10/20/2025
WHAT IS NAD?
NAD, also known as nicotinamide-adenine dinucleotide, is a coenzyme found naturally in the cells of the body, which plays an important role in energy production and other processes.
A coenzyme is a helper molecule that binds to an enzyme to help carry out a chemical reaction. NAD assists in processes in the mitochondria, the powerhouse of the cell, and helps "keep the gears running" in the reaction that makes ATP, or cellular energy.
"NAD is a really critical molecule involved in metabolism ... (and) making energy, which is needed for every function of the body".
HOW IT WORKS.
NAD helps hundreds of enzymes in our cells do their jobs, from energy production to mitochondrial function. "Some of those enzymes are involved in cellular repair, so helping cells that have damage due to ultraviolet (UV) radiation.
NAD also plays a crucial role in DNA repair, inflammation, cellular signaling, circadian rhythm and more.
βItβs in all our cells, helping make energy but also helping repair ourselves,β Therefore, NAD is important for the healthy aging of tissues throughout the body.
Our NAD stores start to decline around young adulthood and keep declining as we age,
βPart of that is thought to be due to the fact that we accumulate more damage over our lifespan. So all these enzymes are more active, trying to repair the damage and consuming more of the available NAD."
The total amount of NAD in our cells also decreases with cardiometabolic diseases, studies suggest.
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