Cincinnati Children's Clinical Research Studies

08/07/2025

New findings!
A study led by our experts found promising results for a nasal COVID-19 vaccine — a needle-free option that may offer stronger protection.

The vaccine was well tolerated, absorbed through nasal tissues, and reduced the risk of infection by at least 67% compared to those who’d never been vaccinated.

👉 Check out our Science Blog to learn more about the study and what’s next: https://scienceblog.cincinnatichildrens.org/nasal-covid-vax-shows-promise-in-phase-1-clinical-trial/

08/05/2025

We are recruiting children in middle school who have been diagnosed with autism and their caregiver(s). Participants will receive up to $300 and an 8-weeks intervention program focused on improving academic or social skills at no cost. For more information, go to www.redcap.link/skillsbuilder, or contact skillsbuilder@cchmc.org or 513-636-5994.

08/01/2025

New study for healthy children 3 to 33 months old:

Our Cincinnati Children's Clinical Research Studies is conducting a research study for healthy children 3 to 33 months old. Healthy children play an important role in research by helping us understand how they grow and develop—knowledge that can lead to better care, illness prevention, and healthier futures. Families may receive up to $640 for participating. See if your child qualifies through the link in the comments.

07/31/2025

We are recruiting infants and children 3 months to 12 years old who are diagnosed with a cow’s milk allergy. Participants will receive up to $800 for their time and effort with possible travel reimbursement. For more information, contact Jennifer at Jennifer.jennings2@cchmc.org or 513-636-7085 or visit our website -www.cincinnatichildrens.org/service/c/clinical-trials/studies/cows-milk-allergy-083024

07/23/2025

Children, teens, and adults with a diagnosis of autism and their parents are needed for a research study that can be completed at home. The pay is up to $50. If interested, contact the study coordinator by call or text message at 513-318-7845 or autism@cchmc.org. To learn more, go to www.cincinnatichildrens.org/service/c/clinical-trials/studies/speed-up-autism-research?fbclid=IwAR10tD1dFeguhBl6sUKAdFgkMNTmbQwiwxP5_gF7a5df8eP5x9TIUgj8IcY

07/21/2025

New Research Findings!

A recent study by our experts found that how and when a child wheezes—whether it’s infrequent, persistent, transient, or starts later—can help predict the type of asthma they may develop later in life.

These insights could help doctors tailor asthma treatment, allowing for earlier changes to care and prevention.

🔗 Learn more: https://scienceblog.cincinnatichildrens.org/childhood-wheeze-patterns-linked-to-distinct-asthma-subtypes-later-in-life/

07/18/2025

We are recruiting children and infants 3 to 33 months old who are healthy. Pay is up to $640. For more information, go to www.redcap.link/MPAACHscreener
or contact MPAACH@cchmc.org or 513-803-8000.

07/15/2025

Pregnant women who are at least 18 years old and 34 or more weeks pregnant are needed for a study to learn how moms and babies respond to influenza infections and vaccines. Vaccinations are not required for this study. Pay is up to $3,000 if all procedures are completed. For more information, contact the study coordinator at IMPRINT@cchmc.org or 513-846-2101, or visit www.cincinnatichildrens.org/service/c/clinical-trials/studies/pregnant-women-infants-062624

07/10/2025

Study for children with autism or Fragile X syndrome.
Learn more: https://redcap.link/Entrain

We’re committed to enhancing the lives of individuals with autism spectrum disorder (ASD) and Fragile X syndrome (FXS), and their families, by improving children’s health, quality of life, and long-term outcomes. About two-thirds of people with FXS also have a form of ASD. That’s why our Cincinnati Children's Clinical Research Studies team is conducting a study for children 5 to 10 years old with ASD and/or FXS. The study explores whether listening to different tones and sounds can help improve learning and sensory symptoms in children with FXS. This research could fuel groundbreaking discoveries in ASD and FXS research and care. Learn more and see if your child qualifies: https://redcap.link/Entrain

07/10/2025

Girls 9 to 13 years old and boys 10 to 14 years old who may be at higher risk of developing type 2 diabetes are needed for a study. In this study, we are focused on discovering why some children are more at risk for type 2 diabetes than others. We are inviting families across the U.S. to help us figure this out. You will be compensated for your time. To see if your child qualifies, go to www.redcap.link/discovery or contact the study team at discoveryinteens@cchmc.org.

07/03/2025

🫁 Big step forward in lung research! Scientists at Cincinnati Children’s have grown mini human lungs in the lab—with their own blood vessels.

This helps researchers understand how lungs develop and how rare and life-threatening conditions, like those that cause newborns to struggle to breathe due to malformed blood vessels, happen in the first place.

💡 Why this matters:
• Brings us closer to repairing damaged organs
• Sheds light on rare lung disease in newborns
• Offers clues to healing damage from viruses like COVID-19

This cutting-edge research was led by our experts in our Center for Stem Cell and Organoid Medicine (CuSTOM).

Learn more on our Science Blog: https://scienceblog.cincinnatichildrens.org/first-lung-organoid-with-organ-specific-blood-vessels

06/27/2025

We are recruiting caregivers and teens to take a survey. This is a 2- to 3- minute survey to assess knowledge and awareness of depression and TMS. Participants will have a choice to be entered in a drawing for a $50 gift card for the completion of the survey. For more information, go to www.redcap.link/depressionsurvey or contact Priya Ramesh at priya.ramesh@cchmc.org or 513-636-4433.