Cincinnati Children's Clinical Research Studies

01/13/2026

Caregivers of children and teens 2 to 17 years old with Down syndrome are needed for a research study. In this study, researchers want to create a tool to better measure challenging behaviors in children with Down syndrome. It includes caregiver online surveys, a virtual interview, and structured play sessions for children during in-person visits. Pay is up to $400 for study completion (3 in-person visits and 1 virtual visit).

To see if your child is eligible, go to www.redcap.link/BIDS3 or contact Aine at aine.powell@cchmc.org or dsresearch@cchmc.org or 513-636-3058.

01/09/2026

Advancing food allergy care starts with research—learn more below.

Finding the right care is crucial when your child is diagnosed with a food allergy. That’s why our Cincinnati Children's Clinical Research Studies team is recruiting for a study to see if a specialist infant formula designed for food allergy will be tolerated by infants and children with cow’s milk allergy. We're seeking infants and children 3 months to 12 years old. Approved participants will receive payment. Learn more through the link in the comments.

01/08/2026

We are recruiting Hispanic/Latino teens 13 to 17 years old who are interested in sharing their experiences related to their food environments. This is a study to learn more about food access in Hispanic/Latino teens and identify any unique challenges they may experience in their food environments. Participants may receive up to $275. Possible travel reimbursement may also be provided. For more information, or to see if you qualify, go to www.redcap.link/YIDRA or contact Wendy.DeLaRosa@cchmc.org or 513-516-1111.

01/05/2026

Stories like Sriansh’s highlight why we do what we do—turning hope into reality through groundbreaking research and expert care.

Thanks to an innovative clinical trial at Cincinnati Children's, Sriansh is thriving in unimaginable ways. Through this trial, 16-month-old Sriansh received a one-time gene therapy to treat his rare genetic disorder, AADC deficiency, becoming the youngest child in the world to receive this treatment.

Because of this groundbreaking therapy, Sriansh is now walking, running, and swinging – milestones his family never imagined he’d reach. For more on Sriansh’s : https://bit.ly/4pNtWPK

12/29/2025

Children and teens 8 to 18 years old diagnosed with multiple sclerosis (MS) who do not have dental braces are needed for a study which looks at brain cells associated with inflammation. The study involves an MRI and cognitive testing. Pay is up to $125 for 1 or 2 study visits. For more information or to see if you or your child is eligible, contact Karlee at karlee.migneault@cchmc.org or 513-803-5299.

12/23/2025

When should you use epinephrine (adrenaline)? When is it safe to stay home afterward?

Families dealing with severe allergic reactions (anaphylaxis) have faced confusing advice for years. Now, for the first time, researchers—led by experts at Cincinnati Children’s—have published clear, evidence-based guidelines to help reduce stress and unnecessary ER visits.

✅ Use epinephrine right away for serious symptoms like trouble breathing or swelling.
✅ In some cases, if symptoms improve and you meet safety steps, you may not need to call 911.

Check the second image for key factors for safely staying home after using epinephrine, and visit the link in our comments to learn how this game-changing research can help families make informed decisions.

12/19/2025

Research in action: At Cincinnati Children's, we’re working every day to create better care for kids. We’re proud to share Dr. Ryan Moore’s amazing work using virtual reality to help surgeons plan life-saving heart surgeries. Learn more:

Pediatric cardiologist Ryan Moore, MD, MSc, is using cutting-edge technology to revolutionize how doctors perform heart surgery for children and teens around the world.

Through rigorous research and modeling at Cincinnati Children's, Dr. Moore and his team designed a virtual reality surgical simulation that creates a 3-D digital twin of a patient’s heart. Surgeons around the globe can connect and interact with a patient’s model, enabling more effective treatment plans and improved surgical outcomes.

Thanks to children’s hospitals’ commitment to pediatric research, physician scientists like Dr. Moore are redefining the future of heart surgery and making more moments possible for children and teens. Learn more about pediatric researchers in our new video: https://www.madepossible.org/impact/

12/19/2025

We are recruiting children and teens 12 to 17 years old who have eczema. Participants may be compensated for their time and effort. To learn more, contact adrnstudies@cchmc.org or call or text 513-264-6918.

12/17/2025

We are recruiting infants and children 3 months to 12 years old who are diagnosed with a cow’s milk allergy. Participants will receive up to $800 for their time and effort with possible travel reimbursement. For more information, contact Jennifer at Jennifer.jennings2@cchmc.org or 513-636-7085 or visit our website (link in comments).

12/12/2025

We are recruiting healthy children 10 to 18 years old. This is a study to compare students who are not aggressive with students who are aggressive to shape AI software. Participants may receive $15 for a one-time interview. For more information, go to www.redcap.link/ARiA or contact 513-240-9131 or Alexander.Osborn@cchmc.org.

12/11/2025

Matthew has faced more challenges than most because of a rare genetic disease with no cure. Instead of giving up, he leaned in—becoming the first participant in a groundbreaking clinical trial at our Applied Gene and Cell Therapy Center, part of the nation’s #1 cancer program.

Early results are promising, and Matthew’s courage is helping researchers explore an innovative treatment that could change lives for generations to come.

Clinical research isn’t just science—it’s hope. And Matthew proves every study brings us closer to answers.

👉 Learn more about his journey: https://www.cincinnatichildrens.org/service/b/bone-marrow/patient-stories/matthew-dyskeratosis-congenita

12/08/2025

This investment will accelerate research and improve care for children and families facing life’s toughest battles, bringing us closer to better outcomes through innovation.