07/30/2025
🧬 Blueprint Breakdown: MTHFR
Let's talk about a gene that often gets a lot of buzz — MTHFR (yep, that’s a real gene name!).
This gene plays a major role in how your body processes folate (Vitamin B9) — a key B vitamin that supports cell health, brain function, detoxification, and even hormone balance. Folate is also a player in methylation, a vital chemical process that keeps things running smoothly behind the scenes:
🧠 Neurotransmitter production
💆 Hormone regulation
🧬 DNA repair
🛡️ Detox support
But here’s the twist: not everyone’s MTHFR gene works the same.
👉 If you have the CT or TT version of this gene (instead of the CC "wild type"), your body may have a 30–70% reduction in its ability to convert folate into its active form.
💡 What helps?
✨ Methylated folate (like L-5-MTHF) supplements — they skip the conversion step and go straight to work.
🥗 A diet rich in B vitamins, choline, and folate from real foods like dark leafy greens, eggs, nuts, seeds, and whole grains.
🚫 Avoid relying on synthetic folic acid alone — it may not be doing much good if your blueprint includes MTHFR variants.
Your body’s ability to detox, balance mood, and stay energized may all tie back to how well this system works and MTHFR is just one piece of the puzzle. Your 3X4 Blueprint looks at multiple genes involved in this critical methylation pathway, giving a more complete picture of what is going on in there.
➡️ Curious if MTHFR is part of your story? A 3X4 Blueprint can help you find out — and I can help you map your path forward. 💙