01/22/2026
Prostate cancer tumor burden may be higher than it looks on your reports.
A new GoPath study, presented in part at the 101st Annual Meeting of the Western Section of the AUA, shows that using slide core length instead of gross core length can shift percent tumor involvement from 54.79% to 75.52% in the same biopsy cores. The blog details how this discrepancy affects common thresholds such as the 50% involvement cut‑off in Gleason 3+3 and 3+4 disease, with direct impact on active surveillance decisions. The study outlines practical steps for clinicians and pathologists to standardize slide‑based measurements and improve confidence in risk stratification.
Read more: https://www.gopathdx.com/blog/tpost/yvjt72xy41-the-difference-of-percent-tumor-involvem