Onpharma Company

Onpharma Company Onpharma - Making Local Anesthetic Better & More Predictable The Onset System is simple to use and allows the clinician to inject and go right to work.

Onpharma's Onset is a revolutionary buffering system that uses Sodium Bicarbonate to raise the pH level of local anesthetic. Onset makes your local anesthetic reliable, predictable and more comfortable for the patient.

09/22/2025

Onset EZ buffers your local anesthetic in seconds! It's easy to use with no training required. β¬‡β¬‡πŸ‘€πŸ‘€

09/03/2025

We are proud to launch our new Onset EZ Buffering Pen!

08/20/2025

πŸ””THIS WEEK! Come find out what's new! πŸ’―

πŸ”” NJ & NYC dental professionals can earn 6 CEU's! Learn more! ⬇
06/10/2025

πŸ”” NJ & NYC dental professionals can earn 6 CEU's! Learn more! ⬇

06/05/2025

πŸ’₯🦷 Game Changer! πŸ“£ ⬇

Address

123 West Nye Lane, Suite 723
Carson City, NV
89706

Opening Hours

Monday 9am - 5pm
Tuesday 7am - 5pm
Wednesday 7am - 5pm
Thursday 7am - 5pm
Friday 7am - 2pm

Telephone

+18773366738

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Onset Buffering System

Chair side buffering using the Onset system is simple to incorporate, easy to use, and will make your local anesthetic better whether you are using Articaine, Lidocaine, Priolocaine or Mepivicaine.

Because local anesthetic is a key part of so many procedures in the dental office, a long-standing question among dental practitioners has been: How can we make our local anesthetic better? Chemistry lies at the heart of the answer. Local anesthetics begin as alkaline solutions, but manufacturers add hydrochloric acid to lower the pH to around 3.5 (or the same as lemon juice) in order to deliver a multi-year shelf life. However, a long-settled principal of parenteral injections is that an injection should be delivered at a pH as close as possible to the pH of the human body, approximately 7.4.

Onpharma gives dentists their first practical way to buffer the local anesthetic cartridge at chair side toward physiologic pH so practitioners no longer have to deliver an injection having the pH of lemon juice.