Institute for Exercise & Environmental Medicine

We explore and define the limits to human functional capacity in health and disease, with the objective of improving the quality of life for humanity.

Two decades ago, the Institute for Exercise and Environmental Medicine (IEEM) was founded as a joint program between Texas Health Presbyterian Hospital Dallas and The University of Texas Southwestern Medical Center. Through this unique private-public partnership, IEEM researchers have made great strides, building an international reputation for innovative research efforts and clinical applications

Operating as usual

For Covid Long-Haulers, a Little-Known Diagnosis Offers Possible Treatments—and New Challenges 10/06/2021

For Covid Long-Haulers, a Little-Known Diagnosis Offers Possible Treatments—and New Challenges

"[Dr. Levine] thinks it might be premature to be diagnosing Covid patients with conditions like POTS so soon. Some athletes, for example, might instead be suffering from muscle atrophy and deconditioning caused by inactivity while convalescing from the virus. “It doesn’t mean they have POTS but they can certainly have a POTS-like physiology,” says Dr. Levine."

Learn more:
https://www.wsj.com/articles/for-covid-long-haulers-a-little-known-diagnosis-offers-possible-treatmentsand-new-challenges-11606761541

For Covid Long-Haulers, a Little-Known Diagnosis Offers Possible Treatments—and New Challenges A disorder called POTS offers some treatment paths, but they are often arduous.

Exercise boosts blood flow to the brain, study finds 10/05/2021

Exercise boosts blood flow to the brain, study finds

https://www.utsouthwestern.edu/newsroom/articles/year-2021/exercise-boosts-blood-flow-to-the-brain.html

Exercise boosts blood flow to the brain, study finds It’s not just your legs and heart that get a workout when you walk briskly; exercise affects your brain as well.

10/05/2021

The Syncope & Autonomic Dysfunction Clinic at the IEEM provides expert outpatient care for those experiencing dysautonomia.

Learn more: https://www.texashealth.org/ieem/Patient-Care/Syncope-and-Autonomic-Dysfunction-Clinic

The Syncope & Autonomic Dysfunction Clinic at the IEEM provides expert outpatient care for those experiencing dysautonomia.

Learn more: https://www.texashealth.org/ieem/Patient-Care/Syncope-and-Autonomic-Dysfunction-Clinic

Sports Cardiologist Explores the Outer Limits - American College of Cardiology 10/04/2021

Sports Cardiologist Explores the Outer Limits - American College of Cardiology

“As a physician, what interests me most is what we can learn from these extraordinary individuals about patients and their endurance. Indeed, what limits a climber on the summit of Mt. Everest is remarkably similar to what limits patients with heart disease (such as heart failure) from being able to accomplish their activities of daily living." Dr. Benjamin Levine, M.D., Director, IEEM

Learn more: https://www.acc.org/latest-in-cardiology/articles/2016/08/22/09/23/sports-cardiologist-explores-the-outer-limits

Sports Cardiologist Explores the Outer Limits - American College of Cardiology Sports Cardiologist Explores the Outer Limits Aug 25, 2016 Cardiology Magazine Share via: Font Size A A A The images on the screen at NASA’s Johnson Space Center began as sounds, transmitted via sonar from an echocardiogram machine measuring the heartbeat of Ben Lecomte, who is currently swimming ...

These Benefits of Hiking Will Make You Want to Hit the Trails 10/03/2021

These Benefits of Hiking Will Make You Want to Hit the Trails

"Grab your backpack for a day hike, and you can expect to burn some 520 calories per hour (based on a 140-pound woman) — about the same as if you were running a 5 mph pace. But this benefit of hiking won’t seem that sweaty. “Exercising outdoors has been found to be easier in that you feel less fatigue or pain and can go faster and longer than if you were indoors.” Learn more:

https://www.shape.com/fitness/cardio/benefits-hiking-will-make-you-want-hit-trails

These Benefits of Hiking Will Make You Want to Hit the Trails Even a leisurely stroll on a nature trail can do your mental and physical health some good.

Rhabdomyolysis: Pathogenesis, Diagnosis, and Treatment 10/02/2021

Rhabdomyolysis: Pathogenesis, Diagnosis, and Treatment

The primary focus of the Neuromuscular Disease Center Clinic at the IEEM are diseases of muscle metabolism, such as rhabdomyolysis.

Learn more: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365849/

Rhabdomyolysis: Pathogenesis, Diagnosis, and Treatment Rhabdomyolysis is a complex medical condition involving the rapid dissolution of damaged or injured skeletal muscle.This review focuses on the epidemiology, pathophysiology, causes, presentation, diagnosis, complications, management, and anesthetic considerations ...

Mitochondrial Myopathy Fact Sheet | National Institute of Neurological Disorders and Stroke 10/02/2021

Mitochondrial Myopathy Fact Sheet | National Institute of Neurological Disorders and Stroke

The primary focus of the Neuromuscular Disease Center Clinic at the IEEM are diseases of muscle metabolism, such as mitochondrial myopathies.

Learn more: https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Mitochondrial-Myopathy-Fact-Sheet

Mitochondrial Myopathy Fact Sheet | National Institute of Neurological Disorders and Stroke What are mitochondrial myopathies? What causes mitochondrial myopathies? What are the symptoms of mitochondrial myopathy? Special issues in mitochondrial disease What issues are of special concern in children? Are there specific treatments for the mitochondrial myopathies?

VLCAD deficiency | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program 10/01/2021

VLCAD deficiency | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program

The primary focus of the Neuromuscular Disease Center Clinic at the IEEM are diseases of muscle metabolism, such as very long-chain acyl-CoA dehydrogenase deficiency (VLCADD).

Learn more: https://rarediseases.info.nih.gov/diseases/5508/vlcad-deficiency

VLCAD deficiency | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for VLCAD deficiency

Primary carnitine deficiency | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program 10/01/2021

Primary carnitine deficiency | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program

The primary focus of the Neuromuscular Disease Center Clinic at the IEEM are diseases of muscle metabolism, such as primary carnitine deficiency.

Learn more: https://rarediseases.info.nih.gov/diseases/5104/primary-carnitine-deficiency

Primary carnitine deficiency | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Primary carnitine deficiency

Carnitine palmitoyltransferase 2 deficiency | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program 09/30/2021

Carnitine palmitoyltransferase 2 deficiency | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program

The primary focus of the Neuromuscular Disease Center Clinic at the IEEM are diseases of muscle metabolism, such as Carnitine palmitoyltransferase II (CPT II).

Learn more: https://rarediseases.info.nih.gov/diseases/1121/carnitine-palmitoyltransferase-2-deficiency

Carnitine palmitoyltransferase 2 deficiency | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Carnitine palmitoyltransferase 2 deficiency

Glycogen storage disease type 2 | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program 09/30/2021

Glycogen storage disease type 2 | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program

The primary focus of the Neuromuscular Disease Center Clinic at the IEEM are diseases of muscle metabolism, such as Pompe disease (GSD2).

Learn more: https://rarediseases.info.nih.gov/diseases/5714/glycogen-storage-disease-type-2

Glycogen storage disease type 2 | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Glycogen storage disease type 2

Glycogen storage disease type 7 | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program 09/29/2021

Glycogen storage disease type 7 | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program

The primary focus of the Neuromuscular Disease Center Clinic at the IEEM are diseases of muscle metabolism, such as Tarui disease (GSD7).

Learn more: https://rarediseases.info.nih.gov/diseases/5686/glycogen-storage-disease-type-7

Glycogen storage disease type 7 | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Glycogen storage disease type 7

Glycogen storage disease type 5 | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program 09/29/2021

Glycogen storage disease type 5 | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program

The primary focus of the Neuromuscular Disease Center Clinic at the IEEM are diseases of muscle metabolism, such as McArdle's disease (GSD5).

Learn more: https://rarediseases.info.nih.gov/diseases/6528/myophosphorylase-deficiency

Glycogen storage disease type 5 | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Glycogen storage disease type 5

09/28/2021

Meet the IEEM faculty!

Dr. Alan W. Martin, M.D., Clinical Director, Neuromuscular Disease Center Clinic, IEEM

Learn more: https://texasneurology.com/providers/martin/index.asp

Meet the IEEM faculty!

Dr. Alan W. Martin, M.D., Clinical Director, Neuromuscular Disease Center Clinic, IEEM

Learn more: https://texasneurology.com/providers/martin/index.asp

09/28/2021

Meet the IEEM faculty!

Dr. Salman Bhai, M.D.

Assistant Professor, Neurology and Neurotherapeutics, UTSW
Principal Investigator, Neuromuscular Disease Center, IEEM

Dr. Bhai specializes in the evaluation, diagnosis, and treatment of neuromuscular disorders. He specifically focuses on patients with inflammatory and metabolic myopathies as well as those with immune checkpoint inhibitor complications.

Learn more: https://www.texashealth.org/ieem/Faculty/Salman-Bhai

Meet the IEEM faculty!

Dr. Salman Bhai, M.D.

Assistant Professor, Neurology and Neurotherapeutics, UTSW
Principal Investigator, Neuromuscular Disease Center, IEEM

Dr. Bhai specializes in the evaluation, diagnosis, and treatment of neuromuscular disorders. He specifically focuses on patients with inflammatory and metabolic myopathies as well as those with immune checkpoint inhibitor complications.

Learn more: https://www.texashealth.org/ieem/Faculty/Salman-Bhai

Aerobic Exercise May Improve Cognitive Function 09/27/2021

Aerobic Exercise May Improve Cognitive Function

“Aerobic exercise is very important for improving both vascular function and brain function,” said Rong Zhang, PhD, a professor of neurology at the University of Texas Southwestern Medical Center." Learn more:

https://www.healthline.com/health-news/can-aerobic-exercise-improve-cognitive-function-and-decrease-alzheimers-disease-risk

Aerobic Exercise May Improve Cognitive Function Moderate to vigorous-intensity aerobic exercise may benefit adults with mild cognitive impairment, according to a new study by researchers at the University of Texas Southwestern Medical Center. Finding ways to help people with mild cognition is important to potentially combat rising cases of Alzhei...

A year of committed exercise in middle age reversed worrisome heart stiffness 09/27/2021

A year of committed exercise in middle age reversed worrisome heart stiffness

" "It is considered by some to be one of the most important virtually untreatable diseases in cardiovascular medicine," said Dr. Benjamin Levine, the study's senior author. "So, of course, if there are no therapies, then the most important thing to do is to figure out how to prevent it from happening in the first place." "

https://www.heart.org/en/news/2021/09/20/a-year-of-committed-exercise-in-middle-age-reversed-worrisome-heart-stiffness

A year of committed exercise in middle age reversed worrisome heart stiffness A year of exercise training preserved or increased youthful elasticity of the heart muscle among middle-aged people with early signs of heart failure, new research shows.

Exercise Is a Powerful Tool to Help Fight Dementia. But Which Type Is Best? 09/27/2021

Exercise Is a Powerful Tool to Help Fight Dementia. But Which Type Is Best?

"Tsubasa Tomoto of the Department of Neurology at the University of Texas Southwestern Medical Center in Dallas, led the research on this year-long study, which focused on the vascular function of the brain before and after the exercise intervention. '"We showed that the aerobic training improved cerebral vascular motor reactivity (CVMR), whereas stretching (the control in this study) had no effect. That improved CVMR also correlated to improvement on more memory scores," said Tomoto.""

Learn more: https://www.nextavenue.org/exercise-alzheimers-prevention/

Exercise Is a Powerful Tool to Help Fight Dementia. But Which Type Is Best? Yoga, pilates, HIIT and weight lifting are all good, but some are better at slowing cognitive decline

Is Dancing an Exercise? 09/26/2021

Is Dancing an Exercise?

"Dancing is aerobic exercise that requires the use of energy and coordination. [It] reduces stress levels, increases heart rate, and helps with endurance. Dancing also increases muscle strength, especially those in the legs." Learn more:

https://www.palomagazine.com/2020/10/01/is-dancing-an-exercise/

Is Dancing an Exercise? If you like to dance, I have great news for you, dancing can help you burn calories and make you lose those extra pounds.

09/25/2021

The Hyperbaric Medicine Center at the IEEM is accredited as a "Level One - With Distinction" clinical hyperbaric facility by the Undersea & Hyperbaric Medical Society (UHMS). The UHMS hyperbaric facility accreditation program is the only hyperbaric-specific accreditation to be recognized by The Joint Commission as a Complementary Accrediting organization under the TJC’s Cooperative Agreement Initiative. Learn more about the Hyperbaric Medicine Center at the IEEM: https://www.texashealth.org/ieem/Patient-Care/Hyperbaric-Medicine-Center

The Hyperbaric Medicine Center at the IEEM is accredited as a "Level One - With Distinction" clinical hyperbaric facility by the Undersea & Hyperbaric Medical Society (UHMS). The UHMS hyperbaric facility accreditation program is the only hyperbaric-specific accreditation to be recognized by The Joint Commission as a Complementary Accrediting organization under the TJC’s Cooperative Agreement Initiative. Learn more about the Hyperbaric Medicine Center at the IEEM: https://www.texashealth.org/ieem/Patient-Care/Hyperbaric-Medicine-Center

09/24/2021

The Hyperbaric Medicine Center at the IEEM treats approved hyperbaric indications as recognized by the Undersea & Hyperbaric Medical Society (UHMS). In-vitro and in-vivo pre-clinical research data, as well as extensive positive clinical experience and study, are required for indications to achieve UHMS approval.

Learn more about UHMS-approved hyperbaric indications: https://www.texashealth.org/ieem/Patient-Care/Hyperbaric-Medicine-Center/Approved-Conditions

The Hyperbaric Medicine Center at the IEEM treats approved hyperbaric indications as recognized by the Undersea & Hyperbaric Medical Society (UHMS). In-vitro and in-vivo pre-clinical research data, as well as extensive positive clinical experience and study, are required for indications to achieve UHMS approval.

Learn more about UHMS-approved hyperbaric indications: https://www.texashealth.org/ieem/Patient-Care/Hyperbaric-Medicine-Center/Approved-Conditions

09/23/2021

"A phase 2B randomised trial of hyperbaric oxygen therapy for ulcerative colitis patients hospitalised for moderate to severe flares"

Parambir S. Dulai, Laura E. Raffals, David Hudesman, Michael Chiorean, Raymond Cross, Tasneem Ahmed, Michael Winter, Shannon Chang, David Fudman, Charlotte Sadler, Ernest L. Chiu, Frank L. Ross, Gary Toups, M. Hassan Murad, Kinjal Sethuraman, James R. Holm, Renie Guilliod, Benjamin Levine, Jay C. Buckey Jr, Corey A. Siegel

03 August 2020 https://doi.org/10.1111/apt.15984C

"A phase 2B randomised trial of hyperbaric oxygen therapy for ulcerative colitis patients hospitalised for moderate to severe flares"

Parambir S. Dulai, Laura E. Raffals, David Hudesman, Michael Chiorean, Raymond Cross, Tasneem Ahmed, Michael Winter, Shannon Chang, David Fudman, Charlotte Sadler, Ernest L. Chiu, Frank L. Ross, Gary Toups, M. Hassan Murad, Kinjal Sethuraman, James R. Holm, Renie Guilliod, Benjamin Levine, Jay C. Buckey Jr, Corey A. Siegel

03 August 2020 https://doi.org/10.1111/apt.15984C

09/22/2021

The Hyperbaric Medicine Center at the IEEM offers a full scope of services for the hyperbaric patient, including: emergent treatment of life or limb-threatening conditions, advanced critical care, and exceptional pediatric care. Learn more:

https://www.texashealth.org/ieem/Patient-Care/Hyperbaric-Medicine-Center

The Hyperbaric Medicine Center at the IEEM offers a full scope of services for the hyperbaric patient, including: emergent treatment of life or limb-threatening conditions, advanced critical care, and exceptional pediatric care. Learn more:

https://www.texashealth.org/ieem/Patient-Care/Hyperbaric-Medicine-Center

National Postdoc Appreciation Week – Excellence in Postdoc Mentoring Award Seminar 09/21/2021

National Postdoc Appreciation Week – Excellence in Postdoc Mentoring Award Seminar

"This week is national postdoc appreciation week, so please take a moment to acknowledge our incredibly hard working postdocs who come from all over the world to work with us at the IEEM. They provide the energy and new ideas that keep us at the cutting edge of human physiology, as well as the rich texture of the IEEM training environment. I want to also call attention to one of the highlighted talks by our own Craig Crandall who is the recipient of the Award for Excellence in Postdoctoral Mentoring this year, and who will be giving a special lecture on Wednesday at 12:30 on “Mentoring 101: Suggestions for Postdoctoral Fellows and New Faculty." - Dr. Benjamin Levine, M.D. - Director, IEEM

Learn more: https://events.utsouthwestern.edu/event/national_postdoc_appreciation_week_excellence_in_postdoc_mentoring_award_seminar#.YUi3SHOSlaR

National Postdoc Appreciation Week – Excellence in Postdoc Mentoring Award Seminar Speaker: Craig Crandall, Ph.D., Professor of Internal Medicine , UT Southwestern Director of the Thermal and Vascular Physiology at the Institute for Exercise and Environmental Medicine (IEEM). Title: “Mentoring 101: Suggestions for Postdoctoral Fellows and New Faculty"

Our Story

The Institute for Exercise and Environmental Medicine (IEEM) explores and defines the limits to human functional capacity in health and disease, with the objective of improving the quality of life for human beings of all ages.

The IEEM focus of “every patient as an individual” uses the science of integrative physiology as “truly personalized medicine.” Our approach emphasizes the complexity of the respective parts of the human body and how the myriad parts are interwoven to create a functional whole. The combination of scientific study and practical medicine enables the IEEM to “put things together” - effectively bridging academic research with modern clinical methodology.

The IEEM faculty, physicians, staff, and students pursue our objectives through an integrated series of world class research laboratories and innovative patient care clinics. Every IEEM entity, each defining a specific research and clinical focus, provides collaborative expertise concerning relevant aspects of human physiology and medicine.

Videos (show all)

The Cerebrovascular Laboratory at the IEEM hosted the Risk Reduction for Alzheimer's Disease Holiday Party, Wednesday, D...
The Institute for Exercise and Environmental Medicine
Our patients are loving the new style! The IEEM first floor reception area.http://www.ieemphd.org/cardiovascular-physiol...
Pregnancy Research Study - IRB# STU 012011-198
Dr. Renie Guilliod, MD: A Personal Journey

Location

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7232 Greenville Avenue
Dallas, TX
75231

Opening Hours

Monday 7:30am - 4:30pm
Tuesday 7:30am - 5pm
Wednesday 7:30am - 5pm
Thursday 7:30am - 5pm
Friday 7:30am - 5pm
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