MIT Koch Institute for Integrative Cancer Research

MIT Koch Institute for Integrative Cancer Research Bringing MIT’s scientists and engineers together to advance the fight against cancer.

The Koch Institute for Integrative Cancer Research, a National Cancer Institute-designated Basic Cancer Research Center, is the hub of cancer research on the MIT campus. Bringing together biologists, chemists, engineers, computer scientists, clinicians, and others in a state-of-the-art facility, the Koch Institute offers fresh perspectives and interdisciplinary approaches to advancing the fight against cancer. Koch Institute investigators are focused on five research areas that are believed to be critical for rapid progress toward controlling cancer: nanotechnology-based cancer therapeutics, detection and monitoring, metastasis, precision cancer medicine, and cancer immunology and immunotherapy. Working within the vibrant MIT research community and with external collaborators, including NCI-designated clinical cancer centers and biotech/pharma partners, the Koch Institute is dedicated to developing novel insights into cancer, as well as new tools and technologies to better detect, treat, and prevent the disease.

The Anderson and Langer Labs are using machine learning to accelerate lipid nanoparticle design. By evaluating 1.6 milli...
12/12/2025

The Anderson and Langer Labs are using machine learning to accelerate lipid nanoparticle design. By evaluating 1.6 million lipids in silico, they identified promising formulations for mRNA delivery to the lungs, advancing gene therapy development. https://mit-ki.org/3XGLIaP

Ankyra has dosed its first patient with ANK‑101, an anchored IL‑12 drug conjugate originally engineered in the Wittrup L...
12/10/2025

Ankyra has dosed its first patient with ANK‑101, an anchored IL‑12 drug conjugate originally engineered in the Wittrup Lab and former Irvine Lab with support from KI trainee fellowships and the Marble Center for Cancer Nanomedicine. ANK‑101 will be tested in combination with checkpoint blockade immunotherapy for lung cancer patients. Read more: https://mit-ki.org/4rG6iFY

Congratulations to Paula Hammond on being named MIT’s Dean of Engineering!For Paula, this is the latest step in a highly...
12/09/2025

Congratulations to Paula Hammond on being named MIT’s Dean of Engineering!

For Paula, this is the latest step in a highly distinguished MIT career in which she has been an undergraduate student, graduate student, faculty member, department head, Institute professor, vice provost, and executive vice provost – enriching the MIT community with each step she took. She will be the first woman to hold the role of dean of MIT’s School of Engineering.

This next chapter comes at a pivotal moment, and we’re fortunate that she will be bringing her vision and steady leadership to guide the School of Engineering forward.

https://news.mit.edu/2025/paula-hammond-dean-school-engineering-1205

12/05/2025

Please join us in celebrating Hertz Fellow Constantine Tzouanas, who recently completed his doctoral work at Massachusetts Institute of Technology (MIT). 👏 🎓

Tzouanas's research focuses on how tissues emerge from the coordinated behavior of individual cells—and how disease develops when those networks break down. Using sophisticated single-cell and multi-omic approaches, he uncovered key interactions and regulators that drive tissue function and dysfunction. His work is helping reveal the fundamental rules that govern healthy and diseased tissues, laying the groundwork for future advances in diagnostics and regenerative medicine.

Constantine is now continuing this research as a Biswas Fellow in the Bhatia Lab at MIT within the MIT Koch Institute for Integrative Cancer Research.

Dial M for modulation: The Galloway Lab has developed DIAL, a platform that allows researchers to fine-tune the expressi...
12/05/2025

Dial M for modulation: The Galloway Lab has developed DIAL, a platform that allows researchers to fine-tune the expression of synthetic genes even after they have been delivered to target cells. Published in Nature Biotechnology, this work enables more uniform and stable control of gene expression—opening the door to gene therapies precisely tailored to individual patients or cell populations.
https://news.mit.edu/2025/new-system-can-dial-expression-synthetic-genes-up-down-1013

Congratulations to Ram Sasisekharan (Ram S.) on the accelerated FDA approval of the drug sibeprenlimab for treating IgA ...
12/04/2025

Congratulations to Ram Sasisekharan (Ram S.) on the accelerated FDA approval of the drug sibeprenlimab for treating IgA nephropathy (IgAN), a disease where the build-up of abnormal antibodies impedes the kidney’s ability to filter wastes and often leads to kidney damage and failure.

Based on work in the Sasisekharan lab and developed by MIT spin-out Visterra (later acquired by the pharmaceutical company Otsuka), the new drug halves the amount of protein present in urine by targeting a ligand known as APRIL. Continued approval depends on trial data confirming the drug slows the decline of kidney function, due in early 2026.

https://endpoints.news/otsukas-anti-april-antibody-gets-fda-approval-for-kidney-disease-igan/

Congratulations to Alice Hall on being named a 2026 Rhodes Scholar! A senior majoring in chemical engineering, Hall work...
11/25/2025

Congratulations to Alice Hall on being named a 2026 Rhodes Scholar! A senior majoring in chemical engineering, Hall worked in the Langer Lab to improve lung viability for transplantation by investigating alveolar-capillary barrier function. At Oxford, she will pursue graduate work advancing sustainable heating and cooling technologies.

https://news.mit.edu/2025/four-mit-named-2026-rhodes-scholars-1115

Cima Lab alum Canan Dagdeviren’s breast-cancer–detecting bra launched into space aboard Blue Origin’s all-female crew. I...
11/18/2025

Cima Lab alum Canan Dagdeviren’s breast-cancer–detecting bra launched into space aboard Blue Origin’s all-female crew. In microgravity, tumor growth accelerates—helping fast-track innovations in early detection back on Earth. https://news.mit.edu/2025/breast-cancer-detection-space-1

Thank you to Dr. David Mutch of Washington University in St. Louis for delivering the Judith Ann Lippard Memorial Lectur...
11/14/2025

Thank you to Dr. David Mutch of Washington University in St. Louis for delivering the Judith Ann Lippard Memorial Lecture in Cancer Research. His insightful talk addressed how far we’ve come—and how far we have yet to go—in understanding and treating endometrial cancer.

The Judith Ann Lippard Memorial Lecture honors the memory of Judy Lippard, who passed away from endometrial cancer in 2013. This lecture, established by her family, celebrates Judy’s remarkable love of life and her enduring legacy.We’re grateful to all who joined us to celebrate this event.https://mit-ki.org/427vz1g

A new Yilmaz lab study, published in Nature, shows that a cysteine-rich diet may help regenerate the intestinal lining b...
11/12/2025

A new Yilmaz lab study, published in Nature, shows that a cysteine-rich diet may help regenerate the intestinal lining by activating an immune signaling pathway that supports stem cell–driven tissue repair. The findings may inform healing after radiation or chemotherapy. The research was supported in part by the Koch Institute Frontier Research Program, the Bridge Project, and the MIT Stem Cell Initiative.

https://news.mit.edu/2025/cysteine-rich-diet-may-promote-intestinal-lining-regeneration-study-suggests-1001

Address

500 Main Street
Cambridge, MA
02139

Telephone

(617) 324-7795

Website

http://ki.mit.edu/galleries/about

Alerts

Be the first to know and let us send you an email when MIT Koch Institute for Integrative Cancer Research posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Shortcuts

Share

Share on Facebook Share on Twitter Share on LinkedIn
Share on Pinterest Share on Reddit Share via Email
Share on WhatsApp Share on Instagram Share on Telegram

Category