True DNA Story

10/05/2022

Why the most popular Female Breast Cancer DNA tests are terrible
Let’s start with how your DNA is gathered, processed, and analyzed.
It takes specialized equipment and people to extract DNA and get it analyzed.

To save costs, some brilliant people invented ‘Microarray Panels.’ These chemically programmed chips are designed to interact with genetic variants. Each variant must be programmed into the chip.

They are very accurate for variants for which they are designed, but have severe limitations. If the variant you want isn’t programmed into the chip, you can never know.

Microarrays are used by the most popular tests because they are very, very cheap to produce, and give results quickly. What information they give can be accurate, but what about what they do not have? That could mean life or death – literally.

Because of this we have coined the phrase ‘Genutainment.’ It is really genetic entertainment. Go read many of the reports on many ’health’ related tests. They have more disclaimers than they have actual results. Instead, we choose to analyze every single gene and genetic variant – and we store them all forever.

Look at Female Breast Cancer. Everyone has heard of the famous BRCA1, and BRCA2 genes that Myriad Genetics tried (and failed) to patent. That didn’t keep them from capitalizing on these and offering ‘solid’ genetic tests around these genes. Since they are well-known, you have a fairly good chance of insurance paying for it. Millions and millions of dollars are spent on their test, also on 23andMe’s, every year. We feel the data is woefully lacking when it comes to your health.

Even until March of 2020, Myriad Genetic’s Breast Cancer test only covered BRCA1/BRCA2 genes, and the cost? $2,436.00. What about the other genes implicated in Breast Cancer?

That is from their form that was valid until March of 2022.

Fast forward to 2022:
Directly from Myriad’s website:
Integrated BRACAnalysis®: Analysis of BRCA1, and BRCA2 for susceptibility to Hereditary Breast and Ovarian Cancer syndrome.

The total number of genes Myriad covers for breast cancer is now 12. A vast improvement.

Now imagine: True DNA Story analyzes 14 genes and over 980 genetic variants – and always has. We store data on over 700 genes for Breast Cancer.

We didn’t want every woman to think they had Breast Cancer so we pared those 700 genes to the critical 14 according to the NIH, NCBI, and the Royal Academy of Science. For Female Breast Cancer, True DNA Story analyzes, and reports on every gene allowed by the FDA against fully curated data. We constantly research all the major global databases to ensure your reports up-to-date. The neat part is that when science curates more data, we already have the results ready to report on. We re-run your reports free for life, and send you an email to let you know there might be changes.

Welcome to the True DNA Story family.
Know your Story, change your Life.

10/04/2022

October is ‘Breast Cancer Awareness’ month. Well, we want to take it a huge step further. We want to make it Women’s Health Initiative month. Why? Because women’s health is SO MUCH MORE than just Breast Cancer.

There are three major things that affect your health and your life, in this order:
1. Your DNA
2. Your Diet
3. Your Environment

Why is your DNA #1? Because it *is* ‘you.’ It affects everything you think, do, say, and are. It affects how you react to what you eat, how you interact with your environment.

Why is food #2? Although your environment greatly affects you, if you starve to death, it really doesn’t matter. Did you know your DNA affects how well you absorb, or do not absorb nutrients? This also ties heavily into your gut microbiome, but that is a future discussion.

From the time you are a newborn until death, your food is the major determinant on body growth, ability to fight disease, pain, stress, and a host of other things. Your food, combined with your DNA, greatly affects how your body can adjust to your environment – either helping or hindering.

The Environment: The final piece is how your DNA combined with your food can even go so far as to affect how your body reacts, or doesn’t, to drugs, pain, sadness, stimulation, and happiness or joy. Knowing what you should do can help you manage your environment.

Here is a question to ponder: Did you know that many of the same genes tied to Female Breast Cancer are also directly tied to:
· Cervical Cancer
· Ovarian Cancer
· Uterine Cancer
· Vulvar Cancer
· Polycystic O***y Syndrome (PCOS) and
· Endometriosis.
If you are at a high risk for one of these, you should be watching for risk signs for the others.

Why aren’t all the DNA testing companies telling you this? Good question. The most popular DNA tests on the planet are terrible when it comes to helping you manage your health. As an example, for Breast Cancer they check two (2) genes and three (3) genetic variants…of the 981 genetic variants we check tied to breast cancer. And we are the only company that tests for all of them, for every single one.

That is why we are calling October Women’s Health Initiative Month. It is all about educating and empowering women to manage their health.

Welcome to your True DNA Story. We chose that name very carefully. We treat everyone like family because we feel that you are. We analyze every genetic variant you have in every one of your genes to give you your complete, True DNA Story.

Know your Story, change your life.

11/26/2021

Women, you’ve been lied to!!!

OK, now we have your attention. What was the lie? You’ve been told that a serious medical condition (breast cancer) can be diagnosed from a single point mutation in a single gene. Simply not true. We all know that women are extremely advanced, complex beings. So are women’s health conditions. In order to keep this “simple”, we’ll stick to the breast cancer discussion. But these truths are nearly universal and apply across the entire world of healthcare.

First, BRCA1 and BRCA2 are what are called “Tumor suppressors”. They cause infected cells to stop growing and die. They do a few other things as well, but that’s their main function. So, a variant in either gene will impact the protein expressed by that gene, and the effect it has on your system. But there are 4 other tumor suppressor genes involved in breast cancer. What about them? Anybody check those?

Then BRCA1 is 125950 molecules long. BRCA2 is 84792 molecules long. Don’t some of those other molecules matter? They do. Anybody check them?

OK, so what else? A tumor of any kind needs several factors to go wrong at the same time in order to develop. First, a set of messed up tumor suppressors. OK, we have the BRCA genes.

Now what? Second, a cell growth gene has to be messed up so it tells that particular cell to grow out of control. Which ones are those? A bunch that include TP52, PTEN, and about 12 others. Any one of these can contribute to the issue.

Anything else? Yes. There are some genes called “ONCOGENES”. These genes encode proteins that are involved in the control of cell growth. Alteration of the structure and/or expression of protooncogenes can activate them to become oncogenes capable of inducing in susceptible cells the neoplastic phenotype.

What does that mean? It means that these genes, when modified by variants, create an immediate risk of developing a tumor.

What are the ONCOGENES you ask? There’s quite a list. Here are a few to look for. EFGR, KRAS, NRAS, HRAS, MET, RET, MDM2 2 and a bunch more. You don’t need them all. Any one will do the damage. Does anybody even look at these?

So, now you know at least part of the truth. Check True DNA Story to learn more. And if you decide to order before Sunday, use the coupon NOMORELIES for a nice discount. Even if you’re not looking for women’s health issues. There’s a lot more to be found at True DNA Story.

09/03/2021

When we started this journey 4 years ago, we spent 6 months researching the most prevalent and crippling cancers, as well as the most common and debilitating conditions. From that we created the MyAll panel. It covers 90% of all major cancers, and over 80% of all major clinical conditions.

We have since expanded greatly. Instead of just over 50 conditions, we are now well over 160 and over 40 more to be added soon with the Allergy, Connective Tissue, and the Health and Wellness (that includes vitamins, minerals, and foods).

Because of this, the MyAll panel will be renamed to MyEssentials. Hopefully this answers some questions people have had.

All part of our absolute commitment to constant improvement and adaptation. Nearly all the new panels have come from client requests.

Oh, and the Health and Wellness will cover things like:
Vitamins A, B1, B2, B3, B4, B5, B6, B7, B8, B9, B10, B11, and B12 (many people have never even heard of several of those).
Minerals: many such as Calcium, Iron, Selenium, Zinc, Potassium, etc.

Then we will get deep into foods - and how your DNA says you are 'absorbing' or 'using' these. This will tie heavily into the Allergy panel. Many people eat foods thinking they are good for them - but they are actually allergic at some level. My son learned this the hard way with Milk. He loves it, but he isn't just lactose intolerant (which is one of our tests), but fully allergic to milk (also included).

Stay tuned. Lots more coming!

08/06/2021

Some variants or combination of variants make it more or less likely you will manifest a condition.

08/03/2021

There are so many people who have unexplained symptoms or unsatisfactory "diagnosis". What is your DNA holds the answer? What are your genes hiding? True DNA Story analyses every gene and every variant for over 160 conditions.

07/08/2021

Connective Tissue and Allergy Panels will be available by 16 July 2021. Stay in touch for more details.

06/24/2021

Our latest KSL article - using your HSA/FSA to pay for your True DNA Story test. But it is only important if you want to be proactive instead of reactive with your health. Our special promotional price ends on June 30th. https://www.ksl.com/article/50184602/a-comprehensive-dna-test-may-be-free-for-you-and-the-information-in-your-test-could-save-your-life

The results of this DNA test are considered clinical-level and are designed specifically to be discussed with medical professionals.

05/07/2021

We had to force KSL to take down the article posted last night. They used a word the FDA does not like: 'Disease'

Instead go here: https://www.ksl.com/article/50149121/this-dna-test-could-possibly-change-your-life

This is all about life - Beating fear with Hope.

Enjoy.

05/07/2021

Women's Health Initiative has begun.

Did you know that many of the genes that are indicated for Breast Cancer are also implicated in Uterine, Cervical, Ovarian, and Vulvar Cancer, along with Endometriosis and Polycystic O***y Syndrome? It also affects some neurological conditions and some intestinal related ones as well.

Nobody else tests for all these (and we cover over 100 more conditions). We want women to be aware and Beat Fear with Hope. Knowing your Story can change your life.

See our latest here: https://www.ksl.com/article/50161284/4-womens-health-diseases-you-could-develop-based-on-your-genes

If you ask anyone who's suffering or has suffered from a preventable disease, they would probably tell you they wish they could've done more to stop it.