05/08/2024
How Does Semaglutide Produce Its Impressive Weight Loss Results?
Semaglutide the physiological activity of a peptide hormone known as glucagon-like peptide 1 (“GLP-1” for short). Semaglutide has a 94% similarity to naturally-occurring GLP-1 and high bioavailability, meaning that it is very active in the body.
Normally, L-cells, specialized bodies in the gut, produce GLP-1 and release it in response to food intake. In turn, GLP-1 stimulates insulin release, the hormone primarily responsible for shutting blood sugar into the cells for usage and storage, as well as to promote satiation (feelings of “fullness” to signal the body to stop eating).
The scientific literature shows that synthetic GLP-1 (for example, in the form of Semaglutide) combats obesity:
“Synthetic glucagon-like peptide-1 (GLP-1) analogues are effective anti-obesity and anti-diabetes drugs. The beneficial actions of GLP-1 go far beyond insulin secretion and appetite*, and include cardiovascular benefits and possibly also beneficial effects in neurodegenerative diseases.”
Through this mechanism of mimicking GLP-1, Semaglutide produces weight loss in two key ways:
GLP-1 controls blood sugar (blood glucose) and, in response to food, it stimulates insulin release.
GLP-1 effectively reduces appetite.
Weight loss protocols are particularly effective when paired with the low-carb, whole foods-based Semaglutide diet. The experts at Semaglutide For Weight loss advise patients on what foods to enjoy and which to avoid to achieve optimal results.
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