04/14/2025
If I am considering taking any of the bone meds? I want to make sure it's the right one.The wrong one can cause so many side effects, and NOT WORK. This list is in addition to the regular group of 4 that doctors routinely run. I would NOT take a bone med without first having a serious look at labs. They don't ALL need to be run, but they need to be considered.
Labs, labs labs
5. PTH-intact (parathyroid function)
6. Calcium (serum calcium, ionized calcium)
7. 24-hr urine test (calcium and creatinine, to check kidneys)
8. GFR (glomerular filtration rate)
9. Creatinine (CCr or CrCl)
10. Magnesium RBC (best magnesium test)
11. Phosphorus
12. Celiac Profile
13. Hormones (estradiol,free testosterone, SHBG DHEA, progest)
14. Cortisol
15. Homocysteine
16. HS-CRP (high-sensitivity C reactive protein)
17. Bone Activity Markers
Bone Building/Losing?, if so, how fast? repeat 6-12 mos)
*osteocalcin
*Bone Specific Alkaline phosphatase
* PINP (pro collagen type 1 N-terminal propertied)
Bone Resorption Markers (urine tests):
*NTx (collagen type 1 cross-linked T telopeptide, serum or urine)
*CTx (collagen type 1 cross-linked C telopeptide, serum/urine)
* DPD (deoxypyridinoline cross links, urine. < accurate, do later)
18. ESR (Erythrocyte sedimentation rate, for inflammation, which eats bone)
19. Prolactin
20. Protein Electrophoresis (r/o multiple myeloma)
21. Calcitriol (1,25 dihydroxyvitamin D or 1,25 (OH)2D Test? Kidney
function, Test for parathyroid func, hypercalcemia
22. Lipid Peroxides and 8OH2dG23. Lipoprotein A (seldom checked, new, very important)
24. ELISA Enzyme Linked Immunosorbent Assay (must be taken pre
Evenity)
25. Bone Specific Alk Phosphatase (rule out genetic bone disease)