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Globalwide Health Benefit has been one of the major players in USA and around the world since 1987 We believe that your health is your most valuable asset.

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02/27/2025

Health care is an inviting target for budget cutters in Washington. One of every four dollars in federal spending in fiscal year 2024 was used to pay for health programs and services. The next-largest categories are Social Security (21%), national defense (13%) and interest payments on the national debt (13%). Combined, these four categories account for nearly three-quarters of all federal spending.

“With spending on health programs accounting for a substantial share of federal spending, those programs are an obvious target to achieve overall spending goals in current budget reconciliation discussions,” according to a new report published by KFF. “Medicaid has been the primary focus for federal spending cuts, but cuts to Medicare and the Affordable Care Act have also been floated.”

Although cuts to discretionary spending, which includes funding for several federal health agencies, veterans’ health care and global health, are not part of the reconciliation process, the administration has taken unilateral action to reduce this spending.

Related: Sickest 10% drive employer plan spending increases, researchers find

“Proposed cuts to federal spending on health programs and services have trade-offs and could increase the number of people without insurance; reduce access to health care; increase consumer costs for health care; and reduce payments for hospitals, nursing homes and other providers,” the report said “The effects would be felt by people of all incomes but would likely be concentrated among people with low incomes.”

Researchers analyzed current support from the federal government for health programs and services. The key takeaways include:

The federal government spent $1.9 trillion on health care programs and services in fiscal year 2024 (27% of all federal outlays), which collectively is the largest category of federal spending.
Forgone tax revenues to the federal government resulting from tax subsidies for employer-sponsored insurance coverage and a portion of the ACA premium tax credits together totaled $398 billion.
More than 80% of all federal support for health programs and services, including spending and tax subsidies, goes to programs that provide or subsidize health insurance coverage. This includes 36% going to Medicare, 25% to Medicaid and CHIP, 17% to employment-based health coverage and 5% to subsidies for ACA coverage.
Discretionary spending is a relatively small component of overall federal support for health programs and services. More than half (or $128 billion) of discretionary health spending paid for hospital and medical care for veterans. Discretionary health spending also provides funding for agencies such as the National Institutes of Health and the Centers for Disease Control and Prevention (CDC) (4%), as well as global health.

02/25/2025

A pancreatic cancer blood test called PAC-MANN could spot the disease early.
The disease is one of the most lethal cancers and can be hard to diagnose.

Just one drop of blood could reveal if you have pancreatic cancer.

A new test called PAC-MANN can pick up signs of the disease in people’s blood, even at an early stage, researchers report February 12 in Science Translational Medicine. The test could one day give doctors a simple way to catch the disease early, before it’s too late for treatment, says study coauthor Jared Fischer, a molecular biologist at Oregon Health and Science University in Portland.

“There’s really a desperate need in the field for an early detection test for pancreatic cancer,” he says.

Though relatively rare, pancreatic cancer is one of the most lethal cancers, responsible for more than 50,000 deaths in 2024. Patients are often diagnosed late in the cancer’s progression, because the disease can be so difficult to spot. “There are no obvious symptoms,” says biomedical engineer Jose Montoya Mira, part of the OHSU team.

Unlike what’s available for other diseases, doctors don’t have anything that can easily reveal early cases of pancreatic cancer. They’re mostly limited to biopsies and imaging tests. But pancreatic cancer does have some molecular red flags, which Montoya and Fischer tapped into with PAC-MANN. Like the ghost-gobbling hero of the classic arcade game, some pancreatic cancer proteins are known for their ability to chomp. These proteins, called proteases, break down connective tissues, giving tumors space to grow.

The team built PAC-MANN, or Protease-ACtivated MAgnetic NaNosensor, to detect one of these chomping proteins. The nanosensor is made of a magnetic bead linked to fluorescent molecules. When mixed with blood from a pancreatic cancer patient, proteases cleave the fluorescent molecules from the bead, releasing them into solution. Using a magnet, the team pulls any remaining nanosensors away. Left behind are the cleaved fluorescent bits, which glow under visible light.

The researchers tested their system on blood samples from 178 people who either didn’t have pancreatic cancer or had already been diagnosed. Ninety percent of the time, PAC-MANN correctly predicted whether patients had cancer or not. PAC-MANN correctly identified 40 out of 55 people with the disease and 120 out of 123 people without the disease, the researchers reported.

Now the team is validating its results in a larger set of people. They’re also looking into starting a clinical trial. The researchers envision their system one day being used for regular screenings in clinics, like an annual mammogram. PAC-MANN doesn’t require specialized imaging equipment or high-tech facilities to run. That means it has potential for use in underserved populations and in areas that lack the resources of big, wealthy hospitals, Montoya says.

01/29/2025

FDA Approves Drug for Hard-to-Treat Breast Cancer
Jan. 28, 2025 – The FDA has approved a new treatment for certain types of advanced breast cancer that have spread or cannot be removed with surgery.

Known as fam-trastuzumab deruxtecan but marketed under the brand name Enhertu, it is meant to treat advanced breast cancer that is HR-positive and HER2-low or ultralow, which has not improved after hormone therapy.
Breast cancer is the second most common cancer and a leading cause of cancer death among women in the United States. Each year, about 300,000 cases of breast cancer are diagnosed, with around 70% being HR-positive and HER2-negative. HER2 is a protein on the surface of breast cancer cells that promotes rapid growth and spread. While HER2-positive cancers respond well to targeted therapies, many HER2-negative tumors have low HER2 levels, and they're now recognized as HER2-low or HER2-ultralow cancers. Until recently, no targeted treatments were approved for these patients, and standard endocrine therapy followed by chemotherapy often showed limited effectiveness.
Enhertu belongs to a class of medicines called antibody-drug conjugates and is designed to target cancer cells while sparing the healthy ones. It combines a monoclonal antibody, trastuzumab, that targets HER2 with the chemotherapy drug deruxtecan. Enhertu gets selectively attached to HER2-positive cancer cells and releases the chemotherapy drug directly inside them, disrupting the cells’ DNA and stopping their growth. This allows for more precise and effective tumor targeting, even when HER2 expression is too low for other HER2-directed therapies to work. Enhertu was developed by AstraZeneca and Daiichi Sankyo and was first approved in December 2019.

The effectiveness of the drug was evaluated in a clinical trial involving 866 people with advanced HR-positive, HER2-low breast cancer whose cancer progressed after hormone or targeted therapies, without prior chemotherapy. Patients were randomly assigned to receive either Enhertu or standard chemotherapy. Results showed that Enhertu reduced the risk of cancer progression or death by 36%, compared to chemotherapy. Patients on Enhertu lived for 13.2 months on average without their cancer progressing, while those on chemotherapy lived for 8.1 months.

The most common side effects include low blood cell counts and hemoglobin and potassium levels, nausea, vomiting, constipation, diarrhea, reduced appetite, fatigue, hair loss, muscle or bone pain, and increased liver enzyme levels. In a news release, AstraZeneca explained that Enhertu can cause serious lung problems and advised patients to report any coughing, breathing issues, fever, or worsening symptoms to their doctor right away. Women of reproductive age should also tell their health care providers if they are pregnant or planning to get pregnant before starting Enhertu, as the medication can harm an unborn baby. Both men and women are also advised to talk to their doctors about using effective contraception during treatment and for four to seven months after the last dose.

01/29/2025

Breast cancer detection could get a boost from artificial intelligence.

When AI helped examine mammograms, doctors caught one more cancer case per 1,000 screened individuals compared with when they didn’t use the technology, researchers report January 7 in Nature Medicine. The largest real-world study on AI’s potential for breast cancer screening, which included nearly 500,000 women in Germany, suggests that the software could streamline the screening process without affecting the rate of false alarms.

“AI in mammography screening is at least as good as a human reader, and our study shows it’s even better,” says cancer epidemiologist Alexander Katalinic of the University of Lübeck in Germany.
Germany’s breast cancer screening program requires two radiologists to independently assess each patient’s mammograms and look for spots, abnormal masses and other peculiarities. (U.S. clinics mostly rely on one physician.) If at least one doctor suspects cancer in the four X-ray images, which are compared with the patient’s previous screening, a third radiologist helps determine if the individual needs more tests.

“We have 3 million women participating each year in this project, and 24 million pictures have to be read every year,” Katalinic says. “That’s a big workload for the radiologists.”

09/10/2024

Tips to help you build and maintain a healthy morning routine
A healthy morning routine can be an opportunity to set yourself up for a productive day.
What we choose to do in the time after we wake can help set our intentions for the day and affect our outlook for the day ahead.
A healthy morning routine can be an opportunity to set yourself up for a productive day. What we choose to do in the time after we wake can help set our intentions for the day and affect our outlook for the day ahead.

Here’s our recommended morning routine checklist with ten daily habits to help start the day feeling purposeful and inspired to get things done:

1. Wake up at the same time each day
Our circadian rhythm is like our internal clock, affecting the time we start to feel sleepy, the time we wake, and at what point we begin to feel hungry. An irregular circadian rhythm can impact the quality of our sleep and our mental health and wellbeing. Going to sleep and waking up at the same time each day (including your days off) are good daily habits that can help to regulate our circadian rhythm and make it easier to fall asleep at night and wake up in the morning.

This means avoiding hitting the ‘snooze’ button. If you find this a challenge, perhaps consider putting the alarm clock out of arms reach or using multiple alarms. Waking at the same time each day may also help you to feel more focused and less groggy.

2. Access natural light
Making sure we get exposure to daylight when we wake is another important part of maintaining a healthy circadian rhythm. Also, vitamin D, which our bodies create upon exposure to sunlight, helps our immune system1 and can improve our moods.2 Opening the curtains when you wake up at the same time each day is a good way to give the body the signals it needs.

3. Incorporate exercise into your morning routine
The benefits of regular physical activity are well known. As well as the physical benefits, exercise can help reduce stress, alleviate anxiety, boost our mood, and promote a sense of wellbeing.3 Finding time to fit physical activity into your morning routine can be a great way to feel energized and wake up your body.

4. Avoid screens first thing
It can be easy to reach for our phones as soon as we wake up, but this can be a stressful way to start the day. You may find messages or emails that you feel you need to answer or see negative news which could mean you start your day feeling anxious or upset.

Reaching for your phone can be especially hard to avoid if you are using it as your alarm clock. Try using an actual alarm clock instead of your phone, keeping your phone out of the bedroom to remove the temptation.

5. Plan your day
Spend a few minutes looking towards your day ahead and visualising what you want to happen and the things you would like to achieve. This can help put you in a positive mindset, mentally preparing you for the day ahead. Making a list of goals can help to keep you on track throughout the day, one of the benefits of having a good morning routine.

6. Start the day by drinking water
Our bodies rely on water to be able to function properly and reports show numerous health benefits to staying well hydrated, including improved mood, energy levels4 and short-term memory5. Drinking water when you wake up is a great way to kick start your metabolism and start the day as you mean to go on.

7. Set aside time for yourself
This could be setting time for meditation, reading, listening to music or something else you enjoy that might help you find the right frame of mind for your day ahead.

8. Be flexible
Allow yourself the flexibility to change your morning routine if it isn’t working for you. Remember there is no ‘one-size-fits-all’, so listen to your body and adjust your routine if necessary.

9. Keep to your routine as much as possible when travelling
When you're away from home, it can be easy to let your daily habits slip, so make an extra effort to stick to your morning routine while travelling.

10. Be Kind to yourself
Remember not to be disheartened if you go off-track with your routine, just pick it up again the next day you are able.

06/11/2024

Our Products have finally reached stores, Pharmacies, and online markets throughout the Middle east by our distributors .

05/30/2024

Anxiety: What you need to know
Stressful or traumatic events and family history could increase your risk.
Anxiety disorders are one of the most common types of mental illness.
Anxiety disorders are one of the most common types of mental illness.
Anxiety is a natural part of life, and most of us experience it at some point. You might feel nervous, jittery, or on edge before taking a test, crossing a busy street, or making an important life decision. If you experience anxiety without a reason or more often or severely than expected, it may signal an anxiety disorder.
What is anxiety?
Anxiety triggers the body’s fight or flight response: your heart beats faster, more blood flows to the muscles, your breathing becomes heavier, and your muscles tense up. These changes prepare us to respond quickly to threats. But for people with an anxiety disorder, these feelings can become overwhelming and interfere with everyday life.

Anxiety disorders are the most common form of mental illness in the United States. They can affect people of all ages, backgrounds, and walks of life. Common types include generalized anxiety disorder, social anxiety disorder, panic disorder, and specific phobias.
Who is at risk?
Anyone can develop an anxiety disorder, but some risk factors make developing one more likely. These include a family history of anxiety disorders or mental illness, experiencing traumatic or stressful events, and underlying medical conditions.
What are the symptoms?
Everyone feels anxiety differently. Some common symptoms include:
Physical symptoms such as increased heart rate, rapid breathing, dizziness, shortness of breath, and headaches
Cognitive and emotional symptoms such as irritability, difficulty concentrating, and feeling restless, worried, or unable to sit still
Changes in behavior such as avoiding places, situations, and everyday activities that trigger anxiety or taking extreme steps to reduce or eliminate what is causing the anxiety
How are anxiety disorders diagnosed?
Your health care provider will ask you questions about your symptoms and medical history. They may also do a physical examination and run tests to rule out any medical conditions that could be causing your anxiety. If necessary, they can refer you to a mental health specialist such as a psychologist, psychiatrist, or therapist.

How are anxiety disorders treated?
The good news is that anxiety is treatable. Different strategies to help manage your anxiety may involve psychotherapy, medication, or both.
Psychotherapy methods may include:
Cognitive behavioral therapy, or CBT, which teaches people different ways of thinking, behaving, and reacting to situations to help them feel less anxious or afraid
Exposure therapy, a type of CBT that helps people confront fears so they can participate in activities they have avoided
Acceptance and commitment therapy, which uses strategies such as mindfulness and goal setting to help people live fulfilling lives despite their anxiety
Medication doesn't cure anxiety, but it can help some people manage their symptoms. Some may include:

Anti-anxiety medications, which may reduce the symptoms of anxiety, panic attacks, or extreme fear and worry
Antidepressants, which can improve the way the brain uses certain chemicals that control mood or stress
Beta blockers, which can relieve physical symptoms of anxiety such as rapid heartbeat, shaking, trembling, and blushing
Other strategies can help you manage anxiety and make treatment more effective. These include exercise, relaxation techniques such as deep breathing or meditation, and lifestyle changes such as limiting caffeine and alcohol and getting enough sleep.

A strong social support system is also important, whether it's through talking to friends and family or joining a support group.

Getting help
Remember, feeling anxious sometimes is normal. But if your symptoms last a long time, get worse, or interfere with your day-to-day life, it may be a sign of an anxiety disorder. If you or someone you know is experiencing symptoms of anxiety disorders, reach out to a health care provider. Help is available, and you don't have to face your anxiety alone.

05/08/2024

The best way to help children with an anxiety disorder may be to help their parents first, a new funded study has found.

Most children worry or feel anxious from time to time. But for children with an anxiety disorder, their feelings are more constant and intense. It can cause problems at school, disrupt their sleep, and prevent them from making friends.

To help their children deal with anxiety, many parents try to accommodate them. For example, they might sleep in their bedroom to calm nighttime fears or avoid social situations that upset the child.

While this works temporarily, it doesn't teach the child how to deal with worries on their own as they get older.

supported researchers with the Yale Child Study Center decided to take a different approach. They taught parents how to respond to their child's anxieties in new ways.

The new program assigned 124 children, ages 7 to 14, who had been diagnosed with an anxiety disorder, to receive weekly cognitive behavioral therapy (CBT) sessions. The sessions helped them learn strategies to cope with their worries.

Half of the parents went through a training program at the same time. These parents learned supportive ways to respond to their child's anxiety and ways to change their own accommodating behavior.

After 12 weeks, the authors found that CBT had reduced the children's levels of anxiety. They also found that parents who were in the training program (compared to those who were not) exhibited a lower level of parenting-related stress.

Though treatment like CBT can teach children ways to cope with their worries and emotions, only about half of them respond well to it. This dual approach may help children who don't respond well to CBT.

04/01/2024

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03/31/2024

What Are Blood Clotting Disorders?

Blood clotting disorders are problems in the body’s ability to control how the blood clots. Normally, blood clots form during an injury to prevent bleeding. If you have a clotting disorder, your blood may not clot enough, which can lead to too much bleeding, or your blood may form clots even without an injury.

You can read about conditions that happen when your blood does not clot enough in our Bleeding Disorders health topic. This topic focuses on clotting disorders that happen when your blood clots more often than it should.

Blood clotting disorders are sometimes called coagulation disorders or thrombophilias. They are either inherited (meaning that you are born with the condition) or acquired (meaning you develop the condition as the result of another illness or injury). For example, antiphospholipid syndrome (APS) and disseminated intravascular coagulation (DIC) are types of acquired blood clotting disorders.

Blood clots can cause many health problems. Symptoms of blood clots depend on where in the body they form. Typically, they will form in the veins and appear in the legs or lungs. Blood clots in the legs can cause deep vein thrombosis. Blood clots in the lungs can cause a pulmonary embolism. It is rare for blood clots to form in the arteries. When they do, they can lead to heart attack or stroke.

If you think you may have a blood clotting disorder, your doctor will ask about your family and medical history. They may also run tests to be sure of the diagnosis. If you have a blood clotting disorder, you may need medicine to stop the blood from clotting. Your doctor may also talk to you about ways to prevent blood clots and to stay healthy.

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