12/16/2025
A recent Aging US study examined theobromine exposure and markers of biological aging, including epigenetic age acceleration and telomere length. Higher theobromine levels were associated with slower epigenetic aging and longer telomeres.
This does not mean eating more chocolate slows aging. It reinforces something more important - specific compounds can interact with aging biology long before disease appears.
Theobromine is associated with slower epigenetic ageing
Ramy Saad1,2 , Ricardo Costeira1 , Pamela R. MatĂas-GarcĂa3 , Sergio Villicaña1 , Christian Gieger3 , Karsten Suhre4 , Annette Peters5,6 , Gabi KastenmĂĽller7 , Ana Rodriguez-Mateos8 , Cristina Dias9 , Cristina Menni1,10,11 , Melanie Waldenberger3 , Jordana T. Bell1
https://doi.org/10.18632/aging.206344