Center for Autoimmune Liver Disease at Cincinnati Children's Hospital

10/28/2025

Share your ideas for this year's symposium!

https://docs.google.com/forms/d/e/1FAIpQLSe4_-uPZHDOTVg5a2WFiHcI8pccOQEoujEFKsmGou5CGnaoPA/viewform

This is your opportunity to inspire, educate, and connect with others who share your passion for improving the lives of children and families affected by autoimmune liver diseases.

Deadline for proposals: January 18, 2026

Event Details: https://www.facebook.com/events/1112954464157632

10/27/2025

Registration is now open! https://cvent.me/Dm9WOZ

09/10/2025

Join the Cincinnati Walks for Kids 20th Anniversary Celebration!

Join the A-LiNK4Hope team in person and virtually to support the work of our patients/families in education, outreach, and advocacy.

Register here: https://giving.cincinnatichildrens.org/team/762879 and participate in person or virtually. The donated funds will directly support A-LiNK’s mission- on the drop-down menu with registration, you will need to specify Gastroenterology/A-LiNK as in the picture.

When: Sunday, September 28th, 2025. Registration opens at 7:30 AM EST, and our walk begins at 9:00 AM EST.

Where: Great American Ball Park, 100 Joe Nuxhall Way, Cincinnati, OH. The 2-mile is stroller and wheelchair friendly. There will be a 1-mile option available.

Why: To be a hero for children’s health!

Register here: https://giving.cincinnatichildrens.org/team/762879

Learn more about A-LiNK’s commitment to children with autoimmune liver diseases and explore resources https://www.aildnetwork.org/

09/05/2025

Join us in supporting the Crohn's & Colitis Foundation's annual gala! It is an evening of celebration and fundraising for a great cause. We are especially proud to announce that our very own Dr. Lee Denson will be honored with the Uniting to Care and Cure Award at the event. Click the link to learn more and get your tickets! https://onecau.se/nightforacure25

Join us at the 2025 special event gala in Cincinnati!To learn more, volunteer, or purchase a ticket/sponsorship, click here: https://onecau.se/nightforacure25.

05/23/2025

A-LiNK Connections just released their Caregiver Coping Resource, a fantastic guide developed with ImproveCareNow’s parent/caregiver group, and Social Workers and Psychologists. It is packed with insights from caregivers of children with Autoimmune Liver Disease (AILD) and Inflammatory Bowel Disease (IBD), as well as supporting professionals. Check it out and share!
Caregiver Coping Resourcehttps://static1.squarespace.com/static/654542910d6d59414d622499/t/68267e36e5ceac462b23048c/1747353209731/Caregiver+Coping+Resource+-+ICN+A-LiNK+-+May+2025+Final.pdf
Patient and Family Education Manual https://static1.squarespace.com/static/654542910d6d59414d622499/t/67095b10fa31ff3f4790b300/1728666396975/A-LiNK+Patient+and+Family+Education+Manual+Vol+I+2024+-+DIGITAL+med+res_.pdf
Get Involved: Patients, Caregivers, Physicians https://www.aildnetwork.org/get-involved
A-LiNK Website: aildnetwork.org https://www.aildnetwork.org/

12/23/2024

07/22/2024

Hello Patients, Families, Friends, and Community members in the Greater Cincinnati Area!

We would like to invite you to a special benefit concert hosted by the Asian American Coalition of Ohio (AACO) in support of CALD’s critical research into autoimmune liver diseases (AIH, PSC, ASC).

The AACO youth leaders have organized an evening of live music, featuring the violin, cello, keyboard, flute, and vocals!

When: Saturday August 3rd, 2024, 6-9 PM
Where: 766 Reading Rd, Mason Ohio 45040 - Cincinnati Chinese Church

Come join us to learn more about CALD’s research, meet other community members, support CALD and the AACO, or just enjoy the music!

Make a Difference: Share your story
Have a story of hope or inspiration you'd like to share? We'd love to hear from you!
Contact us at CALD@cchmc.org and your story could be featured at the event.

Spread the word and help us raise hope for a brighter future!

We look forward to seeing you there!

05/31/2024

A RARE Opportunity!

A day of support and education for PSC children, teens, and their families!

You are invited to attend the Canadian Paediatric PSC Day from the comfort of home!

This Saturday, June 1! 9:50AM EST - 3pm EST

Whether you are Canadian or not, you are invited to join this paediatric-focused webinar, co-hosted by PSC Partners Seeking a Cure and Dr. Amanda Ricciuto from the Hospital for Sick Children, and in partnership with Toronto Centre for Liver Disease and Ajmera Transplant Center at University Health Network!

Register for Webinar Here https://us02web.zoom.us/webinar/register/WN_OdvgGZ5dRbCnIilwr5nppA?fbclid=IwZXh0bgNhZW0CMTAAAR0AogNwXfPddvo_Pt7JHhw_nAlbxLeeBxworREd2Cn8ds6M8SYzD_NTd5c_aem_AQBxSy5iq-AfxvHrPwOooec0x2q-Ate6PHjcFvCdeLYUaAWdr0EQH9xQIynIgBI54nhqIRpZFHGTp8Aj8daY0gs8 #/registration

This event is designed for children and teens with PSC and their families. French and ASL interpretation will be available to online attendees.

We encourage everyone in the PSC community to attend this special event that brings together PSC children & teens, their families, and PSC experts.

Medical Speakers:

Sara Ahola Kohut, PhD - Psychologist and Health Clinician Scientist with the Medical Psychiatry Alliance (MPA) at The Hospital for Sick Children (SickKids) and an Assistant Professor with the University of Toronto. Dr. Kohut’s program of research develops therapies and programs to support the quality of life of children with chronic health conditions and their families. These therapies focus on supporting the physical, emotional, and social health of these children.

Gary Bader, PhD - the Ontario Research Chair in Biomarkers of Disease in the Department of Molecular Genetics. His research focuses on systems biology at the cell and tissue level. He is also a Professor at The Donnelly Centre at the University of Toronto and an expert in Computational Biology. Dr. Bader is Principal Investigator on a four-year patient-partnered paediatric PSC research study with PSC Partners.

Gideon Hirschfield, MB BChir, PhD, FRCP - the inaugural Lily and Terry Horner Chair in Autoimmune Liver Disease, at the University of Toronto. He is the Director of Autoimmune Liver Disease Program and the Director of Clinical Practice at Toronto Centre for Liver Disease, Francis Family Liver Clinic and specializes in Primary Biliary Cholangitis, Primary Sclerosing Cholangitis, Autoimmune Hepatitis and Transplant.

Sonya MacParland, PhD - Senior Scientist in the Ajmera Transplant Centre at UHN and an Associate Professor in the University of Toronto's department of Laboratory Medicine and Pathobiology and the department of Immunology. Dr. MacParland holds a Canada Research Chair Tier 2 in Liver Immunobiology and is the organizing Principal Investigator on a four-year patient-partnered paediatric PSC research study with PSC Partners.

Amrita Mundh, MN, NP-Peds - specializing in paediatric PSC care in the Division of Gastroenterology, Hepatology and Nutrition at the Hospital for Sick Children. She completed her Master of Nursing and Pediatric Nurse Practitioner program at the University of Toronto.

Amanda Ricciuto MD, PhD, FRCP - staff gastroenterologist in the Division of Gastrology and Hepatology & Nutrition at the Hospital for Sick Children (SickKids). Her areas of specialty included pediatric inflammatory bowel disease and IBD-associated liver disease, particularly primary sclerosing cholangitis. She is also an Assistant Professor in the Department of Pediatrics at the University of Toronto and Principal Investigator on a four-year patient-partnered paediatric PSC research study with PSC Partners.

PSC Partners Seeking a Cure Speakers:

Joanne Hatchett, RN, FNP, ACHPN - Medical Science Liaison for PSC Partners seeking a Cure

Jessica Travis - Event planner, PSC Partners Seeking a Cure

Mary Vyas, MSc, MA - President and co-founder of PSC Partners Seeking a Cure Canada, Patient Registry Strategist for PSC Partners Seeking a Cure

Register for Webinar Here https://us02web.zoom.us/webinar/register/WN_OdvgGZ5dRbCnIilwr5nppA?fbclid=IwZXh0bgNhZW0CMTAAAR0AogNwXfPddvo_Pt7JHhw_nAlbxLeeBxworREd2Cn8ds6M8SYzD_NTd5c_aem_AQBxSy5iq-AfxvHrPwOooec0x2q-Ate6PHjcFvCdeLYUaAWdr0EQH9xQIynIgBI54nhqIRpZFHGTp8Aj8daY0gs8 #/registration

05/13/2024

We are excited to share a new publication, a multicenter phase 3 clinical trial studying the effects of Maralixibat in PFIC. Maralixibat is a non-steroidal, pharmacological treatment, that inhibits the ileal bile acid transporter (IBAT). This phase 3 clinical trial found that across several PFIC types, patients on Maralixibat had improved cholestatic pruritus, markers of sleep disturbances, and predictors of native liver survival (serum bile acids and total bilirubin). These findings are not limited to BSEP deficient PFIC, but also include patients with a broad range of PFIC types and characteristics and has the potential to improve the standard of care in patients with PFIC, regardless of genotype.

Congrats to Dr. Miethke’s team here in Cincinnati, and their collaborators at 29 other hospitals!

You can access the proof for free using this share link:

Progressive familial intrahepatic cholestasis (PFIC) is a group of autosomal recessive disorders, the most prevalent being BSEP deficiency, resulting …

04/29/2024

On June 1st PSC Partners is hosting a Canadian paediatric PSC patient/family event, co-hosted with Dr. Amanda Ricciuto from the Hospital for Sick Children, and with the partnership of the Ajmera Transplant Centre and the Toronto Centre for Liver Disease of UHN. The event will be held in-person in Toronto and live-streamed for virtual attendance. Travelships to offset the expense of travel are available on a first-come, first-served basis to families living with PSC. The event will offer live French and ASL translation and free onsite childcare (for children 5-12).

REGISTRATION LINK: https://go.pscpartners.org/RegisterPaedsDay2024

The agenda will include basics of PSC, observational paediatric studies, single-cell paediatric PSC research ongoing at UHN/SickKids, mental health, and lots of Q&A time with experts. Importantly, there will be time for patients and their caregivers/families to meet with their peers and find support among the PSC community. This event is open to all paediatric PSC patients under 18 and their families.

PSC Partners Seeking a Cure Canada is a Canadian registered charity with the mission to drive research to identify treatments and a cure for primary sclerosing cholangitis (PSC), while providing education and support for those impacted by this rare disease. This Canadian registered charity was formed in 2015 and, together with US PSC Partners, shares a vision of a world where a PSC diagnosis comes with a cure.

Please reach out for more information! office@pscpartners.ca