Lighthouse Instruments

Lighthouse Instruments Solutions for Container Closure Integrity testing, Oxygen monitoring, Moisture determination and Media fill inspection.

LIGHTHOUSE offers complete solutions for headspace Oxygen Monitoring, Container Closure Integrity Testing, Moisture Determination and Microbial Contamination inspection of media vials. Our solutions include feasibility studies, process and packaging studies, method development, method validation protocols, automated or benchtop lease platforms, on-site trouble shooting and support. Rapid, nondestructive, laser-based headspace analysis is suitable for applications specific to the sterile pharmaceutical industry. It is a useful analytical tool to generate statistical process and product data in all stages of the product life cycle, from Development to Manufacturing and Quality Control. LIGHTHOUSE Instruments is the leading provider and manufacturer of headspace analysis platforms and measurement services. Contact us for a free demo, feasibility study, or other information.

✨ A few highlights from our Headspace Applications Day Workshop at our Amsterdam headquarters!Our participants explored ...
11/20/2025

✨ A few highlights from our Headspace Applications Day Workshop at our Amsterdam headquarters!

Our participants explored essential topics like container closure integrity, oxygen monitoring for sensitive pharmaceuticals, media fill inspection, deep-cold storage CCI, and moisture analysis. They also gained hands-on experience with headspace analysis.

A special thank you to our invited speaker, Dr. Kevin Ward from Biopharma Group, for bringing valuable insights to the session.

Stay tuned, dates for our 2026 Workshops are coming soon!

11/19/2025

💡 This animation introduces a modern alternative to traditional dye ingress testing: Combining the use of a tracer gas with non-destructive headspace analysis. The video follows a step-by-step visualization of how vials are placed in a container closure integrity test vessel filled with CO₂ tracer gas.

A leak in one vial allows gas to enter, which is later detected by a high-precision LIGHTHOUSE headspace analyzer.

The measurement clearly identifies which vials have failed and it offers a sensitive and analytical approach to container closure integrity testing.

Explore more on our website ➡️ https://lnkd.in/egQQ79jq

11/13/2025

This animation introduces a modern alternative to traditional dye ingress testing: Combining the use of a tracer gas with non-destructive headspace analysis.

The video follows a step-by-step visualization of how vials are placed in a container closure integrity test vessel filled with CO₂ tracer gas. A leak in one vial allows gas to enter, which is later detected by a high-precision LIGHTHOUSE headspace analyzer.

The measurement clearly identifies which vials have failed and it offers a sensitive and analytical approach to container closure integrity testing.

Learn more ➡️ https://lighthouseinstruments.com/applications/container-closure-integrity-testing-ccit/replace-dye-test/?utm_source=LinkedIn&utm_medium=socialmedia+&utm_campaign=ccit

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We’re excited to be part of CPHI & PMEC India in partnership with Spinco Biotech. 📅 25–27 November 📍 Booth 12.B33Don’t m...
11/12/2025

We’re excited to be part of CPHI & PMEC India in partnership with Spinco Biotech.

📅 25–27 November
📍 Booth 12.B33

Don’t miss the opportunity to meet our team, Josephine Bouwman and Dr. Jim Veale and discover how LIGHTHOUSE’s non-destructive headspace analysis solutions can help support and accelerate your business.

See you in India!

Greetings from South Africa!Day 1 at the A3P Association /BASAN Cleanroom Forum.Our expert Dr. Giovanni Auricchio, PhD, ...
11/11/2025

Greetings from South Africa!
Day 1 at the A3P Association /BASAN Cleanroom Forum.
Our expert Dr. Giovanni Auricchio, PhD, MBA is here to welcome you at our booth.

Don’t miss tomorrow’s presentation by Dr. Derek Duncan, Lighthouse Instruments and Tyla Potgieter, Aspen Pharmacare.

🗓 Wednesday, November 12
🕦 11:30 AM – 12:10 PM
💡 Case Study: Testing and Control Strategies for Container Closure Integrity

We’re looking forward to connecting with you!

✨ We were glad to participate in the Parenteral Drug Association - PDA Aseptic Filling Congress in Como, Italy! 🇮🇹Dr. ...
11/10/2025

✨ We were glad to participate in the Parenteral Drug Association - PDA Aseptic Filling Congress in Como, Italy! 🇮🇹

Dr. Francesca Caprioli, Lab Director at Lighthouse Instruments, and Alessia Pacioni from Polpharma Biologics S.A., presented an insightful case study:

“CCI Test Method Development and Validation of a Fully Assembled Autoinjector Device.”

Day 2 at CPHI Frankfurt!Another exciting day ahead! Visit our booth to explore how our laser-based headspace analysis so...
10/29/2025

Day 2 at CPHI Frankfurt!

Another exciting day ahead! Visit our booth to explore how our laser-based headspace analysis solutions ensure product quality and process control.

Our team, Avand Amedi, Dr. Marnix Wieffer and Dr. Steven de Vries, is here to meet you and answer your questions about container closure integrity testing, oxygen monitoring, media fill and moisture determination.

We look forward to connecting with you!

Day 1 at Pharma Education Center PEC - Microbiology Congress 2025 ! 📅 October 29.Dr. Giovanni Auricchio, PhD, MBA, is lo...
10/29/2025

Day 1 at Pharma Education Center PEC - Microbiology Congress 2025 !
📅 October 29.

Dr. Giovanni Auricchio, PhD, MBA, is looking forward to meeting you to discuss our headspace analysis solutions for media fill inspection.

Also, don’t miss the presentation by Dr. Francesca Caprioli, Laboratory Director at Lighthouse Instruments:

◾ “Rapid and analytical microorganisms’ detection inside media-filled vials through laser-based headspace analysis, replacing subjective visual inspection.”

See you soon !

10/22/2025

This animation illustrates how headspace oxygen analysis supports stability studies for oxygen-sensitive products in pre-filled syringes (PFS). Over a 12-month period, headspace oxygen levels were non-destructively monitored inside PFS.

The point at which the antioxidant becomes saturated and the API starts to change color was clearly marked by a change in headspace oxygen levels.

Non-destructive headspace analysis generates robust analytical data, offering clear insight into package integrity, oxygen ingress, and product oxidation stability over time.

We’re thrilled to join the PDA - Parenteral Drug Association – Pharma Microbiology Conference in Washington, DC!📅 27–29 ...
10/21/2025

We’re thrilled to join the PDA - Parenteral Drug Association – Pharma Microbiology Conference in Washington, DC!

📅 27–29 October - 📍 Booth #107

Visit us at our booth to meet Dr. Jim Veale and Tom Millner discover how LIGHTHOUSE’s non-destructive headspace analysis solutions can support and accelerate your business.

See you there!

Florence, we’re ready! We’re excited to join the Pharma Education Center PEC - Microbiology Congress 2025! 📅 October 29V...
10/15/2025

Florence, we’re ready!

We’re excited to join the Pharma Education Center PEC - Microbiology Congress 2025!
📅 October 29

Visit our booth #16 to meet Dr. Giovanni Auricchio, PhD, MBA and learno about our headspace analysis solutions for media fill inspection.

Don’t miss the presentation by Dr. Francesca Caprioli, Laboratory Director at Lighthouse Instruments:
◾ “Rapid and analytical microorganisms’ detection inside media-filled vials through laser-based headspace analysis, replacing subjective visual inspection.”

Ci vediamo lì !

✨ SAVE THE DATE – October 21–22, 2025 ✨We’re excited to announce that we will be attending the PDA - Parenteral Drug Ass...
09/25/2025

✨ SAVE THE DATE – October 21–22, 2025 ✨

We’re excited to announce that we will be attending the PDA - Parenteral Drug Association - Universe of Pre-Filled Syringes and Injection Devices Conference 2025 in Vienna, Austria! 📍 Find us at Booth 35.

👉 Meet our experts, Avand Amedi and Dr. Marnix Wieffer, and learn how you can achieve consistent seal quality with fast, non-destructive container closure integrity testing (CCIT). Join us for live demos and explore how our solutions can support your business.

📢 Don’t miss our poster presentations:
🗓 October 21 | ⏰ 15:40 – 16:25

▪️ “Mitigating CCI Risks in PFS Under Deep Cold Storage: A Case Study Using Headspace Analysis” - Presented by our Laboratory Director, Dr. Francesca Caprioli.

▪️ “Determining the Oxygen Permeation Rate through Different Syringes”
Presented by our Analytical Services Consultant, Dr. Marnix Wieffer.

See you there !

Address

2050 Avon Court
Charlottesville, VA
VA22902

Opening Hours

Monday 9am - 5pm
Tuesday 9am - 5pm
Wednesday 9am - 5pm
Thursday 9am - 5pm
Friday 9am - 5pm

Telephone

+31207051050

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