Dana-Farber Cancer Institute

Dana-Farber Cancer Institute Dana-Farber Cancer Institute is committed to providing expert, compassionate care.
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Dana-Farber Cancer Institute is committed to providing expert, compassionate care to children and adults with cancer, while advancing the understanding, treatment, cure, and prevention of cancer and related diseases.

Wondering if genetic testing is right for you? Join cancer genetic counselor Helen Dellas, MS, LGC, to learn about hered...
12/04/2025

Wondering if genetic testing is right for you? Join cancer genetic counselor Helen Dellas, MS, LGC, to learn about hereditary breast cancer, who may benefit from genetic testing, and how genetic testing results may help guide medical care for you and your family members.

Thursday, December 18 | Noon - 1 p.m. ET via Zoom

For more information and to register, visit https://bit.ly/4pjVI5H.

12/04/2025
A message from La’Shee, Capri’s mom, on GivingTuesday:“Thank you from the bottom of my heart. Your contribution doesn’t ...
12/02/2025

A message from La’Shee, Capri’s mom, on GivingTuesday:

“Thank you from the bottom of my heart. Your contribution doesn’t just fund research and treatments, it gives children like Capri the chance to keep living, laughing, and growing…You gave my daughter her future back, and you gave our family more precious time together.”

Your support today helps fuel the next victory over cancer for more patients like Capri. Donate now and your gift will be TRIPLED to stretch 3X as far: https://bit.ly/4pyph3C

Plus, you will receive a limited-edition Dana-Farber hat as a special thank-you.

Your words inspire our work 💙
12/02/2025

Your words inspire our work 💙

“Patients diagnosed with pancreatic cancer are living longer and living better. We are advancing into a greatly needed n...
11/29/2025

“Patients diagnosed with pancreatic cancer are living longer and living better. We are advancing into a greatly needed new era in pancreatic cancer treatment.” — Brian Wolpin, MD, MPH, director of the Hale Family Center for Pancreatic Cancer Research

Nearly 95% of pancreatic cancers carry RAS gene mutations that drive tumor growth—and new drugs that target RAS are showing promise in clinical trials. These RAS inhibitors are paving the way for new treatments that could improve long-term outcomes for patients all around the world.

Advancements in pancreatic cancer care and research have been fueled by the generosity of Dana-Farber Trustee Judith B. Hale and members of her family, Rob and Karen Hale, and Beth and Rich Kendall. Their philanthropy supports our researchers in their efforts to advance early detection and develop new treatments for patients in Boston and around the world. Thanks to the work in the Hale Family Center for Pancreatic Cancer Research, we are learning more about and advancing new treatments for pancreatic cancer every day.

Nolan Young has aspirations of a career in both the Air Force and FBI. After enduring chemotherapy, radiation, emergency...
11/26/2025

Nolan Young has aspirations of a career in both the Air Force and FBI. After enduring chemotherapy, radiation, emergency surgeries, and a stem cell transplant for T-cell acute lymphoblastic leukemia (T-ALL) — all before high school — basic training doesn’t seem quite so daunting.

While facing his health challenges, Nolan displayed toughness and determination and learned the importance of teamwork, partnering with his surgical, transplant, and oncology clinicians at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center.

“When I was in treatment, I developed a lot of appreciation for the doctors and nurses who saved me,” says Nolan. “They were always so helpful and nice to me, it made me want to help others.”

Throughout diagnosis, treatment, relapse, and transplant, Nolan’s multidisciplinary care team in the Hematologic Malignancy Center provided comprehensive, seamless care, ensuring his family never lost confidence or hope.

“It was such a huge team involved in the whole process, but we felt very connected to each one of them,” explains Nolan’s aunt, Lisa Chambers. “They were all terrific, and so was Nolan. He just showed so much resiliency.”

An early clue that something was wrong came on Thanksgiving in 2020. In the days that followed, he became increasingly tired and lethargic. When additional symptoms — bone and joint pain, fevers, and small red spots on his legs — appeared, his aunt took him for bloodwork.

“We were still in the car, driving home, when they called us and told us to go to Boston Children’s Hospital immediately,” recalls Chambers. “They knew that these were symptoms of ALL, and that same night at Children’s it was confirmed.”

Treatment began immediately. Pediatric hematologist/oncologist Angela M. Feraco, MD, MMSc, explained that Nolan needed to stay in the hospital for four weeks for initial chemotherapy.

“Dr. Feraco was wonderful,” says Chambers. “When you’re just getting situated into Dana-Farber/Boston Children’s, and dealing with the diagnosis and everything that happens next, it can be overwhelming. She was very comforting, including when Nolan ended up needing emergency surgery after that first month of treatment.”

“Nolan was released after 70 days on Feb. 22, 2021, his 11th birthday, but even after he got to go home he didn’t stay there too long,” Chambers recalls. “He had a bad reaction to one of the chemotherapy drugs, and started having stroke-like symptoms. We had to call EMS, and at one point he needed a feeding tube. He took it all like a champ.”

In April 2021, Nolan’s cancer returned.

“Because of the gut perforation Nolan suffered during that first month, we had to pause his leukemia-directed treatment to allow him to heal,” says Feraco. “We think his relapse was due to this pause, rather than inherent treatment resistance. We were therefore very hopeful that we could still achieve a second, long-lasting remission.”

Renewed chemotherapy and total-body irradiation put Nolan back into remission.

By August 2021, he was ready for a pediatric stem cell transplant led by specialists Christine Duncan, MD, and Helen Reed, MD, MPH.

“He was incredibly inquisitive, thoughtful, and mature for his age, and he always had a story, or three, that made me laugh,” recalls Reed. “If Nolan was scheduled to see me in clinic, I knew I was going to have some hearty laughs. I have no doubt that his attitude — his equanimity, curiosity, and humor — helped him through a difficult time.”

“At first I wasn’t sure how to feel, and kept changing how I acted,” Nolan says. “Then it just clicked in my head that I should be as positive as I can. It makes you feel better throughout the whole process.”

Another central part of Nolan’s recovery was the support of his Aunt Lisa. Reed agrees: “She was his rock through it all, always positive but grounded.”

Because of his weakened immune system, Nolan completed middle school virtually. When he returned as a high school freshman, he joined Junior ROTC to make new friends and rebuild his strength. He also became involved in community service.

“I don’t really mention what I’ve been through at school, unless I have to for medical reasons,” Nolan says. “I don’t want people to feel sympathetic.”

These days, Nolan is looking ahead. He plans to join the Air Force after high school, study criminal justice while serving, and eventually join the police or FBI.

To ensure he stays healthy, Nolan is seen annually in the David P. Perini Jr. Quality of Life Clinic for survivors of pediatric cancers and the Stem Cell Transplant Long-Term Follow-Up Program at Dana-Farber/Boston Children’s.

“Nolan’s prognosis at this point is excellent,” says Reed. “As far as I’m concerned, Nolan can do anything he wants to do!”

When Lenny Zakim was in treatment for multiple myeloma in the 1990s, one of his primary means of augmenting his chemothe...
11/24/2025

When Lenny Zakim was in treatment for multiple myeloma in the 1990s, one of his primary means of augmenting his chemotherapy and radiation came from home visits by his Tai Chi and Qigong instructor. Zakim dreamed of – and lobbied for – a central locale where he and other patients could manage their symptoms and improve their quality of life through this and other complementary therapies, such as acupuncture and massage, under the watchful eye of their oncologists.

In 2000, thanks largely to his persistence, the Leonard P. Zakim Center for Integrative Therapies and Healthy Living was established. At the time, the center occupied one small room near the lobby of the Dana building. During a recent 25th-anniversary event, Zakim Center faculty, staff, patients, and supporters celebrated its growth into a hub of clinical services, group programs, and transformative research – just steps from the large, state-of-the-art facility on Dana 1 that it now calls home.

“Lenny Zakim came to the leadership of Dana-Farber saying, 'We want a center that‘s not focused on finding new chemotherapy agents, but on helping people feel better by incorporating treatments that have been available for millennia to support patients as they go through therapy,’” Jennifer Ligibel, MD, director of the Zakim Center, told attendees at the celebratory event. “It was a radical concept, but very much in line with Dana-Farber’s long-term mission of not just treating cancer, but treating the patient and family as well. Over time, as the number of patients we treated grew, our footprint did as well, transforming into a beautiful center designed to be an oasis for patients going through the tumult of a cancer journey.”

Just as the Zakim Center’s physical size and patient population have expanded through the decades, so have its offerings. In addition to evidence-based practices such as acupuncture, massage, Tai Chi, meditation, and Qigong, the center now features exercise classes, strength training, one-on-one health coaching, dance and movement, and art and music therapy. Through the MyZakim online portal, patients and families can also access many of these programs virtually. Since 2020, the platform has had more than one million worldwide visits.

We were among the first cancer centers to combine integrative therapies with traditional Western oncology treatment, and have been a leader in conducting peer-reviewed, evidence-based research to prove their value when used in conjunction with traditional cancer treatment. The Zakim Center is a leader in research focused on both integrative therapies and healthy living, leading trials looking at the benefits of acupuncture, yoga, nutrition, exercise, and weight management in mitigating side effects of cancer treatment and improving outcomes – from quality of life to cancer recurrence and survival.

Today, most U.S. cancer centers provide some form of integrative therapy to their patients, supported by research conducted here. Ongoing projects led by Zakim Center co-directors Ligibel and Ting Bao, MD, MS, and its lead acupuncturist Weidong Lu, MB, PhD, hold the promise of establishing integrative therapies as a standard part of the care delivered to cancer patients everywhere.

Bao’s appointment as co-director in 2023 is a measure of this growth. Bao leads the Zakim Center’s integrative medicine consults program, building a clinic including an advanced practice coordinator and a clinical pharmacist to help patients navigate the most effective integrative therapies to incorporate into their cancer care, as well as to evaluate the safety of vitamins and supplements they may wish to take during treatment.

“Zakim Center research has proven what patients have told us, that integrative therapies actually helped reduce their nausea, pain, anxiety, fatigue, and other symptoms, and improve their quality of life,” stated Craig Bunnell, MD, MPH, chief medical officer, at the celebration. “That evidence has helped integrative medicine to enter the mainstream of oncology care – a place that it did not occupy 25 years ago. Cancer care is about more than chemotherapy, immunotherapy, surgery, and radiation, it’s about caring for the whole person – mind, body, and spirit. The Zakim Center has transformed the way we do that at Dana-Farber.”

Bunnell said Dana-Farber has fulfilled the vision of the late Lenny Zakim, who died in 1999 shortly after we announced the creation of the center that would bear his name. Zakim’s widow, Joyce, along with their children Josh, Deena, and Shari, were among attendees who spent the evening enjoying complimentary chair massages and ear acupuncture sessions, a dinner featuring healthy and creative dishes (and recipes) offered in Zakim Center nutritional consults, a poster presentation of research updates from Bao, and tours of the center’s clinical space.

Many past and current Zakim Center practitioners and leaders, including its first medical director David Rosenthal, MD, and former executive director Cynthia Medeiros, MSW, also attended the festivities. So was Lenny Zakim’s former Tai Chi instructor, Ramel “Rami” Rones, who has led Tai Chi, Qigong, and meditation in the Zakim Center for the last 25 years.

“The reach of the center is something I could never have envisioned because today, the center serves patients from all over the world in many different ways,” Joyce Zakim told the crowd. “Our veteran practitioners created the compassionate atmosphere that is being reinforced by newer professionals. The Zakim Center has an amazing team, and it’s inspiring to see their ability to convey the feeling of community to all patients who come to them knowing they will receive quality and compassionate care. It is a truly healing partnership, and Lenny would have loved to have seen how it’s developed.”

Being a teacher is what Marsha Olsen does best. But after a Whipple procedure — the removal of part of her pancreas, gal...
11/23/2025

Being a teacher is what Marsha Olsen does best. But after a Whipple procedure — the removal of part of her pancreas, gallbladder, and small intestine — she became a student again.

Marsha Olsen’s grandmother always used to say, “You have one body, take good care of it.” And for most of her life, Olsen has spread that message as a middle school physical education and health teacher instilling healthy habits in her students.

“I wanted all my students to have a positive experience in physical education, no matter their abilities,” she recalls. “It was important that they continue physical education outside of my class.”

Eventually she became a principal, but up until she retired, she remained a constant fixture at her school in Connecticut, making sure to be at every after-school athletic event, school play, and concert.

For years, Olsen had struggled with bouts of pancreatitis, a painful swelling of the pancreas, which resulted in more than a dozen hospitalizations. Every time, she was told it was due to her diet or lifestyle. She tried cutting out almost all fat, stopped drinking alcohol altogether, and made sure to stay hydrated, but the swelling kept coming back. Finally, a pancreatic specialist found the cause: a cyst in the pancreas duct.

This so-called intraductal papillary mucinous neoplasm is usually benign but can sometimes lead to pancreatic cancer. Physicians at the Dana-Farber Brigham Cancer Center Pancreas and Biliary Tumor Center determined Olsen should undergo a Whipple procedure. Removing parts of the pancreas, gallbladder, and small intestine would ensure that Olsen no longer experienced pancreatitis. A biopsy at the time also revealed a small cluster of cancer cells in the cyst. Fortunately, it was removed during the surgery, but Olsen was referred to a Dana-Farber oncologist for surveillance.

Since these organs play key roles in the digestive system, the Whipple procedure has major effects on the digestive system, including increased difficulty absorbing nutrients. Olsen’s Dana-Farber oncologist referred her to oncology dietitian Elizabeth Prentice, MS, RD, for support.

“Liz had answers for every one of my questions,” Olsen says. “She is an outstanding nutritional expert.”

When Olsen worried about some lower abdominal pain she experienced, Prentice encouraged her to introduce more probiotics in the diet to counteract a build-up of harmful bacteria. Prentice also helped Olsen find an appropriate pancreatic enzyme supplement and shared the latest research on healthy fats to dispel lingering concerns.

“We don’t eat in a vacuum,” Prentice says. “Our eating habits are influenced by many factors and experiences.”

Olsen is now back to her normal weight and feeling her healthiest self. Most days she can be found just after sunrise on a Cape Cod beach going for her daily walk before returning home to her work: developing and offering courses for teachers pursuing professional development at a state university in Massachusetts.

“My goal has always been to be active and productive and live to 100,” Olsen says. “Working with Liz and my care team, I still have the opportunity to reach my goal.”

Read Marsha’s full story: https://bit.ly/44kvRSV

For Lung Cancer Awareness Month, Narjust Florez, MD, joined boston25 to discuss what’s improving survival - research and...
11/22/2025

For Lung Cancer Awareness Month, Narjust Florez, MD, joined boston25 to discuss what’s improving survival - research and screening - and the concerning rise in diagnoses among non-smokers and young women.

Watch here:

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Join Mackenzie Cordova, LCSW, from the breast oncology social work team for a helpful session on navigating unexpected f...
11/21/2025

Join Mackenzie Cordova, LCSW, from the breast oncology social work team for a helpful session on navigating unexpected feelings that can come up during treatment of metastatic breast cancer, part of the 2025-2026 EMBRACE Metastatic Breast Cancer Forum, a series of free virtual educational programs for patients, families and loved ones.

December 5 | Noon – 1 p.m. ET

Learn how to mediate anxiety about the future, manage disappointment when treatment stops working, and gain insight on coping skills to help you adapt through life’s changes and challenges. A Q&A will follow the presentation. For more information and to register, please visit https://bit.ly/4ot0vll.

Our Midday Melodies series continues! 🎵 This week’s concert featured Pianist Robert Masi playing in the lobby of the Yaw...
11/21/2025

Our Midday Melodies series continues! 🎵
 
This week’s concert featured Pianist Robert Masi playing in the lobby of the Yawkey building. Join us next time on Tuesday, December 2 in the conference center on the third floor – either drop-in or stay for the full hour program.

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