The Yeoman Lab

08/31/2021

Please join us this Thursday, Sept 2, either in person or on webex, for the first speaker in the 21-22 Bair Ranch Foundation Seminar Series. Dr. Nick Serao from Iowa State University joins us to discuss "Learning and Applying Statistics: What Could Go Wrong?" Webex link: https://montana.webex.com/montana/j.php?MTID=m657ad223a64870720c1c28f7b364f1ad

We are excited to bring you a fantastic lineup of speakers this year!

07/30/2021

Congrats to Herlin (Eri) Kadriu (MS candidate in Biotechnology) who was selected to give an oral seminar at the 2021 Conference of Research Workers in Animal Diseases (CRWAD) Dec 3-7th in Chicago, Illinois. Eri will present his research involving the development of bovine intestinal organoid models to study immune modulation by gut microbes.

07/28/2021

Congrats to Savannah Grace who successfully defended her Master’s thesis on Thursday. She is joining the lab of Samantha Wisely (the University of Florida) where she will study epizootic hemorrhagic disease in Cervidae as a doctoral student.

• Savannah joined the lab as an undergraduate in 2018, where she worked on various projects involving the vaginal metabolome and microbiome. Savannah gained experience cultivating fastidious bacterial species, learned a variety of statistical techniques, and how to use R.

• In 2019, she began a Master's program in the Department of Animal and Range Sciences where she examined methyllycaconitine-degradative activity in wild ruminant gut microbiomes. She learned how to culture anaerobic bacteria and fungi, and mass spectrometry.

• Savannah’s concern and care for the lab and her peers is evidenced by her willingness to step in and help with any project, in any capacity. As such, her time here will culminate in 2 first authorships (late-stage prep), 1 second authorship (late stage prep), and 1 third authorship. Two of these papers involve her thesis project, and two involve the vaginal microbiota.

The Yeoman lab members are so sad to see her go, but we know that Savannah will continue to thrive!

06/03/2021

Lab day out!

04/30/2021

Another great semester down and time for a little lab outing. Thanks to all for making this past year productive despite the challenges.

03/20/2021

Congrats to Grad Student Savannah Grace who won 1st place in the student poster competition at the MT wildlife society conference last month for her work describing the methyllycaconitine-degradative activity in wild ruminant gut microbiomes.

03/07/2021

More than just biomarkers was the hypothesis we put forth in 2015. Here we show biogenic amines that are produced by amino acid decarboxylation reactions are not only precursors to a loss of Lactobacillus spp. and Bacterial vaginosis but also directly affect Lactobacillus spp. growth and their production of lactic acid, undermining what is dogmatically their primary protective mechanism. Great work Joanna Borgogna and everyone - a lot of hard work and late nights went into this study!

Bacterial vaginosis (BV) is the most common vaginal disorder of reproductive-aged women, yet its etiology remains enigmatic. One clinical symptom of BV, malodor, is linked to the microbial production of biogenic amines (BA). Using targeted liquid chromatography mass-spectrometry, we analyzed 149 lon...

03/03/2021

Competition among major cellulose-degrading bacteria of the rumen has been well described through in vitro studies and affects the rate at which plant fiber is degraded. Using a gnotobiotic (microbially-restricted) lamb model, we examine this competition in situ using a comprehensive suite of molecular analyses, including metagenomic, metatranscriptomic, metabolomic, and xymogram assessments to show these competitive interactions also play out in vivo with complex results on enzyme activities, fibrolysis, and the metabolomic response

Fibrobacter succinogenes, Ruminococcus albus, and Ruminococcus flavefaciens are the three predominant cellulolytic bacterial species found in the rumen. In vitro studies have shown that these species compete for adherence to, and growth upon, cellulosic biomass. Yet their molecular interactions in v...

09/11/2020

Last year hunters from all over Montana helped us collect almost 100 wild rumen samples that are being used to isolate microbes capable of degrading toxins found in widely distributed range plants. This year we're looking for their help again to add to that collection with the goal of exploring and defining the seasonal, geographic, and species influences on the ruminal microbiota of these highly valued animals. If you are or know a hunter that might be able to help us out please let us know.

07/31/2020

Been saying this for years! Hopefully, this is the end of this distraction.

Study rebuts controversial hints of a fetal microbiome

07/24/2020

That’s our ep Motion pictured in action aiding COVID-19 testing here in MT!

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03/11/2020

In humans, the vaginal microbiome has been associated with two of three major forms of infertility (anovular and especially tubal defect) and can alter risks of pre-term birth (in humans this is birth before 37 weeks) and spontaneous abortion (miscarriage). Studies from our labs first graduate student, Jeffrey Swartz did NOT find a similar influence of the ovine vaginal microbiota on reproductive performance of sheep. However, as part of a collaboration involving our lab, graduate student Leticia Sanglard and Nick Serao at Iowa state (and others) have shown the vaginal microbiota of commercial pigs can be used to classify sows into having low or high farrowing performance.
https://www.nature.com/articles/s41598-020-59955-8