North Biomedical

North Biomedical We have developed Nanoretinol®, the 232% more effective retinol.

09/22/2025

Most people quit before it works because irritation kicks in and results never show. changed that. Using breakthrough lipid nanoparticles, it delivers retinol deep into the skin where wrinkles actually form, not just on the surface.

The results speak for themselves. In scientific experiments on human skin, Nanoretinol® was 232% more effective in collagen recovery and 73% more effective in elastin recovery compared to regular retinol. In a clinical trial with women aged 35 to 60, skin became visibly firmer, smoother, and more hydrated in only 56 days. Yes, just 56 days.

No empty promises. No harsh irritation. Only science, proof, and results your skin will truly feel and others will notice.

09/15/2025

Regular often begins with intensity: redness, peeling, irritation. This early reaction makes people believe it is working, but in reality it weakens the skin barrier, causes long-term instability, and leaves results inconsistent. Over time, many are left with a damaged complexion and diminished confidence.

is the result of two years of R&D by a team of PhD-level scientists. The active ingredient is encapsulated inside biomimetic lipid nanoparticles that closely mimic human cell membranes. This nanotechnology improves stability, dramatically increases bioavailability, and ensures a controlled release of retinol into the skin over several hours. The result is a treatment that delivers potency without overwhelming the skin barrier.

The scientific evidence behind Nanoretinol® is clear. In ex vivo experiments using human skin, it was shown to be 232% more effective in collagen recovery compared to conventional retinol. This finding demonstrates that the nanoparticle delivery system not only protects retinol but also enables it to act deeper and more effectively in skin tissue.

Beyond laboratory studies, Nanoretinol® has been validated in a 56-day clinical trial with real subjects. Participants showed visible improvements in firmness, elasticity, and texture, without the common drawbacks associated with retinol such as redness, dryness, or flaking. The clinical results confirmed what the ex vivo science had predicted: a steady and reliable increase in collagen activity translates into real improvements in human skin.

This is not marketing hype or empty promises. It is a steady, clinically supported path to visible results that you can rely on. With Nanoretinol®, you no longer have to accept the “narcissist relationship” cycle of regular retinol. Instead, you gain a treatment proven to deliver consistent, visible improvements in just 56 days, without compromising your skin health.

09/13/2025

Eye creams and neck creams are one of the biggest scams in skincare. You’re paying more for a smaller jar that’s often just a diluted version of your regular products. Brands know regular retinol is too harsh for delicate areas, so they water it down, put it in tiny packaging, and sell it as something “special”.

That problem can be solved with . Its lipid-based nanoparticles mimic your skin cells, so it’s absorbed slowly and gently over 8 hours. Safe enough for face, eyes, and neck, while clinically proven to deliver 232% better collagen recovery than regular retinol.

Why waste money on three jars when one product does it all?

       

09/01/2025

Be honest… how many retinols are sitting in your bathroom drawer right now because you quit after two weeks?

That’s the  #1 problem with conventional  : irritation. Retinol can be effective, but in its standard form only a tiny fraction actually penetrates into the deeper skin layers where collagen is made. Most of it stays stuck in the stratum corneum, the outer layer of dead skin cells, where it can’t do much besides cause redness, dryness, or peeling. No wonder so many people give up before seeing results.

 changes that. Instead of raw retinol, we encapsulate it inside biomimetic lipid nanoparticles, the same kind of lipids that make up your skin cell membranes. This tricks your skin into recognizing the nanoparticles as “self,” so they pass through the barrier smoothly and release retinol slowly over time. That means higher bioavailability and no destructive irritation.

We clinically validated this:
1️⃣ In lab experiments with human skin, Nanoretinol was shown to be 232% more effective than conventional retinol in collagen recovery.
2️⃣ In a controlled clinical trial with 56 people, Nanoretinol delivered its first visible anti-aging results in just 56 days, without the usual redness, peeling, or burning that make people quit.

So if you’ve been burned by retinol before (literally), this is your chance to actually stick with it and see your skin change. No redness. No quitting. Just results backed by real science.

08/31/2025

Less than 5% of regular reaches the layers where wrinkles form. Over 95% stays stuck on the surface. Many brands try to force it deeper by adding alcohols or petroleum derivatives that dissolve the skin’s natural lipids. This breaks apart your barrier, makes it more permeable, but also causes redness, peeling and irritation.

works in a completely different way. It uses biomimetic lipid nanoparticles, the same type of technology used in advanced medical delivery systems. These tiny lipid spheres protect the retinol and carry it through your skin barrier without damaging it. Once inside, they slowly release retinol for up to 8 hours. Apply it twice a day and you get 16 hours of continuous skin renewal, with no redness, no irritation, and a healthy skin barrier. Use it in the morning, apply sunscreen on top, and you can go out and enjoy the sun while your skin keeps renewing itself.

08/30/2025

Did you know that only about 4.3% of the you apply actually becomes bioavailable after 24 hours? This refers to the tiny fraction that makes it into the deeper skin layers where wrinkles form. The rest stays on the surface, often in the outermost dead-cell layer (stratum corneum) and can never reach viable epidermis or dermis where it could have a meaningful effect.

This data comes from a human in vitro study by Yourick, Jung and Bronaugh (2008) in Toxicology and Applied Pharmacology. They exposed human skin samples to a 0.3% retinol formulation in gel and emulsion vehicles. After 24 hours, approximately 1.3% was recovered in receptor fluid while about 3.0% remained in viable skin. Together these sum to about 4.3% bioavailable dose.

In other words, more than 95% of the retinol stays at the surface, rather than penetrating to where it matters. That is why it may feel like retinol is not working for many people.

To compensate for this low pe*******on, many brands add ingredients like petroleum derivatives and alcohols that disrupt your skin’s natural lipid barrier. These ingredients work by causing what’s called lipid mobility: a mechanism that weakens and breaks apart the skin’s protective barrier, making it more permeable. While this allows more retinol to get through, it also strips the skin and increases irritation, adding to the damage retinol can already cause at the surface.

And then there is . It changes everything thanks to nanoparticles that deliver retinol deeply, right where it is needed most, with a non-destructive mechanism.

08/28/2025

Most retinol di*es before you finish the bottle. Nanoretinol is different. Stable for a full year, 232% more effective, and clinically proven for anti-aging results in just 56 days.

*Source: ”Retinoid stability and degradation kinetics in commercial cosmetic products”. Doi: 10.1111/jocd.13852. Epub 2020 Dec 2. PMID: 33206444.

08/27/2025

Sometimes failure is the start of something greater. was born from a project that almost ruined us. Today it’s the proven to be 232% more effective in collagen recovery. Scientifically proven in ex vivo research and tested in an in vivo clinical trial. A biotech accident that became a skincare revolution, now available on northbiomedical.com

The retinol of tomorrow, delivered today.
06/21/2025

The retinol of tomorrow, delivered today.

500 billion reasons your skin will thank you.Nanoretinol® delivers retinol through biomimetic nanoparticles that mimic y...
05/16/2025

500 billion reasons your skin will thank you.
Nanoretinol® delivers retinol through biomimetic nanoparticles that mimic your skin’s own cells — for results that are 232% more effective and far gentler.
No redness. No peeling. Just transformation.
We’re sold out (again), but you can still join the waitlist at northbiomedical.com

When the right ingredients come together, magic happens! 🔬💖 Swipe 👉 to discover the ultimate skincare power couples that...
03/11/2025

When the right ingredients come together, magic happens! 🔬💖 Swipe 👉 to discover the ultimate skincare power couples that work better together!

Which combo is your go-to? Drop a 💬 below! ⬇️

How often should you exfoliate? 🤔✨ It depends on your skin type! Generally, 2-3 times a week is ideal for most skin type...
03/03/2025

How often should you exfoliate? 🤔✨ It depends on your skin type! Generally, 2-3 times a week is ideal for most skin types, while sensitive skin may need just once a week. Consistency is key for that healthy glow! ✨💆‍♀️

Drop your skincare routine in the comments! ⬇️ Don’t forget to tag a friend who needs this reminder! 💆‍♀️💖

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