of 2 g/kg of MSM was well tolerated by both male and female rats. For either s*x, no mortality, adverse effects or clinical signs of toxicity, effects on body weight gain, or gross lesions were noted in animals given MSM.
Oral administration of 1.5 g/kg/day MSM for 90 days did not cause any adverse effects or mortality. Body weight and estimated food consumption were not affected. No hematological or clinical chemical alterations were noted. Renal histology of treated animals was…
Randomised, double-blind, parallel, placebo-controlled study of oral glucosamine, methylsulfonylmethane and their combination in osteoarthritis
Results:
Glu, MSM and their combination significantly improved signs and symptoms of osteoarthritis compared with placebo. There was a statistically significant decrease in mean (± SD) pain index from 1.74 ± 0.47 at baseline to 0.65 ± 0.71 at week 12 with Glu (p < 0.001). MSM significantly decreased the mean pain index from 1.53 ± 0.51 to 0.74 ± 0.65, and combination treatment resulted in a more significant decrease in the mean pain index (1.7 ± 0.47 to 0.36 ± 0.33; p < 0.001). After 12 weeks, the mean swelling index significantly decreased with Glu and MSM, while the decrease in swelling index with combination therapy was greater (1.43 ± 0.63 to 0.14 ± 0.35; p < 0.05) after 12 weeks. The combination produced a statistically significant decrease in the Lequesne index. All treatments were well tolerated.
Conclusion: Glu, MSM and their combination produced an analgesic and anti-inflammatory effect in osteoarthritis. Combination therapy showed better efficacy in reducing pain and swelling and in improving the functional ability of joints than the individual agents. All the treatments were well tolerated. The onset of analgesic and anti-inflammatory activity was found to be more rapid with the combination than with Glu. It can be concluded that the combination of MSM with Glu provides better and more rapid improvement in patients with osteoarthritis.
MSM+C from Herbs & More Athens NHCHerb shop Killen al and nhcherbs.com