02/07/2026
Cannabis, particularly low-dose THC and CBD, may improve cognitive function in older adults by reducing brain inflammation, boosting neurogenesis in the hippocampus, and enhancing neural connectivity. It potentially reverses age-related decline by stimulating CB1 receptors, improving memory, learning, and processing speed while preserving brain volume in key areas.
🗂️Key Mechanisms for Cognitive Improvement
📑Neuroprotection and Anti-inflammatory Effects: CBD reduces oxidative stress and neuroinflammation, which are common in aging brains and linked to neurodegenerative conditions.
📑Restoring Brain Function via Low-Dose THC: Preclinical studies suggest very low-dose THC can reverse age-related declines in cognitive performance by acting on the endocannabinoid system.
📑Improved Neural Connectivity: Cannabis use in older adults has been associated with greater functional connectivity between the hippocampus and cerebellum, areas vital for memory and learning.
📑Neurogenesis: Daily stimulation of cannabinoid receptors has been shown to increase the growth of new neurons in the hippocampus.
🗂️Impact on Cognitive Domains:
📑Memory and Processing: Studies have linked lifetime cannabis use to better performance in processing speed, attention, and working memory.
📑Neural Structure: Lifetime use has been associated with larger brain volumes in CB1-rich regions like the caudate, putamen, and hippocampus.
Cannabis, particularly low-dose THC and CBD, may improve cognitive function in older adults by reducing brain inflammation, boosting neurogenesis in the hippocampus, and enhancing neural connectivity. It potentially reverses age-related decline by stimulating CB1 receptors, improving memory, learning, and processing speed while preserving brain volume in key areas.
🗂️Key Mechanisms for Cognitive Improvement
📑Neuroprotection and Anti-inflammatory Effects: CBD reduces oxidative stress and neuroinflammation, which are common in aging brains and linked to neurodegenerative conditions.
📑Restoring Brain Function via Low-Dose THC: Preclinical studies suggest very low-dose THC can reverse age-related declines in cognitive performance by acting on the endocannabinoid system.
📑Improved Neural Connectivity: Cannabis use in older adults has been associated with greater functional connectivity between the hippocampus and cerebellum, areas vital for memory and learning.
📑Neurogenesis: Daily stimulation of cannabinoid receptors has been shown to increase the growth of new neurons in the hippocampus.
🗂️Impact on Cognitive Domains:
📑Memory and Processing: Studies have linked lifetime cannabis use to better performance in processing speed, attention, and working memory.
📑Neural Structure: Lifetime use has been associated with larger brain volumes in CB1-rich regions like the caudate, putamen, and hippocampus.
