HLH Center of Excellence at Cincinnati Children's

Cincinnati Children’s treats a large population of children with HLH. Hemophagocytic lymphohistiocytosis (HLH) is a disorder of the immune system in which too many infection-fighting cells are produced and activated, causing damage to organs. However, with prompt and accurate diagnosis and timely treatment, a cure is possible. Unfortunately, few physicians are knowledgeable about HLH, and it is of

ten misdiagnosed or diagnosed too late. Without access to effective treatment, primarily bone marrow transplantation (BMT), most patients with HLH die. Our physicians and researchers have recently joined forces with families who have faced an HLH diagnosis and philanthropists to create the HLH Center of Excellence. The center focuses on the core priorities of diagnosis and clinical care, research, education and awareness, and family support.