01/22/2026
announcement : ORAL WEGOVY (semaglutide pill) — NOW AVAILABLE
• Cost (out of pocket, no insurance): $149/month for the first 2 months. Coupon needed except at pharmacy for members or straight from
• Dose: 25 mg once daily (oral) maintenance but 1.5mg to start
• Indication: Chronic weight management (with nutrition + lifestyle support)
How to take (this matters):
• Take first thing in the morning on an empty stomach
• With ≤4 oz water only
• Wait 30 minutes before food, drinks, or other meds
• Swallow whole — do not crush or split
Effectiveness:
• Oral semaglutide achieves weight loss comparable to injectable Wegovy
• Average weight loss ~13–15% in trials
• Works by reducing appetite and increasing satiety
• Results are best with adequate protein + resistance training
Side effects (similar to injections):
• Nausea
• Reflux/heartburn
• Constipation or diarrhea
• Decreased appetite
• GI symptoms are most common during dose escalation
Key differences vs injections:
• Oral form has lower bioavailability, so timing and fasting are critical
• More day-to-day adherence required
• No needles, no refrigeration
Bottom line:
Same medication. Different delivery.
Real benefits, real side effects, and needs proper medical oversight.