JAMA Surgery

10/30/2025

Robotic hiatal hernia repair offered no short-term morbidity or mortality advantage over laparoscopic hiatal hernia repair but incurred longer operative times and a higher pulmonary embolism risk in older adults. https://ja.ma/4oHKwiX

10/30/2025

Pediatric liver transplant recipients who lose Medicaid coverage at age 19 experience a marked decrease in both short- and long-term survival compared to privately insured peers. https://ja.ma/47xO2FN

10/29/2025

Retrospective application of DELTA methodology to a large inguinal hernia mesh database identified safety signals for select mesh brands, suggesting continuous, automated monitoring can inform device selection and regulatory scrutiny. https://ja.ma/3X2xe4G

10/28/2025

Loss of independence (LOI) and associated factors like frailty and postoperative delirium are linked to increased mortality risk in older adults undergoing emergency general surgery. https://ja.ma/47iz6fD

10/27/2025

ARTx-Onc is the largest reported cohort of liver transplant recipients for colorectal liver metastases and remains the only multicenter registry focused on oncologic outcomes in this population. https://ja.ma/4qmOwam

10/26/2025

Large language models ( ) can simplify surgical instructions to a similar readability level as human-simplified versions while maintaining fidelity, though physician oversight is necessary. https://ja.ma/48WP28A

10/25/2025

Hosting an a**l cancer screening unit at an LGBTQ+ community event effectively raised awareness and provided screening opportunities for men and transgender women at increased risk. https://ja.ma/476GHN5

10/25/2025

Matched suba**lysis found no benefit in percent total body weight loss for preoperative -1 RA use vs controls at 12 months after bariatric surgery, suggesting the effect of these agents may be limited postoperatively.

https://ja.ma/48GeEXg

10/24/2025

Systematic review: This a**lysis identified 50 evidence-based recommendations for managing mental disorders in traumatic injury patients, with a focus on traumatic brain injury. https://ja.ma/4he5fsi

10/24/2025

GLP-1 agonists are not cost-effective compared to gastric bypass for patients with severe obesity if current drug pricing persists, with an incremental cost-effectiveness ratio exceeding $500,000 per QALY over 10 years. https://ja.ma/48JocAT

10/23/2025

Increasing the use of pragmatic clinical trials in surgery could address the challenges of conducting RCTs by optimizing generalizability, standardizing data use, and encouraging surgeon participation. https://ja.ma/3IQH7iD

10/23/2025

Low-risk CP-GEP test results were associated with a 7% SLN positivity rate, while high-risk cases had a threefold higher risk—supporting value for shared patient-surgeon decision-making in T1-T3 melanoma.

This prognostic study investigates if a gene expression profile–based test can predict sentinel node status in patients with tumor stage T1 to T3 melanoma precisely enough to inform decision-making.