Center for Stem Cell Therapeutics and Imaging

03/04/2021

CSTI’s new study showing the value of engineered off the shelf cellular therapy for metastatic cancer:

Basal-like breast cancer (BLBC) shows brain metastatic (BM) capability and overexpresses EGFR and death-receptors 4/5 (DR4/5); however, the anatomical location of BM prohibits efficient drug-delivery to these targetable markers. In this study, we developed BLBC-BM mouse models featuring different pa...

08/07/2020

Our new study published in Nature Comm. on immune phenotyping highly malignant brain tumors!

Syngeneic mouse models for glioblastoma (GBM) cannot fully recapitulate clinical findings and response to therapy in patients. Here the authors perform a comprehensive immune profiling of different syngeneic GBM tumour models and compare it with the immune landscape of GBM patients to identify simil...

07/23/2020

New Paper from Science Advances co-corresponded by Drs. Karp & Shah!

03/16/2020

Anxiety about the new coronavirus is understandable. But there are actions you can take –– or avoid –– to help you cope with anxious feelings and choices you can make to help yourself and others.

02/18/2020

Dr. Shah's Presentation at Austin Prep School! He had one of the largest audience!

https://www.austinprep.org/about-us/school-news/cougar-courier-archives/january-2020

02/03/2020

In a mouse model of glioblastoma, treatment with VEGF-C increases lymphatic drainage in the central nervous system and improves the immune response, suggesting that modulating meningeal lymphatics could enhance checkpoint inhibitor therapy.

12/20/2019

Holiday Gathering at Dr. Shah's place!

11/21/2019

Dr. Shah will be the speaker for tomorrow's Nanomedicine Lecture at Northeastern University at 3:25pm.

Cell based therapies are emerging as a promising strategy for cancer. We have developed cell surface receptor targeted adult stem cells, cancer cells and T cells expressing novel bi-functional immunomodulatory proteins and oncolytic viruses. Using recently established tumor models that mimic clinica...

06/24/2019

We are honored to receive Department of Defense (DoD) Impact Award and DoD Idea Award.

Learn about the awards, honors and grants that Brigham and Women's Hospital the organization and members of the BWH community have received.

03/22/2019

A happy news on Happy Friday! We've made it to Round 4 of STAT Madness 2019! THANK YOU SO MUCH for your votes through Round 1 to 3. It means a lot to us! Our team is going head-to-head with a team from the University of Utah this time. Before you step out for the fun activities, please vote for us!

If you are voting from your phone, please visit https://bit.ly/2GM10BE, click "Visit the bracket" and vote for us! Your votes are much appreciated! 😉

STAT Madness is a bracket-style contest to find the best innovation in science and medicine. Pick your favorites and help us crown a champ!

03/21/2019

Good morning! ☀️The voting for Round 3 of STAT Madness 2019 is closing tonight, so please make sure to vote for us! We are the one competing with UMass!

If you are voting from your phone, please visit https://bit.ly/2GM10BE, click "Visit the bracket" and vote for us! Your votes are much appreciated! 😉

STAT Madness is a bracket-style contest to find the best innovation in science and medicine. Pick your favorites and help us crown a champ!

03/18/2019

Another great news! Now, we’re on the Round 3 of STAT Madness 2019! THANK YOU for all the votes from Rounds 1 & 2! Now, we are the one competing with UMass, so please don't forget to vote for us again in

STAT Madness is a bracket-style contest to find the best innovation in science and medicine. Pick your favorites and help us crown a champ!