01/05/2026
When the body does not feel safe, it cannot rest, digest, reproduce, or heal.
Chronic stress keeps the HPA axis activated and signals ongoing cortisol release.
While this response is protective in the short term, prolonged activation disrupts normal communication between the brain, adrenal glands, and other hormone systems.
👉🏼 Over time, this can contribute to sleep disruption, blood sugar instability, slowed digestion, increased inflammation, and hormonal imbalances that feel difficult to resolve.
This is why stress physiology is a foundational focus in functional medicine.
Supporting the HPA axis helps restore regulation across multiple systems rather than addressing symptoms in isolation.
This diagram breaks down how the stress response works and why prolonged stress can have such widespread effects.
📌 Save this post if stress feels like a key part of your health picture and you want to better understand what’s happening beneath the surface.
And comment any questions you have below! 💙