03/11/2026
In this fluorescein angiogram, we see many classic features of Familial Exudative Vitreoretinopathy (FEVR). In the periphery, we see poor vascularization and possible dragging of the retina in the temporal direction. There is no apparent neovasculariazation in this photo. FEVR is a rare, genetically inherited condition that can mimic other retinal diseases we see more commonly in clinic, like diabetic retinopathy, retinopathy of prematurity, Coats disease, or Sickle cell retinopathy, among others. A workup should include careful examination of both eyes, history taking of family members, as well as genetic testing. Treatment can include observation for very mild cases, laser photocoagulation for evolving disease, and surgery for advanced disease with retinal detachment.
