Genomate Health

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Genomate Health

Genomate Health is a digital health company that develops computational solutions for personalized medicine.

10/27/2025

This week, our Founder and Chief Scientific Officer, Istvan Petak MD, PhD, will speak at the IOSI Teaching Conferences in Bellinzona, Switzerland.

His talk on “Computer-Assisted Molecularly Targeted Therapy in Oncology” will explore how oncologists can make sense of complex molecular profiles using computational reasoning, turning data into clearer, more confident treatment decisions.

At Genomate Health, we believe precision medicine should be both clinically sound and practically usable. We’re glad to be part of conversations that bring those two goals closer together.

10/23/2025

Every breakthrough in targeted therapy reminds us how crucial molecular insight really is. For example, Itovebi (inavolisib) has been approved in the US and EU for HR+, HER2-, PIK3CA-mutated advanced breast cancer, based on results from the INAVO-120 trial.

By inhibiting the PI3Kα pathway, it offers new hope for patients whose cancers have developed resistance to endocrine therapy. The approval also reinforces a broader shift: genotyping isn’t just for diagnosis anymore, it’s for every treatment decision along the way.

At Genomate Health, we support oncologists in navigating these molecular complexities with clarity and precision reasoning.

10/20/2025

made one thing clear: oncology is shifting from empirical decision-making to a molecularly defined, data-driven discipline.

For oncologists, this means navigating an expanding universe of molecular data, AI-generated insights, and new treatment options, along with the growing challenge of determining what is clinically relevant and reproducible for each patient.
For pharma, AI is driving an unprecedented surge of new targets and compounds. The next challenge is accelerating clinical validation, not by adding complexity but by integrating biological reasoning earlier in development.

At Genomate Health, we understand both perspectives. Genomate, our computational reasoning platform, supports oncologists interpret complex molecular profiles with clarity and confidence in daily practice. It also enables drug developers to design smarter trials, prioritize targets with higher clinical probability, and identify mechanisms of response before entering the clinic.

The result is better decisions from bench to bedside, and precision therapies reaching patients faster with scientific and clinical confidence.

10/14/2025

You don’t need more data. You need clarity.

These days, the challenge isn’t access to NGS testing, it’s knowing what to do with it, especially when time is short and tumor board access is limited.

Genomate offers a practical, clinician-ready alternative:
✔️ Goes beyond 1:1 biomarker-drug matching
✔️ Uses computational reasoning to model the full tumor profile
✔️ Returns a ranked, evidence-based treatment options report in 2–3 business days

No disruption to your workflow. Just clearer options when standard paths don’t apply.

If you’re treating a case that doesn’t fit the standard path, we’re here to help you see what matters most: https://www.genomate.health/order

10/10/2025

This World Mental Health Day, we’re reminded that behind every case, there’s a patient, a family, and a care team.

Taking care of minds is as critical as treating disease.

At Genomate Health, we see the complexity of cancer care every day: the uncertainty, the decisions, the weight of getting it right. While we focus on providing clinical clarity, we know that clarity alone isn’t enough. Patients and providers alike need space to process, to pause, and to feel supported.

Today is a reminder that precision must go hand-in-hand with compassion. Mental health isn’t a separate part of care, it’s part of the whole.

10/09/2025

We’ll be at ESMO 2025 in Berlin from October 17–21, and we’re looking forward to connecting on-site.

We’re attending to listen, learn, and meet others working toward the same goal: making precision oncology more consistent, more accessible, and more actionable, wherever care is delivered.

If you're thinking about the challenges of decision support, biomarker-driven therapy, or scaling precision beyond academic centers, let’s find time to talk.

10/07/2025

Liver cancer care is rarely straightforward.
Behind every diagnosis is a unique molecular profile, a story written in data that’s often difficult to interpret.

Genomics helps us read those stories.
Computational reasoning helps us understand what they mean.

By transforming complex genomic data into clear, evidence-based insights, Genomate empowers clinicians to make confident treatment decisions and bring precision care to every patient who needs it.

Because better reasoning leads to better outcomes.

10/03/2025

We all know the theory: early detection saves lives.

But the reality is it’s easy to delay.
Easy to skip the appointment.
Easy to assume it can wait.

Sometimes, it can. But sometimes, it can’t.

This is a reminder to take action, even if it’s uncomfortable or inconvenient:
- Schedule the screening you’ve been meaning to book
- Have the health conversation you’ve been avoiding
- Pay attention to changes that don’t feel urgent, but feel different
- Follow up, even if you’re afraid of the answer

Awareness is where it begins. Precision is how it moves forward.
Because the best care is the one that’s built around you.

10/02/2025

Excited to share that we will be presenting our latest work at the AACR-KCA Joint Conference on Precision Medicine in Cancer!

Our study evaluates the Digital Drug Assignment (DDA) system, a knowledge-graph-based computational reasoning tool designed to support treatment decision-making in precision oncology.

Key highlights:
↘ We analyzed 178 solid tumors using high-throughput patient-derived xenograft (PDX) models, covering over 1,100 molecularly targeted agent (MTA) monotherapies.
↘ DDA-generated drug scores consistently identified MTAs that outperformed standard chemotherapy in terms of median progression-free survival.
↘ Importantly, overall MTA treatment showed no significant benefit over chemotherapy, underscoring the need for systematic and reproducible assignment approaches like DDA.

Our results provide strong evidence that knowledge-graph-based computational reasoning enables consistent and reproducible MTA assignments, with the potential to identify patients who are most likely to benefit from precision oncology compared to standard chemotherapy.

We look forward to engaging with the oncology community in Korea and advancing the conversation on how computational reasoning can help bring precision medicine to the clinic.

09/29/2025

Most people diagnosed with thyroid cancer hear the same message: “It’s treatable.”

And while that’s often true, it doesn’t mean the journey is simple. Some cases are aggressive. Some don’t respond to standard treatments. And for many patients, the hardest part is not knowing what comes next.

September is Thyroid Cancer Awareness Month, a time to recognize not only the progress in care, but also the real challenges patients face when things don’t go as expected.

At Genomate Health, we’re working to change that, by helping oncologists see the full molecular picture of each case, and supporting them in identifying personalized treatment options when decisions get complicated.
Because no one should feel like they’re out of options, even when things don’t go as expected.

09/26/2025

Air pollution is a leading environmental cause of cancer and its effects are not distributed equally. Communities with fewer resources often face higher exposure and have less access to early detection and personalized care.

At Genomate Health, we believe that environmental health is part of health equity. While we work to support oncologists with better decision-making tools, we’re also contributing to solutions beyond the clinic.

Through our partnership with Evertreen, we’re supporting global reforestation to help restore cleaner air and healthier environments. Learn more about our commitment: https://www.genomate.health/news-article/genomate-health-partners-with-evertreen-to-support-reforestation

Because clean air shouldn’t be a privilege. And neither should precision care.

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http://www.genomate.health/

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