03/16/2026
DENTAL ANTIBIOTIC STEWARDSHIP
Most are aware of the concept of antibiotic stewardship in medicine, which seeks to decrease the inappropriate use of antibiotics. The inappropriate use of antibiotics:
1. Exposes patients to unnecessary side effects (all medicines have side effects) and potential allergies to antibiotics. Both side effects and allergies can be life-threatening.
2. Increases bacterial resistance to antibiotics. This is why the pharmaceutical industry must constantly develop new antibiotics, because the old ones no longer work as well.
3. Increases the cost of medicine, which is shared by all through rising insurance premiums and taxes.
Last year, dentists wrote more than 27 million prescriptions for antibiotics, 80% of them were to prevent infections before or after a dental procedure, “just in case” an infection developed (https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2734798). Research has shown that antibiotic prophylaxis for tooth extractions and dental implants is frequently unnecessary (https://link.springer.com/article/10.1007/s11908-023-00802-y). 2.3 million of these antibiotic prescriptions were for clindamycin (commonly prescribed when patients report an allergy to “cillins”), second only to amoxicillin. For more than 4 decades, the clindamycin label has carried a black box warning (https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/050162s105lbl.pdf) because of its association with life-threatening Clostridium difficile-associated diarrhea (C-diff). This doesn’t mean that clindamycin should never be prescribed, but only when the potential benefits outweigh the potential harms.
This is what you, as a dental patient, can do to help with this problem:
1. Ask if antibiotics are truly needed.
2. Ask about side effects and warning signs.
3. Share your medical history with your dentist.
4. Ask about taking a shorter course.
5. Ask about delaying the antibiotic.
6. Discuss allergies. Although 10% of people report an allergy to penicillin, the true rate of penicillin allergy is less than 1% according to the CDC (https://www.cdc.gov/antibiotic-use/hcp/clinical-signs/index.html #:~:text=Key%20points,26).
https://www.cidrap.umn.edu/antimicrobial-stewardship/dentists-still-write-millions-prescriptions-year-antibiotic-life
This is part 1 in a three-part series on potential harms from taking antibiotics for dental procedures. Parts 2 and 3 will publish tomorrow and Thursday. All will be available here.