02/23/2026
Is TRT Bad for Your Heart?
Short answer:
When prescribed appropriately and medically monitored, current evidence does not show an increased risk of heart attack or stroke in men with clinically low testosterone.
For years, there was concern. But more recent, high-quality research has provided reassuring data.
In the large 2023 TRAVERSE trial published in the New England Journal of Medicine, researchers found that testosterone therapy was noninferior to placebo for major adverse cardiovascular events in men with confirmed hypogonadism and elevated cardiovascular risk.
The U.S. Food and Drug Administration also reviewed newer cardiovascular outcomes data and updated safety communications based on more current evidence.
Here’s what matters:
✔ Appropriate patient selection
✔ Physiologic dosing
✔ Ongoing lab monitoring
✔ Medical supervision
Unmonitored, supraphysiologic steroid use is not the same thing as medical TRT.
Low testosterone itself has been associated with:
• Increased visceral fat
• Insulin resistance
• Inflammation
• Adverse lipid markers
Optimizing hormones in the right patient, at the right dose, with the right monitoring is very different than abusing hormones.
If you’re experiencing symptoms, the answer isn’t fear.
It’s data.
Know Your Levels at Optimize U.
Want to learn more? Fill out our contact form: https://link.msgsndr.com/sp/25fd02d3444
