 
                                                                                                    10/03/2025
                                        Given new clinical research suggesting calming and sleep-promoting effects for Aloysia citriodora (lemon verbena), a new study aimed to assess its behavioural, cognitive, psychological and physiological effects in children exhibiting symptoms of attention deficit hyperactivity disorder (ADHD) at the sub-clinical level.
This exploratory study followed a randomised, double blind, parallel group design, wherein 120 healthy participants aged 8 to 17 years received either 15 mg/kg of lemon verbena extract (LVE) or a matched placebo for 56 days. 
Participants who received LVE reported greater subjective fatigue, defined as reduced energy levels according to the Profile of Mood States subscale, without impairment in cognitive performance (p=0.001), compared to placebo. The authors interpreted this as a “calming/de-energising” effect. 
Parent-rated Conners-3 H/I (hyperactivity/impulsivity) showed a near-significant advantage for LVE (p=0.052). At Day 56 (exploratory pairwise), parent assessed H/I was significantly lower for LVE (p=0.045); child self-reports showed a similar trend (p=0.080).
Main limitations of the trial were that it was underpowered (not enough participants) and had a baseline imbalance: the LVE group had worse mood/behaviour at baseline. Also, the chosen population only exhibited sub-clinical symptoms (not diagnosed ADHD).
No details were provided as to how the lemon verbena dry extract correlated to original starting herb, but it was probably around a 5:1 concentrate. So, the dose for a 30 Kg child would be equivalent to around 2.5 g of leaf.
For more information see: https://pubmed.ncbi.nlm.nih.gov/40251851/                                    
 
                                                                                                     
                                                                                                     
                                                                                                     
                                                                                                     
                                                                                                     
                                                                                                     
                                                                                                     
                                                                                                     
                                         
   
   
   
   
     
   
   
  