The Jackson Laboratory

01/03/2026

Virtual hearts, flu therapy, and more: From AI-powered research to unlocking gene function, JAX scientists are paving the way for the future of precision medicine. Here is some notable news you may have missed.

JAX is addressing the significant challenges in drug development with the CARDIOVERSE project, which utilizes AI-powered "virtual hearts" to enhance drug safety testing.

01/02/2026

✨ Did you know JAX offers free, self‑paced online MicroLessons (15 minutes) and Mini‑Courses (1–2 hours)?

👉 MicroLessons: https://education.learning.jax.org/page/online-microlessons
👉 Mini‑Courses: https://education.learning.jax.org/page/online-minicourses

01/01/2026

We know it's New Years Eve, but these aren't fireworks 🎇!

Check out this microscopy image of neural progenitor cells — multipotent, self-renewing cells in the central nervous system that generate neurons and glial cells in the 🧠.

Credit: Pera Lab at JAX

12/30/2025

New year, new era of discovery. Thank you for all of your support this year and we can’t wait to share 2026 with you. Happy New Year from all of us at The Jackson Laboratory!

12/29/2025

we took a look back at the moments that defined 2025. From researchers publishing more than 285 papers in scientific journals to helping more than 1,900 cancer patients in Maine gain access to cutting-edge cancer care, take a look back with us by watching this year's JAX Wrapped.

12/28/2025

As we head into 2026, we're sharing some of our most popular posts of 2025.

This story, published in July, about how scientists at JAX developed mouse models that survive premature death and enable pre-clinical testing of alternating hemiplegia of childhood (AHC) was our most clicked news story of the year on social media.

AHC is a devastating and sometimes fatal neurological disorder that affects about one in a million children with no treatment yet. The research comes from the JAX Rare Disease Translational Center, which focuses on bridging the gap between genetic research and clinical treatment by working closely with other scientific organizations, families, and patient foundations to drive therapies for rare diseases.

The models offer clear insights into how alternating hemiplegia of childhood progresses—and how it might be stopped.

12/27/2025

As we head into 2026, we're sharing some of our most popular posts of 2025.

This video from our JAX in Motion series showcases a major paper published this summer in Nature Medicine. The paper revealed that chronic fatigue syndrome (ME/CFS) may leave detectable biological fingerprints in the body. These previously undetectable biomarkers in gut bacteria, immune responses, and metabolism offer hope for future diagnostic tools.

Learn more: https://www.jax.org/news-and-insights/2025/july/gut-microbiome-may-predict-invisible-chronic-fatigue-syndrome-and-long-covid

12/26/2025

As we head into 2026, we're sharing some of our most popular posts of 2025. This featured image taken by the JAX Single Cell Biology Lab of was our most popular image of the year on social media. It shows a single-cell spatial transcriptomic map of the human endometrium (the inner lining of the uterus).

By examining the endometrium’s cellular and molecular landscape, JAX researchers hope to uncover how endometriosis alters tissue receptivity and impacts fertility.

12/23/2025

This new featured image from JAX shows a 3D rendering revealing the intricate interior of a human stem cell, centered around a prominent blue nucleus.

Surrounding it, the cytoplasm contains major organelles, including a branching network of mitochondria (maroon tubes) that extends throughout the cell. The rough endoplasmic reticulum lies closely against one side of the nuclear envelope, adjacent to a pink Golgi apparatus composed of curved cisternae (bottom right). Free ribosomes are dispersed across the cytosol alongside small vesicles such as lysosomes (pink spheres), peroxisomes, and endosomes. A far-reaching network of microtubules (thin pink lines) spans the cytoplasm, forming a supportive and organizing scaffold for cellular structure and transport.

JAX brings gold-standard precision to human induced pluripotent stem cell (hiPSC) research. JAX offers a catalog of more than 650 engineered hiPSC lines on the well-established KOLF2.1J background. These models enable robust and reproducible disease modeling, functional genomics, and scalable early drug discovery workflows.

Learn more: https://www.jax.org/news-and-insights/2025/december/understanding-the-structure-of-a-stem-cell

🖥️ : The 3D polygonal model was created in Autodesk Maya and Maxon ZBrush, using custom scripts and referencing volume image datasets from The Jackson Laboratory, Allen Institute for Cell Science, and other leading scientific institutions.

12/23/2025

JAX's new CARDIOVERSE project combines AI, stem cells, and genetic variation to predict drug safety before human trials.

JAX researchers will leverage mice and human stem cells that model the range of genetic backgrounds found in people and combine that with advanced artificial intelligence to create computational “digital twins” of the human heart. By building virtual, beating hearts, our scientists aim to dramatically reduce the need for large-animal studies, streamline FDA approval, and ensure safer, faster delivery of new therapies to patients.

Explore this infographic to learn more about the project, or visit: go.jax.org/cardioverse

12/19/2025

At a packed event on Wednesday in Manhattan, we officially "tied the ribbon" with The New York Stem Cell Foundation Research Institute. JAX and NYSCF officials, local politicians, and supporters came together to celebrate the symbolic joining of our two organizations — and the start of a new era in biomedical discovery.

Get the full story: go.jax.org/ribbon-tying

12/18/2025

Celebrating the biggest accomplishments from 2025, JAX Wrapped is here!

We're taking a look back at the moments that defined our year, from our acquisition of the New York Stem Cell Foundation to reaching more than 8,500 learners across the globe.

Join us in commemorating a fantastic year at JAX — what were some of your favorite highlights from the year?