01/24/2026
Arterial vs. Venous Ulcers: How to Tell the Difference
Leg wounds that fail to heal can be stressful, painful, and confusing for patients. Many people assume all leg ulcers are the same, but in reality, the cause of the ulcer determines how it should be treated. The two most common types are venous ulcers and arterial ulcers, and each requires very different medical management. Treating the wrong type—or delaying proper evaluation—can lead to serious complications.
At the Vascular Center and Vein Clinic of Southern Indiana, board-certified vascular surgeon Dr. Ricardo Vasquez has more than 20 years of experience diagnosing and treating both venous and arterial ulcers. With the only fully accredited vascular lab operated by a vascular surgeon within 100 miles, Dr. Vasquez provides immediate, in-office ultrasound testing and expert evaluation without the need for a hospital referral. This ensures patients receive accurate diagnosis and appropriate treatment right away.
What Are Venous Ulcers?
Venous ulcers are the most common type of leg ulcer and typically result from venous insufficiency—a condition in which the valves in the leg veins stop functioning properly. When these valves fail, blood pools in the lower legs, increasing pressure in the surrounding tissues. Over time, this persistent pressure causes swelling, skin discoloration, inflammation, and eventually skin breakdown.
Venous ulcers tend to appear on the inner ankle or lower leg, where swelling is most pronounced. The skin around the ulcer may appear brownish, hardened, or irritated. These ulcers often ooze fluid and may be accompanied by aching, heaviness, or chronic swelling.
Without correcting the underlying vein reflux, these ulcers tend to heal slowly or repeatedly reopen. Fortunately, modern office-based vein treatments—such as Venefit™ radiofrequency ablation or Varithena®—can significantly improve circulation and support healing.
What Are Arterial Ulcers?
Arterial ulcers, on the other hand, are caused by poor blood flow to the legs, usually from peripheral artery disease (PAD). In PAD, plaque builds up in the arteries, narrowing or blocking blood flow. Without enough oxygen and nutrients reaching the tissues, the skin can break down, especially with minor trauma.
Arterial ulcers most commonly appear on the toes, feet, or bony areas, such as the heels. The surrounding skin may feel cool, pale, or thin. Patients often experience leg pain when walking (claudication) or even at rest if circulation is severely reduced. Arterial ulcers rarely ooze fluid because blood supply is limited, and they tend to be deep, dry, and painful.
Unlike venous ulcers, arterial ulcers will not heal unless blood flow is restored. This requires prompt vascular evaluation to determine whether medical therapy, angioplasty, stenting, or other interventions are needed.
Why Proper Diagnosis Matters
Although venous and arterial ulcers can look similar to the untrained eye, treating them incorrectly can have serious consequences. For example:
- Compression therapy helps venous ulcers but can be dangerous in untreated arterial disease.
- Wound dressings alone will not correct the underlying cause of either type.
- Delayed diagnosis may increase risk of infection, tissue loss, or even amputation in severe arterial disease.
Because the treatment pathways differ so greatly, accurate diagnosis is essential—and this begins with a vascular ultrasound performed by an experienced specialist.
At Dr. Vasquez’s office, patients receive same-day evaluation using an accredited vascular ultrasound lab. This allows him to assess blood flow in both the arteries and veins, determine the exact cause of the ulcer, and recommend the appropriate treatment immediately—without hospital delays or high facility fees.
When to Seek an Evaluation
If you have a wound on your leg, ankle, foot, or toes that hasn’t healed within two weeks—or if you have increasing swelling, discoloration, pain, or skin breakdown—you should schedule an evaluation promptly. No referral is needed.
Call 812-336-6008 to schedule an appointment with Dr. Ricardo Vasquez, board-certified vascular surgeon at the Vascular Center and Vein Clinic of Southern Indiana. Early diagnosis leads to faster healing, fewer complications, and better long-term outcomes.