Clinton Health Access Initiative

05/18/2026

Latin America went from sourcing less than 1% of its vaccines regionally to 23% in five years. That's a real shift.

But building capacity and sustaining it are two different challenges.

New research from CHAI and RVMC finds that most regional manufacturers are still confined to their home markets, and government purchasing commitments remain limited, making it difficult for manufacturers to plan and invest with confidence.

As global health leaders gather in Geneva this week, we're publishing new findings on what it actually takes to make regional vaccine manufacturing sustainable — and what needs to change to get there.

https://ow.ly/HxwP50Z0lIW

05/18/2026

Southeast Asia has several vaccine manufacturers, a strong track-record of investments, and political will behind regional vaccine production. What it doesn't yet have is the market conditions to make that capacity commercially sustainable.

An estimated 60–90% of the region's manufacturing capacity sits with a single producer. Most others supply primarily to their domestic market. And different national regulatory systems make cross-border supply slow and costly, even where the capacity exists.

New research from CHAI and RVMC maps the structural risks and sets out a practical path forward. Published today as global health leaders convene at WHA.

https://ow.ly/BiV750Z0m1o

05/06/2026

🌍 Africa's health systems are at an inflection point. As global health funding declines, African governments are charting a new path: building health systems that thrive on their own resources. Today, ONE and CHAI announced a partnership to support this work. We're bringing technical expertise in health financing and political advocacy to help governments in Nigeria, Senegal, and Sierra Leone lead their own reform. Because a mother in Lagos or Freetown shouldn't have to bankrupt her family to access care. And African governments are building the systems to make that possible.
https://ow.ly/vtAk50YVaWC

05/05/2026

On this , we want to celebrate the midwives in Uganda who are saving lives — and the tools they are using to do it.

Postpartum hemorrhage — heavy bleeding after childbirth — is one of the leading causes of maternal death worldwide. It can become fatal within minutes. A midwife is often the first and only person in the room when it happens.

The E-MOTIVE approach equips them to act with confidence. A simple calibrated drape replaces unreliable visual estimation with accurate blood loss measurement post-delivery. A midwife can then deliver an immediate bundle of life-saving treatments. Clinical trials found this reduced severe postpartum hemorrhage by 60 percent and improved detection from 51 to 93 percent.
Working with Ministry of Health- Uganda, CHAI has helped train over 500 providers across 125 facilities. More midwives acting promptly. More mothers surviving.

Watch their story 👇🏿

04/30/2026

Sometimes the barrier to reaching unvaccinated children isn't distance or access. It's bad data.

In Indonesia, around 10% of vaccinations delivered by private facilities weren't captured in government records — creating hundreds of thousands of false "zero-dose" cases. Children flagged as unreached who had already been vaccinated.

CHAI worked to integrate private sector data into the national registry and combine it with geospatial mapping.

The result: more than 220,000 false records corrected, and coverage among truly unreached children increased by up to 6%.

You have to know who is truly missing before you can find them.

Read the full story: https://ow.ly/cn7f50YQJMs

04/28/2026

This morning at , join us for our workshop on Advancing Hepatitis Integration Priorities in Global Fund GC8 | 8:00–8:55am ICT

Co-organized with the World Hepatitis Alliance and co-chaired by World Health Organization (WHO) — built for advocates who want to turn GC8 policy into funded country programs across hepatitis, harm reduction, and triple elimination.

We'll have our GC8 Integration Toolkit on hand. If you're in Bangkok, come find us.

Toolkit: https://ow.ly/7Ypo50YQEEb

04/28/2026

Every year, 14.3 million children reach their first birthday without a single vaccine.

Not because we can’t find them. Because the systems meant to reach them aren’t built to do it consistently.

The global health community has gotten good at identifying these ‘zero-dose’ children. But the harder problem is connecting them to care. Too often, the response becomes a new program sitting alongside routine systems rather than changing them.

CHAI's Alexio Mangwiro writes for Global Health Hub Germany on why integration — folding zero-dose efforts into how immunization systems work every day — is the only sustainable path. And what that looks like across Cambodia, Ethiopia, and Indonesia.

Read the full article: https://ow.ly/jYEk50YQIvI

04/28/2026

Countries applying for The Global Fund HIV grants in 2026 have a clear opportunity: bring hepatitis, harm reduction, and triple elimination into their HIV responses—and make the most of available resources.

In GC7, 20 of 21 countries CHAI supported included hepatitis-related funding requests. GC8 is the opportunity to go further. Our new GC8 Integration Toolkit gives countries the practical resources to do exactly that.

We’ll be presenting it live this week at in Bangkok, at our Thursday workshop co-organized with the World Hepatitis Alliance and co-chaired by World Health Organization (WHO).

Download: https://ow.ly/zHwb50YQCb0

Evidence Action, PATH, Healthy Futures Global, Gates Foundation, Unitaid, Children's Investment Fund Foundation, UNICEF

04/27/2026

The World Hepatitis Summit starts Tuesday in Bangkok — and CHAI is here.

This afternoon we're kicking things off at the plenary on access to hepatitis treatment, presenting new research on HCV market progress and sustainability.

🔹 Tue, Apr 28
2:30–3:30pm ICT | HCV Treatment Market: Progress, Dynamics, and Sustainability Outlook

🔹 Wed, Apr 29
8-8:55am ICT | Panel: Enhancing Linkage to Care
4-5:30pm ICT | Panel: Tests, Testing, and Reaching the People Who Need Them Most

🔹 Thu, Apr 30 |
8-8:55am ICT | Workshop: Advancing Hepatitis Integration Priorities in GC8 [with World Hepatitis Alliance, World Health Organization (WHO)
9:15-10:30am ICT | Plenary: Domestic Hepatitis Financing in a Changing Landscape

🔹 Throughout the summit | Research posters on hepatitis B integration, point-of-care diagnostics, and triple elimination across India, Nigeria, Rwanda, and Uganda

We hope to see you there.

04/24/2026

Ahead of this Saturday, new modeling evidence shows what two decades of sustained malaria investment has achieved.

From 2005 to 2024, the President's Malaria Initiative's (PMI) support for core malaria interventions across sub-Saharan Africa prevented an estimated 379 million malaria cases and 1.1 million deaths.

Roughly one in three people who received frontline antimalarial treatment for the first time did so because of PMI funding.

Two completely independent research teams, Imperial College London and the Malaria Atlas Project, with support from CHAI and funding from Coefficient Giving, used different methodologies and arrived at a similar magnitude of impact. That agreement substantially increases confidence that the findings reflect what happened on the ground.

Read the full analysis: https://ow.ly/kwzO50YOYSR

04/22/2026

We worked with governments in 14 countries in Africa and Asia to document key financing challenges: the problem isn't always how much money exists. It's whether the systems exist to move it.

The gaps seem technical. But the consequences are human: a health worker unpaid for six months, medicines expiring in warehouses, grants sitting unspent while services go undelivered.

And the root cause? Often, it’s that systems don’t talk to each other.

Logistics and finance using different facility codes. Payment systems that can't verify proof of work. Donor reporting tools disconnected from government financial systems.

The solution isn't another standalone system. It's shared standards and infrastructure built once that everything else can run on.

More on why this is a standards problem as much as a systems problem: https://ow.ly/afgG50YHciu


Gates Foundation, World Health Organization (WHO), UNICEF, eGovernments Foundation

Digital public infrastructure could transform public financial management in health across LMICs. CHAI’s new report shows how shared digital systems can get money where it needs to go.