10/07/2025
Jessica Lopez was diagnosed with leukemia and retinoblastoma (a rare type of eye cancer) as a child, which left her blind. Years of chemotherapy treated the cancers but caused lasting health complications.
In November 2023, while newly engaged to be married, Jessica learned she needed both a heart and a liver transplant. She was in heart failure due to cardiomyopathy, a disease that weakens the heart muscle, and the damage had impacted her liver.
She waited a year on the transplant list, but during that time, her condition worsened and began to affect her kidneys. Jessica now needed three organs: a heart, a liver and a kidney.
Triple-organ transplants are extremely rare — only 59 heart-liver-kidney transplants have ever been recorded in the United States. One of those had been performed by the teams at Northwestern Medicine Bluhm Cardiovascular Institute and the Northwestern Medicine Organ Transplant Center, and they were determined to do it again to help give 32-year-old Jessica a second chance at life.
Because all organs need to come from the same donor for triple-organ transplants, the wait time can be long, but on February 24, 2025, three organs became available. Jessica’s heart and liver were transplanted together, and then a separate team of surgeons performed her kidney transplant.
Today, Jessica, who has been in remission from cancer for 20 years, is now thriving with her new heart, liver and kidney. “I feel like I was reborn,” says Jessica. “I’m grateful for my organ donor and their family. I’ve been given a second chance at life and can start planning for my future.”
Jessica and her fiancé are now looking ahead to their 2026 wedding in California.