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A Major Difference, Inc.

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Centennial, CO
A Major Difference, Inc.

A Major Difference is the manufacturer and worldwide distributor of the IonCleanse® ionic foot bath.
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Major Difference provides IonCleanse products in Centennial, CO

11/25/2025

Did you know chronic stress is linked to more than 75% of doctor’s visits each year? And that prolonged stress can actually shift the body’s chemistry, lowering immune function and slowing down natural detox pathways?

Stress isn’t just a feeling. It’s a physiological state that shapes how well the body can heal, repair, and restore.

That’s why supporting the nervous system matters so much. The IonCleanse by AMD helps encourage the body into a parasympathetic state, the mode often referred to as “rest and digest.” This is the state where the body is finally able to repair: where muscles unclench, the mind steadies, and detox pathways open so the body can do what it’s designed to do naturally.

When the body feels safe, it can release what it’s been holding. That’s the real power of supporting your parasympathetic system.

The IonCleanse by AMD is a great way to support your body in handling stress in this age where stressful situations are often unavoidable. Try us out with our 60-day money-back guarantee.

11/18/2025

The IonCleanse by AMD plays well with other modalities. We often get asked what order you should do them in. When pairing with another modality (or multiple) we always recommend that the IonCleanse should be the final step.

So if you wanted to use an infrared sauna and do an IonCleanse session on the same day, for example, we would recommend using the sauna first followed by the IonCleanse. The thinking here is that other modalities typically help stir up toxins, and the IonCleanse is the only device that acts like a “pull.”

What’s your favorite modality pairing? Tell us about it in a comment.

11/11/2025

We love hearing from IonCleanse practitioners on what a big impact detoxing with the IonCleanse systems can have. On their clients, and on their business. Did you know the IonCleanse by AMD pairs beautifully with almost any other modality? It makes it the perfect addition to any wellness practice.

11/03/2025

“Your body detoxifies itself.”

We hear this a lot. Thing is, we agree! We believe the body knows best, especially in terms of what it needs to release.

But here’s the thing… our body wasn’t ever meant to deal with the levels of toxicity exposure we have in this day and age. In the realm of personal care products alone: a study at Rutgers University found that participants used on average 14.5 personal-care products daily (soap, shampoo, lotion, makeup, etc.), and were exposed to “more than 100 chemicals a day.” And that’s ONLY concerning their personal hygiene products.

WOAH.

So how do you keep up? Detoxing is equally as important in a wellness routine as healthy, clean eating and exercise. And the best part of detoxing with the IonCleanse by AMD is that it keeps your body at the steering wheel.

After an IonCleanse session, the user continues to detox at an accelerated rate for up to 5 days after the cleanse. This happens through an increase of detox in the body’s typical detox pathways (urine, stool, sweat, etc). Which means it’s still your body making decisions on how to facilitate detox.

What detox questions do you have?

10/23/2025

Ever wonder why you feel so refreshed after a walk by the ocean or a waterfall? It’s all thanks to negative ions: tiny, naturally occurring molecules that help the body feel relaxed and balanced.

The IonCleanse® by AMD mimics this natural process by using water, salt, and a gentle electrical current to generate those same feel-good ions, only amplified.

The filtered current delivered by the IonCleanse helps your body enter the parasympathetic state, also known as rest and digest. This nervous system state is where your body is able to detox. As your body relaxes during a session, the ions help attract and draw out oppositely charged toxins through your feet into the water.

We take pride in the fact that we’re nature-inspired while also being cutting-edge. Using the IonCleanse by AMD is like bringing the benefits of nature’s most rejuvenating places right into your home while adding an immense detox benefit. Try it today and put our 60-day money-back guarantee to the test.

10/17/2025

Every body tells its own story after detoxing. For some, it’s deeper sleep. For others, it’s steady energy, clear focus, or simply feeling lighter.

We’ve heard these results for years, and we never get tired of them.
 Experience your own results with our 60-day money-back guarantee. Or, connect with a local practitioner with the practitioner locator on our website to begin your detox protocol.

We can’t wait to hear what results you personally experience.

10/10/2025

Somewhere along the way, we started believing that taking care of our bodies had to hurt; that detoxing meant deprivation, green juice fasts, or sweating it out until we collapse. But the truth is, the body doesn’t need to be forced into balance. It needs to be supported.

Detoxing can be gentle. It can be as simple as slowing down, choosing nourishment over restriction, and remembering that care and discipline aren’t the same thing. Every choice you make for your body can come from love, not lack.

That’s why the IonCleanse by AMD was designed to be the world’s gentlest detox system. Our system is proven through research to increase the body’s ability to naturally release impurities for up to 5 days after each session. It works with your body, not against it, keeping your system in the driver’s seat, where it belongs.

10/02/2025

Skepticism is welcome here. In fact, many people that now work for AMD started out as skeptics.

Here are some of the most common things we hear from skeptics:

1) Wait… so you’re actually detoxing into the water? Why does the water change without feet in it, then?

Yes, you really do detox into the water! We know this because a study showed the presence of urea, glucose, and creatinine molecules in the bathwater after the IonCleanse by AMD was used; organic materials that could only have come from the users’ body.

But you’re right, the water does still change color even if feet are not present in the water. This is because the charged ions generated in the water don’t play favorites and will neutralize anything in the water source, as well. We have more information about this and a video with and without feet on our profile.

2) Why don’t you have more studies on what‘s in the water?

We are WAY more interested in the detox reaction that happens *after* the foot bath. Since the current of the machine stimulates the body’s parasympathetic state, the body continues to detox at an accelerated rate for up to 5 days after the cleanse. This has been the focus of the most recent research efforts, as we believe this is where the biggest benefit from cleansing occurs. And the research is showing that all of the time, including in the most recent study which took a microscope to blood cells before and after cleansing, showing a remarkable difference after only one cleanse. Check it out on our website (there’s a link in our profile.)

3) Is it safe? We’re mixing water and electricity here!

GREAT question, and we almost with we got this one more! Yes, the IonCleanse by AMD is the safest footbath on the market. We’ve been in business for over 20 years, with FDA safety testing, thousands of practitioners, and millions of sessions completed worldwide with no safety complaints. It’s gentle, non-invasive, and safe for nearly all ages.

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We will never discourage skepticism and welcome all questions – let us know what we can answer for you in a comment below.

09/25/2025

What is the difference between the Solo and the Premier?

One was developed for at-home use, and the other was developed for professional use. But we have people in both categories using both machines.

So, which one is right for you? Take a scroll through these slides and we’ll walk you through the differences, so you can make the best choice for you.

Do you have the Solo and realize you’re ready for the Premier? No worries. We have a trade-in program available. Send us a message for the link to apply.

Address

7318 S Revere Pkwy #B7
Centennial, CO
80112

Opening Hours

Monday	8am - 5pm
Tuesday	8am - 5pm
Wednesday	8am - 5pm
Thursday	8am - 5pm
Friday	8am - 5pm

Telephone

+13037550112

Website

http://amajordifference.com/

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