11/18/2025
Vasomotor Symptoms and use of Estrogen. Vasomotor symptoms (hot flashes and night sweats) last on average 7-10 years and over 70% of women experience them. They can significantly affect a women’s quality of life and cause sleep disturbances which can lead to depression, fatigue, irritability, and anxiety. Though the physiology is not fully understood, the gradual decline or fluctuation of estradiol has been shown to be the causative factor. Due to this strong association, HRT has been demonstrated to be the most effective treatment against those hot flashes that are moderate to severe.
