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Personalized & precision medicine, hormone therapy & cognitive health care in Boulder, CO

Schedule your complimentary consultation with Dr. Knape: https://healthspancare.md-hq.com/schedule_unregistered

04/23/2026

𝗖𝗼𝗻𝗻𝗲𝗰𝘁𝗶𝗼𝗻 𝗶𝘀 𝗠𝗲𝗱𝗶𝗰𝗶𝗻𝗲 💊💗

Did you know that isolation often contributes to rapid cognitive decline? This week, we're talking about how connection helps repair brain function.

During COVID, we found that even small disruptions in connection had real impacts on mood, memory, and overall brain health. This was true for people of all ages, from children and teenagers to adults and the elderly.

The truth is: the brain is wired for connection, and without it, we see changes faster than most people expect.

To learn more about the brain as a social organ, check out our blog!
Link is in the comments below.

04/20/2026

𝗠𝗶𝗻𝗶𝗺𝗶𝘇𝗶𝗻𝗴 𝗖𝗼𝗴𝗻𝗶𝘁𝗶𝘃𝗲 𝗗𝗲𝗰𝗹𝗶𝗻𝗲
at Functional Forum Colorado
with and

I’m really looking forward to being part of this conversation on Minimizing Cognitive Decline at the Functional Forum Colorado on April 22, 2026!

This event, hosted by James Maskell and the Functional Forum, brings together practitioners who are asking better questions about brain health and how we can actually change the trajectory of cognitive decline.

For a long time, we were told that decline was just part of aging.
What we are seeing now tells a different story.

When you start to look at the drivers—things like inflammation, toxic burden, infections, and metabolic health—you begin to realize how much influence we actually have.

This won’t be a traditional lecture. It’s a space for thoughtful discussion around what’s working, what’s missing, and how we create more connected, effective models of care that support real outcomes for patients.

I’m grateful to be in conversation with colleagues who are committed to doing this work differently.

Hope to see you there!

04/20/2026

𝗧𝗵𝗲 𝗘𝗶𝗴𝗵𝘁 𝗣𝗶𝗹𝗹𝗮𝗿𝘀 𝗼𝗳 𝗕𝗿𝗮𝗶𝗻 𝗛𝗲𝗮𝗹𝘁𝗵: 𝗖𝗼𝗻𝗻𝗲𝗰𝘁𝗶𝗼𝗻 →

When it comes to improving brain and body health, “connection” is often talked about in a way that feels vague or overly simplistic.

Call a friend.
Spend more time with people.
Be more social.

But in reality, meaningful connection isn’t about the 𝘢𝘮𝘰𝘶𝘯𝘵 of interaction.

The key is 𝘲𝘶𝘢𝘭𝘪𝘵𝘺.

Instead of filling your schedule with more social time because it’s “what you’re supposed to do,” it’s important to focus on the relationships and environments that actually support your nervous system.

In the next pillar of BrainSpan Bootcamp, we explore how connection directly impacts brain health, from regulating stress responses to shaping emotional resilience and cognitive function.

This is a highly individualized process, because not all connection is supportive.

Some relationships create safety, trust, and regulation.
Others contribute to stress, dysregulation, and inflammation.

That’s why 𝘥𝘪𝘴𝘤𝘦𝘳𝘯𝘮𝘦𝘯𝘵 matters.

When you understand which relationships genuinely support your well-being, you can invest your time and energy in ways that strengthen your brain without unnecessary overwhelm.

If you’re interested in a more personalized, evidence-informed approach to brain health:

Comment 𝗕𝗥𝗔𝗜𝗡𝗦𝗣𝗔𝗡 to learn more about the next live cohort of BrainSpan Bootcamp or book a meet and greet to explore the targeted assessments available at our clinic.

04/17/2026

𝗧𝗵𝗶𝗻𝗴𝘀 𝘁𝗼 𝗥𝗲𝗺𝗼𝘃𝗲 𝘁𝗼 𝗢𝗽𝘁𝗶𝗺𝗶𝘇𝗲 𝗕𝗿𝗮𝗶𝗻 𝗛𝗲𝗮𝗹𝘁𝗵 ➡️

This week, we've been talking about how removing toxins from our environment can help optimize brain health.→

The key to doing this effectively is by 𝘀𝘁𝗮𝗿𝘁𝗶𝗻𝗴 𝘀𝗺𝗮𝗹𝗹 and 𝘀𝘁𝗮𝘆𝗶𝗻𝗴 𝗰𝗼𝗻𝘀𝗶𝘀𝘁𝗲𝗻𝘁. 🧠

Pick ONE thing from this checklist and do it this week.

Also, save this and come back to it.

Small incremental changes are how real brain change happens.

Which removal strategy are you choosing first?
Let us know in the comments below ⬇️

04/17/2026

𝟱 𝗧𝗼𝘅𝗶𝗻𝘀 𝗧𝗵𝗮𝘁 𝗔𝗿𝗲 𝗤𝘂𝗶𝗲𝘁𝗹𝘆 𝗛𝘂𝗿𝘁𝗶𝗻𝗴 𝗬𝗼𝘂𝗿 𝗕𝗿𝗮𝗶𝗻 (𝗣𝗮𝗿𝘁 𝗜𝗜) →

If you caught Part I of my reel on common toxins that are interfering with brain health, you already know that some of the biggest hits to your brain are not always the most obvious.

So what do you actually do with that information?

You do not need to overhaul your entire life. In fact, that is usually what leads to overwhelm and burnout. Instead, focus on one simple shift at a time.

→ Maybe it is filtering your water to remove some of the natural impurities coming out of your tap.

→ Maybe it is adding an air purifier to your bedroom to deal with indoor pollution.

→ Maybe it is reevaluating certain relationships to ensure they are life-giving and healthy.

These are small decisions, but they add up. Your brain is constantly responding to the environment you create for it.

The goal is not perfection. It is awareness, followed by intentional action.

Start where you are. Keep it simple. Build momentum.

Your future brain will thank you. 🧠

04/15/2026

𝟱 𝗧𝗼𝘅𝗶𝗻𝘀 𝗧𝗵𝗮𝘁 𝗔𝗿𝗲 𝗤𝘂𝗶𝗲𝘁𝗹𝘆 𝗛𝘂𝗿𝘁𝗶𝗻𝗴 𝗬𝗼𝘂𝗿 𝗕𝗿𝗮𝗶𝗻 →

If you are doing all the “right” things for your health but still feeling foggy, tired, or not quite like yourself… this might be worth a closer look.

There are a handful of everyday exposures that can quietly interfere with how your brain functions. Not in a dramatic, overnight way. But slowly, over time, in ways that are easy to overlook.

I am talking about things like heavy metals, mold, plastics, pesticides, and synthetic fragrance.

These are not meant to scare you. They are meant to empower you.

Because once you start noticing what is in your environment, you can begin making small, thoughtful shifts. And those small shifts can make a meaningful difference in how clearly you think, how steady your energy feels, and how well your brain is supported long term.

You do not have to change everything at once. Start with one area. Stay curious. Build from there.

Your brain is worth protecting. 🧠✨

04/13/2026

𝗧𝗵𝗲 𝗘𝗶𝗴𝗵𝘁 𝗣𝗶𝗹𝗹𝗮𝗿𝘀 𝗼𝗳 𝗕𝗿𝗮𝗶𝗻 𝗛𝗲𝗮𝗹𝘁𝗵: 𝗥𝗲𝗺𝗼𝘃𝗲 𝗧𝗼𝘅𝗶𝗻𝘀 →

When it comes to improving brain and body health, “removing toxins” often gets a bad reputation because it can sound restrictive or overwhelming.

Strict diets.
Only natural cleaning products.
Avoiding certain environments out of fear of inflammation or illness.

But in reality, creating a cleaner, clearer environment that your body actually feels good in doesn’t need to be that extreme.

The key is 𝘱𝘳𝘦𝘤𝘪𝘴𝘪𝘰𝘯.

Instead of removing things in bulk because it’s “what you’re supposed to do,” it's important to focus on what is actually impacting 𝘺𝘰𝘶.

In the next pillar of BrainSpan Bootcamp, we explore how to identify and remove specific toxins and stressors that contribute to inflammation and chronic conditions.

This is a highly personalized process, because from a clinical perspective, there is no universal list that applies to everyone.

Each person’s physiology responds differently to foods, environments, and stress. What creates inflammation for one person may be completely neutral for another.

That’s why 𝘵𝘢𝘳𝘨𝘦𝘵𝘦𝘥 𝘢𝘴𝘴𝘦𝘴𝘴𝘮𝘦𝘯𝘵 matters.

When you understand your unique triggers, you can make focused, strategic changes that support your brain without unnecessary restriction.

If you’re interested in a more personalized, evidence-informed approach to brain health:

Comment 𝗕𝗥𝗔𝗜𝗡𝗦𝗣𝗔𝗡 to learn more about the next live cohort of BrainSpan Bootcamp or book a meet and greet to explore the targeted assessments available at our clinic.

04/10/2026

𝗧𝗶𝗽𝘀 𝗳𝗼𝗿 𝗚𝗿𝗼𝘄𝗶𝗻𝗴 𝗬𝗼𝘂𝗿 𝗕𝗿𝗮𝗶𝗻'𝘀 𝗖𝗮𝗽𝗮𝗰𝗶𝘁𝘆 →

Most people try to “train” their brain the same way they train their body… by pushing harder.

But your brain doesn’t respond to force the way you think it does.

When you’re tense, rushing, or quietly judging yourself, your system shifts into a protective state.

In that state, the hippocampus struggles to encode new information, and the prefrontal cortex has a harder time staying flexible and creative.

You might still be “doing the work”…
but very little of it is actually sticking.

Because learning isn’t just about effort.
𝗜𝘁’𝘀 𝗮𝗯𝗼𝘂𝘁 𝘁𝗵𝗲 𝗰𝗼𝗻𝗱𝗶𝘁𝗶𝗼𝗻𝘀 𝘆𝗼𝘂 𝗰𝗿𝗲𝗮𝘁𝗲 𝗶𝗻𝘁𝗲𝗿𝗻𝗮𝗹𝗹𝘆.

𝗬𝗼𝘂𝗿 𝗯𝗿𝗮𝗶𝗻 𝗯𝘂𝗶𝗹𝗱𝘀 𝗻𝗲𝘄 𝗽𝗮𝘁𝗵𝘄𝗮𝘆𝘀 𝘄𝗵𝗲𝗻 𝘀𝗼𝗺𝗲𝘁𝗵𝗶𝗻𝗴 𝗳𝗲𝗲𝗹𝘀 𝗲𝗻𝗴𝗮𝗴𝗶𝗻𝗴 𝗲𝗻𝗼𝘂𝗴𝗵 𝘁𝗼 𝗵𝗼𝗹𝗱 𝘆𝗼𝘂𝗿 𝗮𝘁𝘁𝗲𝗻𝘁𝗶𝗼𝗻, 𝗯𝘂𝘁 𝘀𝗮𝗳𝗲 𝗲𝗻𝗼𝘂𝗴𝗵 𝘁𝗵𝗮𝘁 𝘆𝗼𝘂𝗿 𝘀𝘆𝘀𝘁𝗲𝗺 𝗱𝗼𝗲𝘀𝗻’𝘁 𝗻𝗲𝗲𝗱 𝘁𝗼 𝗯𝗿𝗮𝗰𝗲.

That space is subtle.
It often feels like 𝙞𝙣𝙩𝙚𝙧𝙚𝙨𝙩, 𝙡𝙞𝙜𝙝𝙩𝙣𝙚𝙨𝙨, 𝙚𝙫𝙚𝙣 𝙖 𝙗𝙞𝙩 𝙤𝙛 𝙥𝙡𝙖𝙮.

So instead of asking yourself how to optimize your brain,
𝘁𝗿𝘆 𝗻𝗼𝘁𝗶𝗰𝗶𝗻𝗴 𝘄𝗵𝗮𝘁 𝗻𝗮𝘁𝘂𝗿𝗮𝗹𝗹𝘆 𝗽𝘂𝗹𝗹𝘀 𝘆𝗼𝘂 𝗶𝗻.

→ What sparks your attention without force?
→ What feels just a little unfamiliar, but not overwhelming?

𝙁𝙤𝙡𝙡𝙤𝙬 𝙩𝙝𝙖𝙩.

Give it a few minutes of your full attention, without trying to be “good” at it.

You’re not just passing time.
You’re creating the conditions your brain needs to change. 🧠

To learn more about 𝗕𝗿𝗮𝗶𝗻𝗦𝗽𝗮𝗻 𝗕𝗼𝗼𝘁𝗰𝗮𝗺𝗽, a 12-week program where we explore more about how to grow our brain's capacity to improve our quality of life and support our everyday living, comment BRAINSPAN below!

*𝗕𝗿𝗮𝗶𝗻𝗦𝗽𝗮𝗻 𝗕𝗼𝗼𝘁𝗰𝗮𝗺𝗽 is an original program created by and .

04/09/2026

𝗔𝗴𝗶𝗻𝗴 𝗮𝘁 𝗔𝗹𝘁𝗶𝘁𝘂𝗱𝗲 𝟮𝟬𝟮𝟲!

This past Saturday, I had the privilege of speaking at Aging with Altitude 2026.

I shared a talk on hormone health, something that shapes how we feel day to day from energy and mood to strength and long-term brain health. It was incredibly meaningful to be surrounded by other practitioners and experts who care deeply about helping people age with intention, clarity, and vitality.

One of the highlights for me was meeting clients in person. Being able to connect face to face, have real conversations, and hear more of your stories meant so much. I also shared a hormone health handout that brings together key takeaways from my talk in a practical and easy-to-understand way. If you would like a copy, comment 𝗛𝗢𝗥𝗠𝗢𝗡𝗘𝗦 and I will send it to you.

We also had some fun testing grip strength with a few kind volunteers. Grip strength is a simple but powerful marker of overall health. It reflects muscle mass, which is influenced by hormones like estrogen and testosterone. As these hormones shift with age, strength often changes too, making grip strength a useful and accessible way to track resilience over time.

Feeling grateful for the conversations, the connections, and the opportunity to be part of this community!

04/07/2026

𝗧𝗵𝗲 𝗘𝗶𝗴𝗵𝘁 𝗣𝗶𝗹𝗹𝗮𝗿𝘀 𝗼𝗳 𝗕𝗿𝗮𝗶𝗻 𝗛𝗲𝗮𝗹𝘁𝗵 — 𝗚𝗥𝗢𝗪! 🌱

𝘞𝘩𝘦𝘯’𝘴 𝘵𝘩𝘦 𝘭𝘢𝘴𝘵 𝘵𝘪𝘮𝘦 𝘺𝘰𝘶 𝘵𝘳𝘪𝘦𝘥 𝘴𝘰𝘮𝘦𝘵𝘩𝘪𝘯𝘨 𝘯𝘦𝘸?

Your brain thrives on 𝘯𝘰𝘷𝘦𝘭𝘵𝘺.

New experiences challenge old patterns and spark new neural connections, which is why learning new things can be beneficial for the brain.

Learning something unfamiliar, whether it’s a skill, a hobby, or even a different routine, keeps your brain flexible.

Not only that, it 𝘴𝘵𝘳𝘦𝘯𝘨𝘵𝘩𝘦𝘯𝘴 𝘮𝘦𝘮𝘰𝘳𝘺 and 𝘣𝘶𝘪𝘭𝘥𝘴 𝘳𝘦𝘴𝘪𝘭𝘪𝘦𝘯𝘤𝘦.

And it doesn’t have to be big.

Try a new route on your way to work.
Test out a new recipe over the weekend.
Consider a new way of thinking when things start to feel stuck.

Small moments of novelty, repeated over time, are what shape a more adaptable, energized brain.

What’s one new thing you’ll try this week to make your brain happy?

04/03/2026

𝟴 𝗦𝗶𝗺𝗽𝗹𝗲 𝗧𝗶𝗽𝘀 𝗳𝗼𝗿 𝗞𝗲𝗲𝗽𝗶𝗻𝗴 𝗧𝗿𝗮𝗰𝗸 𝗼𝗳 𝗬𝗼𝘂𝗿 𝗛𝗲𝗮𝗹𝘁𝗵 →

So many people start tracking everything… and end up learning nothing.

This is your reminder to simplify:
→ Track one meaningful metric
→ Use tools only if they support you
→ Look for patterns, not perfect days

Because real change doesn’t come from doing more.
It comes from 𝘯𝘰𝘵𝘪𝘤𝘪𝘯𝘨 what actually drives progress and brings about sustainable change.

Which of these 10 tips resonated with you? ✨
Let us know in the comments below! ⬇️

04/02/2026

𝗔𝗴𝗶𝗻𝗴 𝗮𝘁 𝗔𝗹𝘁𝗶𝘁𝘂𝗱𝗲 𝟮𝟬𝟮𝟲 — 𝗛𝗼𝗿𝗺𝗼𝗻𝗲𝘀, 𝗧𝗵𝗲 𝗕𝗿𝗮𝗶𝗻 𝗮𝗻𝗱 𝗟𝗼𝗻𝗴𝗲𝘃𝗶𝘁𝘆!

I’m excited to share that I’ll be speaking at the upcoming 𝗔𝗴𝗶𝗻𝗴 𝗮𝘁 𝗔𝗹𝘁𝗶𝘁𝘂𝗱𝗲 𝗦𝗽𝗿𝗶𝗻𝗴 𝗘𝘅𝗽𝗼 on 𝗦𝗮𝘁𝘂𝗿𝗱𝗮𝘆, 𝗔𝗽𝗿𝗶𝗹 𝟰, 𝟮𝟬𝟮𝟲, 𝗳𝗿𝗼𝗺 𝟭𝟭:𝟯𝟬 to 𝟭𝟭:𝟱𝟬 𝗮.𝗺. 𝗶𝗻 L𝗲𝘃𝗶𝗻 𝗛𝗮𝗹𝗹 𝗮𝘁 𝘁𝗵𝗲 𝗕𝗼𝘂𝗹𝗱𝗲𝗿 𝗝𝗖𝗖.

This is one of those rare community events that truly brings together the full picture of aging well—from health, nutrition, and movement to financial planning, home support, and beyond. It’s a thoughtful, inspiring space designed to help you navigate this stage of life not just with information, but with clarity, confidence, and connection.

If you’ve ever found yourself wondering:

→ Why don’t I feel like myself anymore?
→ Is this just aging… or is something changeable?
→ What can I actually do to protect my brain and energy long-term?

—you are not alone.

In my talk, “𝗛𝗼𝗿𝗺𝗼𝗻𝗲𝘀, 𝘁𝗵𝗲 𝗔𝗴𝗶𝗻𝗴 𝗕𝗿𝗮𝗶𝗻, 𝗮𝗻𝗱 𝗟𝗼𝗻𝗴𝗲𝘃𝗶𝘁𝘆,” we’ll explore how hormones shape not just symptoms like sleep, mood, and energy—but the underlying biology of brain health itself. I’ll walk through a more modern, systems-based perspective on aging, including how hormone shifts interact with metabolism, stress, and cognitive function—and what that means for prevention and vitality.

𝗧𝗵𝗲 𝗲𝘃𝗲𝗻𝘁 𝗶𝘀 𝗳𝗿𝗲𝗲 𝗮𝗻𝗱 𝗼𝗽𝗲𝗻 𝘁𝗼 𝘁𝗵𝗲 𝗰𝗼𝗺𝗺𝘂𝗻𝗶𝘁𝘆.
No registration is required—just bring yourself, a friend, and a bit of curiosity!

If you’d like to learn more about my talk, you can find additional details at the link below.

I hope to see you there!

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2523 Broadway Suite 201
Boulder, CO
80304

Opening Hours

Monday	9am - 4pm
Tuesday	9am - 4pm
Wednesday	9am - 4pm
Thursday	9am - 4pm
Friday	9am - 4pm

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http://drjesshealth.com/

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