Taking the Pulse - A Health Care Podcast

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Taking the Pulse - A Health Care Podcast

Taking the Pulse: a Health Care and Life Sciences Podcast

09/22/2025

💊 “Generic drugs account for 90% of all prescriptions in the U.S., but they are very price-sensitive, and it’d be really difficult to move manufacturing here… while also keeping drug prices down for patients.” - Gil Roth, President, Pharma & Biopharma Outsourcing Association (PBOA)

🔊 Gil joins the podcast to unpack how tariffs, executive orders, and domestic manufacturing policies are reshaping the pharmaceutical landscape. Tune in now at www.thepulsehealthcast.com!

09/16/2025

⚕️ This week on the podcast, Heather and Matthew are joined by Gil Roth, President of the Pharma & Biopharma Association (PBOA | Outsourcing-Pharma), which represents the regulatory, legislative, and general business interests of Contract Development and Manufacturing Organizations (CDMOs) in the bio/pharma space.

🔊 Gil shares how CDMOs are navigating regulatory uncertainty, the potential impact of tariffs on drug pricing and supply chains, and what recent executive orders could mean for innovation and access to care. Tune in now at www.thepulsehealthcast.com!

09/12/2025

🏥 “North Carolina sends more children out of state for care than any other state in the country when it comes to acute care specialty... We think our citizens deserve a lot better.”
— Andy Willis, Executive Chief Planning & Development Officer, NC Children's

🔊 Andy joins the podcast to share how UNC Health and Duke Health are partnering to build a new freestanding children’s hospital that will transform pediatric care across the region. Tune in now at www.thepulsehealthcast.com!

09/11/2025

⚕️Heather and Lauren are joined by Andy Willis, Executive Chief Planning and Development Officer of NC Children's, a new freestanding children’s hospital being developed through a historic partnership between UNC Health and Duke Health.

🔊 Andy shares how this $3 billion project will transform pediatric care across the state and beyond, as we dive into workforce development, economic impact, access to care, and more. Tune in now to hear how NC Children’s is poised to become one of the top pediatric hospitals in the country at www.thepulsehealthcast.com!

08/28/2025

⚕️ “Most reputable treatment centers understand that addiction is a chronic relapsing disease... They’re saying, ‘We can help you on the journey,’ not ‘We’re going to cure you.’”

🔊 Morgan Coyner and Sara Howe join the podcast to discuss how the APNC is fighting patient brokering and expanding access to addiction treatment in North Carolina. Tune in now at www.thepulsehealthcast.com!

08/21/2025

🧪“The tumor microenvironment is very harsh to immune cells. There are at least two major different types of cells that will inhibit cell therapy’s functions.”

🔊 Fangheng and Ming_Wei join the podcast to explain why solid tumors like ovarian cancer are so difficult to treat, and how RephImmune’s RACE-T technology is designed to overcome those barriers. Tune in now at www.thepulsehealthcast.com!

08/20/2025

🧬 “We are helping your own cells save your own life. It is like giving your immune system a new set of tools and a clear instruction so it can finally find and attack the cancer rather than being confused or shut down by it.”— Ming-Wei Chen, Founder & CEO of RephImmune

🔊 Ming-Wei and Fangheng join the podcast to share how RephImmune is reimagining cell therapy to fight solid tumors like ovarian cancer. Tune in now at www.thepulsehealthcast.com!

08/19/2025

🧬Ming-Wei Chen and Fangheng Zhou, the scientists behind RephImmune, join hosts Lynnsey and Matthew to discuss how their biotech startup is developing a next-generation cell therapy platform designed to overcome the limitations of CAR-T.

⚕️With a focus on ovarian cancer, RephImmune’s RACE-T technology targets solid tumors by re-engineering immune cells to better locate, pe*****te, and survive in the harsh tumor environment.

🔊 Ming and Fang share their personal motivations, the science behind their approach, and how programs like SCbio DRIVE are helping them move closer to clinical trials. Tune in now at www.thepulsehealthcast.com!

08/14/2025

🧬 “We actually believe that effective therapies for a number of the diseases, including Alzheimer’s, will be based on identifying the right patient for the therapy.”
— Pawel Krysiak, Co-Founder of Jaya Bio

🔊 Hear how Jaya Bio is using gene therapy and precision medicine to target the root causes of neurodegenerative diseases. Tune in now at www.thepulsehealthcast.com!

08/13/2025

🧬 “Our gene therapy treatment is a one and done treatment. It’s one dose and you’re done. Your gene copies are corrected and your onset of your disease is arrested.”
— Neal Goodwin, Co-Founder of Jaya Bio

🔊 Neal and Pawel share how Jaya Bio is pioneering gene therapy and precision medicine for Alzheimer’s and Parkinson’s. Tune in to episode 246 at www.thepulsehealthcast.com!

08/12/2025

🧬Lynnsey and Matthew are joined by Neal Goodwin and Pawel Krysiak of Jaya Bio, a preclinical life sciences company developing gene therapies for genetically defined neurodegenerative diseases.

🔊 They share how their team is using precision medicine to target specific mutations linked to Alzheimer’s, Parkinson’s, and frontotemporal dementia, aiming to arrest disease progression with a single dose. Our conversation explores how gene therapy works, what makes Jaya Bio’s approach different, and more. Tune in now at www.thepulsehealthcast.com!

08/07/2025

⚕️ “We don't think it should be the AI that's guiding care. We think it should be the human that's still guiding care, but making them as efficient and effective in their decision-making process as they possibly can be.” — Angela Adams, CEO of Inflo Health

🔊 Angela joins the podcast to share how Inflo Health is using AI to improve radiology follow-up and support providers. Tune in for more at www.thepulsehealthcast.com!

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