The Jackson Laboratory

The Jackson Laboratory Est. 1929, JAX is a non-profit scientific research institute specializing in genetics, genomics & mouse models of disease. www.jax.org Cancer. Diabetes.

Alzheimer’s. Heart Disease. Parkinson’s. The Jackson Laboratory (JAX) leads the search to cure diseases rooted in our DNA. We are an NCI-designated cancer center and an independent 501(c)3 nonprofit organization with over 90 years of experience in genetics and genomics research. JAX blends the brightest minds with state-of-the-art resources to accelerate discovery. Areas of Discovery (>60 Principal Investigators, >250 Ph.D.s, M.D.s, and D.V.M.s):
• Cancer: We are a National Cancer Institute designated Cancer Center focusing on cancer initiation, progression, prevention and therapies.
• Developmental/reproductive biology: birth defects, Down syndrome, osteoporosis, fertility
• Immunology: HIV-AIDS, anemia, autoimmunity, cancer immunology, immune disorders, lupus, transplant rejection
• Metabolic diseases: atherosclerosis, cardiovascular disease, diabetes, high blood pressure, obesity, microbiome
• Neurobiology: blindness, Parkinson’s, Alzheimer’s, deafness, epilepsy, glaucoma, macular degeneration, neurodegenerative diseases
• Neurobehavioral disorders: autism, addiction, depression

Supporting Global Research:
• The JAX Mouse Repository and Scientific Services are among the premier resources available for biomedical research. Committed to Education:
• Summer Student Program (undergrad & high school)
• Teaching the Genome Generation Short Course
• Ph.D. programs: U. Maine, Tufts University and U. Connecticut
• Courses, Conferences and Workshops

Support The Jackson Laboratory: https://www.jax.org/give-to-jax

The JAX-NYSCF Collaborative has announced a five-year strategic research collaboration with GSK focused on advancing hum...
02/18/2026

The JAX-NYSCF Collaborative has announced a five-year strategic research collaboration with GSK focused on advancing human cellular models of neurodegenerative disease, including Alzheimer’s disease.

The collaboration reflects a strategic focus that brings together human stem cell research, advanced data science tools, and large-scale research systems to help close a long-standing gap between scientific discovery and the development of new medicines. The goal is to generate disease-relevant cellular models that enable the scientific community to interrogate the underlying human biology of neurodegenerative conditions such as Alzheimer’s disease and accelerate the translation of those insights into potential therapies.

Collaboration advances next-generation, human-relevant research tools to accelerate the development of treatments for Alzheimer’s disease and other neurodegenerative conditions

Our partnerships — especially those with our generous donors — make us stronger. Read about the many ways that JAX suppo...
02/18/2026

Our partnerships — especially those with our generous donors — make us stronger. Read about the many ways that JAX supporters made a difference in 2025:
go.jax.org/impact2025

To better understand diseases that develop toward the end of life, JAX Postdoctoral Associate Lauren Kuffler looks at th...
02/17/2026

To better understand diseases that develop toward the end of life, JAX Postdoctoral Associate Lauren Kuffler looks at the beginning. Read about how she's unlocking clues to aging by studying early development:

To better understand diseases that develop toward the end of life, Lauren Kuffler looks at the beginning.

🌹 Roses are red, 💙 violets are blue, 💻 virtual hearts are important for me and you. Discover how AI-powered virtual hear...
02/14/2026

🌹 Roses are red, 💙 violets are blue, 💻 virtual hearts are important for me and you. Discover how AI-powered virtual hearts are reshaping drug safety testing this Valentine's Day. go.jax.org/cardioverse

With an estimated 200 million cases worldwide, age-related macular degeneration (AMD) is the most common cause of vision...
02/13/2026

With an estimated 200 million cases worldwide, age-related macular degeneration (AMD) is the most common cause of vision loss in the aging population. JAX scientist Martin Pera is working to change the odds by engineering grafted cells that restore light-sensing cells in the eye, ultimately reversing vision loss related to AMD. Learn more:

A new gene therapy strategy underway at JAX could help reverse vision loss associated with age-related macular degeneration.

Alzheimer’s disease is the sixth leading cause of death in the U.S., yet it is still poorly understood despite its huge ...
02/11/2026

Alzheimer’s disease is the sixth leading cause of death in the U.S., yet it is still poorly understood despite its huge cost and burden. We sat down with JAX Professor Greg Carter to talk about how he is using data and computational science to connect experimental models to real human disease.

Five questions with JAX Professor Greg Carter

The appointments of three internationally recognized faculty to endowed chairs at The Jackson Laboratory will shape how ...
02/06/2026

The appointments of three internationally recognized faculty to endowed chairs at The Jackson Laboratory will shape how diseases like cancer, Alzheimer’s disease and age-related immune decline are understood, detected and treated worldwide. Read more: https://bit.ly/3Mf2Mm3

Appointments highlight the value of data science and computational tools that accelerate discoveries in human health.

🎉 🧬 Teaching the Genome Generation in action!Congrats Mr. Linders and class for completing our curriculum, a program des...
01/29/2026

🎉 🧬 Teaching the Genome Generation in action!

Congrats Mr. Linders and class for completing our curriculum, a program designed to provide high school teachers the content knowledge, teaching strategies, and resources needed to enhance student learning in genetics, genomics, and personalized medicine.

More information about our program is in the comments below.

A new stem cell–based platform developed at The Jackson Laboratory (JAX) is shedding light on one of the biggest mysteri...
01/23/2026

A new stem cell–based platform developed at The Jackson Laboratory (JAX) is shedding light on one of the biggest mysteries in genetics: Why the same disease-causing mutation can affect people in dramatically different ways—from severe symptoms to no symptoms at all.

Learn more: https://go.jax.org/stem-cells-autism

01/21/2026

When doctors diagnose a brain tumor, they often face a high-stakes mystery: Is it slow-growing and treatable or aggressive and terminal? But what if brain tumors could be more accurately diagnosed? Melissa Kelly and the JAX Advanced Precision Medicine Laboratory are changing the lives of patients through cutting-edge testing.

Learn more: https://www.jax.org/news-and-insights/2025/may/precision-brain-cancer-diagnosis

Hour Newsroom recently published an article highlighting EndoRISE, a statewide initiative in Connecticut focused on adva...
01/16/2026

Hour Newsroom recently published an article highlighting EndoRISE, a statewide initiative in Connecticut focused on advancing research, innovation, support, and education for those affected by endometriosis.

EndoRISE is striving to improve understanding of this complex and prevalent disease by expanding resources for patients, clinicians, and researchers.

The program is powered by minds and hearts from UConn Health and The Jackson Laboratory, including Elise Courtois, who co-leads the initiative and directs JAX’s Single Cell Biology Lab, and Caroline Haney, a JAX postdoctoral associate whose research centers on pain mechanisms in endometriosis. Their work, featured in the article and along with contributions from the broader JAX and UConn Health teams, is helping to build new scientific insight and deepen awareness of a condition that impacts millions.

Read it:

Despite its prevalence and complexity, the exact cause and biology of endometriosis is still not well understood.

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04609

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+12072886000

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Our Story

Cancer. Diabetes. Alzheimer’s. Heart disease. Parkinson’s... The Jackson Laboratory (JAX) leads the search to cure diseases rooted in our DNA. We are an independent 501(c)3 nonprofit organization with 90 years of experience in genetics and genomics research. In addition to 70+ research labs, we house many National Institutes of Health-funded Research Centers and have a rich curriculum of both in-person and online courses and workshops in genetics and genomics.

JAX has its mammalian genetics headquarters in Bar Harbor, Maine; a Genomic Medicine institute in Farmington, Conn.; and facilities in Sacramento, Calif., Ellsworth, Maine and Shanghai, China.

Areas of Discovery (>75 Principal Investigators, >250 Ph.D.s, M.D.s, and D.V.M.s): • Cancer: We are a National Cancer Institute (NCI)-designated Cancer Center focusing on cancer initiation, progression, prevention and therapies. • Developmental/reproductive biology: birth defects, Down syndrome, osteoporosis, fertility • Immunology: HIV-AIDS, anemia, autoimmunity, cancer immunology, immune disorders, lupus, transplant rejection • Metabolic diseases: atherosclerosis, cardiovascular disease, diabetes, high blood pressure, obesity, microbiome • Neurobiology: blindness, Parkinson’s, Alzheimer’s, deafness, epilepsy, glaucoma, macular degeneration, neurodegenerative diseases • Neurobehavioral disorders: autism, addiction, depression Supporting Global Research: • The JAX Mouse Repository and Scientific Services are among the premier resources available for biomedical research. • 2.5 million JAX® Mice are distributed annually to more than 900 institutions in 56 countries. Committed to Education: • Summer Student Program (undergrad & high school) • Teaching the Genome Generation Short Course • Ph.D. programs: U. Maine, Tufts University and U. Connecticut • Courses, Conferences and Workshops Support The Jackson Laboratory: https://www.jax.org/give-to-jax