12/22/2025
New findings from the ALBERT trial on immunotherapy for alveolar soft part sarcoma (ASPS)
Researchers at the National Cancer Center Hospital in Japan investigated atezolizumab (an immunotherapy drug) in 20 patients with alveolar soft part sarcoma (ASPS), a rare type of soft tissue cancer.
What they found:
- 2 patients had their tumors completely disappear for over a year.
- 80% of patients saw their disease controlled.
- Patients who responded had more active immune cells (CD8+ T cells) in their tumors before starting treatment.
These immune cells may help doctors predict who will benefit from this treatment.
This study adds important evidence for using immunotherapy in rare cancers and may help identify which patients are most likely to respond. Read the full study: https://www.ejcancer.com/article/S0959-8049(25)00990-6/fulltext