
27/07/2025
After a decade of diligent progress, a new drug from UI Health — biologic eyedrops to treat dry eye disease — will proceed to clinical trials this summer 👀
Dry eye disease is an umbrella term for conditions that cause chronic pain, itchiness, inflammation, and overall eye discomfort.
Several immune signals switch on simultaneously to trigger dry eye, each traveling down its own biological route to inflame the eye’s surface. Because today’s drugs typically target only one route, the unchecked pathways can continually irritate the eye. Fuller relief often depends on treatments that calm multiple signals at once.
The new drug is composed of antibodies, consolidated from more than 8,000 healthy participants. Administered in the form of eyedrops, the biologic drug shuts off multiple inflammation pathways at once.
“It’s not just one drug. It’s a collection of natural antibodies with myriad actions against inflammation,” said Dr. Sandeep Jain, a UI Health ophthalmologist who directs our Dry Eye and Ocular GVHD Clinic. “It’s like using a hair clipper versus cutting your hair strand by strand.”
Learn more: https://bit.ly/40u158y