04/14/2026
Three recently published human NAD studies.
Same target. Completely different outcomes.
Grant et al., Frontiers in Aging Neuroscience, 2019
-750 mg IV over 6 hours.
-No sustained NAD increase.
-Rapid breakdown and clearance.
Reyna et al., Frontiers in Aging, 2026
-500 mg IV daily for 4 days.
-No meaningful improvement in NAD, CRP, glucose, or lipids.
-100% of patients treated experienced moderate to severe side effects.
This 👆is the current standard.
Now compare that to our 2026 randomized controlled trial:
“Novel Oral LNAD+ Increases Intracellular NAD and Metabolic Flux Without Elevating Circulating NAD” (RCT, 2026)
-Significant increase in intracellular NAD.
-Increased metabolic flux.
-No IV.
-No side effects.
THIS is the shift.
From forcing NAD into the bloodstream…to actually restoring it inside the cell.
If it’s not increasing NAD inside the cell, it’s just not working.
Comment “LNAD” if you want the protocol.