Iron Will Fitness Club

03/29/2024

So true.

10/23/2023

10/13/2023

07/20/2023

The included studies had a total of 46,728,889 participants. The findings suggest that the use of statins is associated with a decrease in insulin sensitivity and insulin resistance. This systematic review provides evidence that the use of statins may have an adverse effect on insulin sensitivity and increase insulin resistance. These findings may have important clinical implications for individuals on statin therapy, especially those at risk of developing diabetes.

There has been mixed and inconclusive evidence regarding the relationship between statin usage and insulin intolerance. This systematic review aims to comprehensively explore the link between the use of statins and insulin intolerance. We systematically searched MEDLINE, PubMed, PubMed Central (PMC)...

06/19/2023

Let's play follow the leader. What can go wrong?

06/06/2023

https://twitter.com/calleymeans/status/1666090180724523014?s=20

05/23/2023

There is so much to unlearn about your health.

Never stop learning.

We never stop teaching.

PURPOSE Adults with a triple multimorbidity (hypertension, prediabetes or type 2 diabetes, and overweight or obesity), are at increased risk of serious health complications, but experts disagree on which dietary patterns and support strategies should be recommended. METHODS We randomized 94 adults f...

05/21/2023

It astounds me that medical leaders fail to realize there has not been a successful pharmaceutical treatment for ANY chronic disease in American history.

💊More statins? More heart disease.
💊More metformin? More diabetes.
💊More SSRIs? More depression and su***de.
💊More Adderall? More ADHD.
💊More Ambien? More insomnia.
💊$300b per year on cancer treatment? Increasing rates of cancer.
💊More Alzheimer’s drugs? More Alzheimer’s.
💊More Humira? More arthritis.
💊More Vi**ra? More ED
💊More spending on fertility? More infertility.

The history of pharmaceutical treatments for chronic disease has been a nearly unmitigated, unanimous failure - unless the goal of these drugs should be something other than curing and reversing the conditions they are ostensibly made to treat.

As Peter Attia, MD has pointed out - if you control for acute/infectious diseases, life expectancy has been largely flat in last 100 years.

Chronic disease pharmaceuticals have been a universal failure because they are based on a lie that conditions like heart disease, diabetes, PCOS, and obesity are different things.

They are actually the exact same thing (metabolic dysfunction) - and it is misleading patients to say they can address them in siloes with a pill.

Chronic disease pharma is a moral hazard. The implicit message a patient receives if they are on metformin/statins is they can continue their bad diet if they take their meds (this *literally* is the guidance the American Diabetes Association gave until 2018). But as we continue our sedentary, ultra-processed lifestyle, comorbidities continue to rise.

What’s so tragic is we could steer the $4 trillion of healthcare incentives to actually prevent and reverse these conditions. If you cut added sugar 80% from the American diet, you would wipe out a large percentage of heart disease and diabetes cases and save trillions from our budget.

With the uninterrupted record of failure for chronic disease pharma, it is astounding medical leaders go unquestioned when they herald a new miracle cure.

We’ve completely lost our way and we need to stop doing what we’ve been doing to get back on track. -- Calley Means

05/02/2023

Childhood Obesity is an epidemic.

A recent article published in JAMA Pediatrics discusses the American Academy of Pediatrics (AAP) clinical practice guideline for the evaluation and treatment of children with obesity. The AAP guideline emphasizes weight loss drugs and bariatric surgery despite limited research on novel dietary obesity treatment in any age group. Although the physiologic actions of anti-obesity drugs and surgery may have similarities to diet, few high-quality studies have been conducted to test novel dietary obesity treatments. However, low-glycemic load diets have shown promise in delaying hunger after eating, which may augment satiety induced by the direct actions of long-acting GLP-1 RA in the brain. A low-glycemic load diet also decreases leptin levels, suggestive of lower leptin resistance, and ghrelin levels and increasing adiponectin levels. Similarities between low-glycemic load diets and the GLP-1 RA include the slowing of gastric emptying, which reduces overall insulin demand. The efficacy of low-glycemic load diets in weight loss may approach the efficacy of the GLP-1 RAs in weight loss, but high-quality clinical trials will be needed to know the full potential of low-glycemic load diets. The article argues that the justified excitement surrounding new-generation weight loss drugs should not lead to deprioritizing development of nonpharmacologic interventions aimed at the root causes of the epidemic.

This Viewpoint considers the best approaches for treating obesity in youth and argues that better funding is needed for new dietary treatments and reimbursement for behavioral interventions.

05/02/2023

Looking for a workout routine that helps you build real-world strength and improve your daily life activities? Look no further than functional fitness! By focusing on exercises that mimic everyday movements, such as squatting, lifting, and twisting, functional fitness can help you improve your balance, stability, flexibility, and overall fitness level. Plus, it's a fun and challenging way to work out! Whether you're a fitness beginner or a seasoned athlete, incorporating functional fitness into your routine can bring a wealth of benefits. So why not give it a try? Your body (and daily activities) will thank you!

04/22/2023

Get it?