
09/23/2024
I hope you will read my first fiction book!
As the first blood-brain barrier company, Flocel also offers an array of testing and consulting serv Flocel Inc.
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Each year pharmaceutical companies spend millions of dollars to test drugs using in vitro models of the blood-brain barrier (BBB). Flocel’s family of Dynamic In vitro Blood-Brain Barrier (DIV-BBB) products offer a unique and superior approach to this method by utilizing real human endothelial cells and the formation of tight junctions within its dynamic system, resulting in a physiologically accurate reflection of true BBB characteristics.
Version 2.0 of the DIV-BBB model boasts a highly-modular subsystem design that allows the user to assemble and modify their experimental setup in a manner most befitting their test-specific needs:
Overall, the DIV-BBB 2.0 enables more accurate pharmacokinetic and toxicological studies and reflects in vivo blood-brain barrier properties. Its replication of important endothelial cell-astrocyte interactions and ability to sustain up to four cell culture modules substantially reduces drug development cost and experimental time. In addition to BBB cell types, the cell culture modules allow for pericyte, epithelial and tumor cell growth.