08/27/2025
Emerging research, including a significant study by British researchers*, is continually deepening our understanding of the intricate link between kidney function and heart health. As kidney health declines, the risk of heart disease can notably increase.
A key player in this connection is a molecule known as Lipoprotein(a), or Lp(a). This type of fat can contribute to arterial plaque buildup, similar to "bad" LDL cholesterol. While high Lp(a) levels are often genetic, they can also be elevated in individuals with kidney disease. Normally, healthy kidneys help regulate Lp(a) levels; impaired kidney function can lead to an increase.
Elevated Lp(a) is directly associated with a heightened risk of heart disease and stroke, especially in those with higher levels.
Currently, there are no widely available medications specifically designed to lower Lp(a). However, certain dietary modifications and supplements show promise:
🟢 Niacin: This B vitamin can reduce Lp(a) by 20-30%, but proper dosage and potential side effects (like flushing) should be discussed with your doctor.
🟢 Flaxseeds: Incorporating about 25 grams (3 tablespoons) of flaxseeds daily into your diet (e.g., in cereals or muffins) has shown to significantly lower Lp(a).
🟢 Other Natural Support: Studies suggest that L-carnitine, Coenzyme Q10, and red yeast rice may also help decrease Lp(a) levels. Always consult your doctor to ensure suitability.
Many healthcare providers do not routinely test for Lp(a). If you have concerns about your heart disease risk, particularly if you also have kidney issues, discuss Lp(a) testing with your doctor. Some walk-in labs also offer this test.
Remember, maintaining optimal kidney function is paramount for overall well-being, including robust heart health. Engage in a conversation with your doctor about your heart disease risk factors and personalized management strategies.
*Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom and the Medical Research Council Population Health Research Unit, Oxford, United Kingdom