Duke Clinical Research

08/25/2025

A groundbreaking clinical trial is taking a new approach to treat seizures: brain cell transplantation.Duke is one of the first sites in the U.S. to treat a ...

08/20/2025

The "munchies" have long been an amusing side effect of cannabis use. However, Duke researchers are uncovering evidence that these episodes might upend people's natural appetite cycles and be a signal of deeper problems.

Read more --> https://medschool.duke.edu/stories/rewiring-cannabis-addicted-brain

07/24/2025

Duke researchers are investigating what might prove to be a direct link between the microbiome (the "gut") and the brain that may shape people's behaviors and specific appetites.

Learn more --> https://medschool.duke.edu/stories/newly-discovered-sixth-sense-links-gut-microbes-brain-real-time

07/09/2025

𝙒𝙝𝙖𝙩 𝙞𝙨 𝙩𝙝𝙚 𝙏𝙐𝙇𝙄𝙋 𝙨𝙩𝙪𝙙𝙮 𝙖𝙗𝙤𝙪𝙩?
We are inviting you to participate in this approximately 11-month research study if you recently delivered a baby and are now experiencing bladder leakage, which is a very common problem that can be burdensome for new mothers. This research study is being conducted to compare three different treatment strategies for improving urinary leakage using your pelvic muscles, which support your bladder:

• 𝗣𝗮𝘁𝗶𝗲𝗻𝘁 𝗘𝗱𝘂𝗰𝗮𝘁𝗶𝗼𝗻: Detailed information and instructions about lifestyle changes and pelvic muscles exercises that may improve accidental bladder leakage

• 𝗣𝗲𝗹𝘃𝗶𝗰 𝗙𝗹𝗼𝗼𝗿 𝗠𝘂𝘀𝗰𝗹𝗲 𝗧𝗵𝗲𝗿𝗮𝗽𝘆 (𝗣𝗙𝗠𝗧): Coaching sessions with a skilled provider to learn and practice pelvic muscle exercises

• 𝗣𝗲𝗹𝘃𝗶𝗰 𝗠𝘂𝘀𝗰𝗹𝗲 𝗘𝘅𝗲𝗿𝗰𝗶𝘀𝗲𝘀 𝘄𝗶𝘁𝗵 𝗟𝗲𝘃𝗮®: Exercises guided by an at-home motion-based vaginal insert device (Leva®) that connects wirelessly with a smartphone app to inform the user when correct exercises are being performed

𝙔𝙤𝙪 𝙢𝙖𝙮 𝙗𝙚 𝙚𝙡𝙞𝙜𝙞𝙗𝙡𝙚 𝙩𝙤 𝙥𝙖𝙧𝙩𝙞𝙘𝙞𝙥𝙖𝙩𝙚 𝙞𝙛:
• You are 18 years of age or older, and have delivered your first baby (without the need for a cesarean) in the last 4 to 12 weeks.
𝗔𝗡𝗗
• Your baby was large at birth (7.7 pounds or more), and/or your delivery was assisted with the use of forceps or vacuum, and/or you experienced a 2nd, 3rd, or 4th-degree tear during delivery. (These factors mean that you are at an increased risk of ongoing pelvic floor disorders)

𝙋𝙖𝙧𝙩𝙞𝙘𝙞𝙥𝙖𝙣𝙩𝙨 𝙢𝙖𝙮 𝙗𝙚 𝙘𝙤𝙢𝙥𝙚𝙣𝙨𝙖𝙩𝙚𝙙:
Eligible participants who complete study-related procedures such as pelvic exams may receive up to $500 in compensation and may receive an additional $90 if optional biological samples are also provided.

𝗜𝗳 𝘆𝗼𝘂 𝘄𝗼𝘂𝗹𝗱 𝗹𝗶𝗸𝗲 𝗺𝗼𝗿𝗲 𝗶𝗻𝗳𝗼𝗿𝗺𝗮𝘁𝗶𝗼𝗻 𝗮𝗯𝗼𝘂𝘁 𝘁𝗵𝗲 𝗧𝗨𝗟𝗜𝗣 𝘀𝘁𝘂𝗱𝘆, 𝗽𝗹𝗲𝗮𝘀𝗲 𝗮𝘀𝗸 𝘆𝗼𝘂𝗿 𝗽𝗿𝗼𝘃𝗶𝗱𝗲𝗿 𝗼𝗿 𝗰𝗼𝗻𝘁𝗮𝗰𝘁 𝗼𝘂𝗿 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗰𝗼𝗼𝗿𝗱𝗶𝗻𝗮𝘁𝗼𝗿𝘀:

𝗦𝘁𝗲𝗽𝗵𝗮𝗻𝗶𝗲 𝗬𝘂
𝟵𝟭𝟵-𝟰𝟬𝟭-𝟭𝟬𝟭𝟲
𝘀𝗸𝘆𝟭𝟲@𝗱𝘂𝗸𝗲.𝗲𝗱𝘂

Learn more --> https://bit.ly/TULIP-study

Pro00115138

06/18/2025

𝗗𝗼𝗲𝘀 𝘆𝗼𝘂𝗿 𝗰𝗵𝗶𝗹𝗱 𝗵𝗮𝘃𝗲 𝗮𝗯𝗱𝗼𝗺𝗶𝗻𝗮𝗹 𝗽𝗮𝗶𝗻?
𝗜𝗳 𝘀𝗼, 𝘁𝗵𝗲𝘆 𝗺𝗮𝘆 𝗯𝗲 𝗲𝗹𝗶𝗴𝗶𝗯𝗹𝗲 𝗳𝗼𝗿 𝘁𝗵𝗲 𝗣𝘀𝘆𝗹𝗹𝗶𝘂𝗺 𝗦𝘁𝘂𝗱𝘆…

Children between the ages of 12 and 17 years are needed to participate in a research study.

To be eligible for the study, children must at least:
1) Have irritable bowel syndrome (chronic abdominal pain)
2) Be between 12-17 years of age

Children cannot be the in the study if they have had/have:
1) Previous bowel surgery
2) Documented GI disorders (e.g., ulcerative colitis)
3) Serious chronic medical conditions (e.g., diabetes)
4) Chronic conditions with GI symptoms (e.g., vasculitis, cystic fibrosis, renal disease)
5) Been on antibiotics or probiotics within the past 3 months
6) Currently pregnant
7) Autism spectrum disorder, significant developmental delay, psychosis, major depression, or a history of bipolar disorder.
8) Been taking the following medications: carbamazepine, diabetes medications, cholesterol-lowering medications, digoxin, and lithium.

You will be compensated for your time.

For more information, please contact Annette Babu at Duke Department of Pediatrics.
Email: annette.babu@duke.edu
Phone: 919-660-1227

PRO00114630

06/12/2025

Duke scientist and researcher, Dr. Nanthia Suthana, PhD, is on a quest to tap the full potential of deep brain stimulation. Her lab at Duke is exploring the relationship between emerging wireless technology, implants, and the complex neurological processes that drive memory and emotion. Her research into deep brain electrostimulation is hoping to open new pathways into the treatment of neurological diseases like Alzheimer's or PTSD.

Read more --> https://medschool.duke.edu/stories/learning-language-brain

Check out Dr. Suthana's work --> https://suthanalab.com/

05/28/2025

𝗗𝗼 𝗬𝗼𝘂 𝗛𝗮𝘃𝗲 𝗣𝗿𝗲𝗱𝗶𝗮𝗯𝗲𝘁𝗲𝘀? 𝗔𝗿𝗲 𝗬𝗼𝘂 𝗔𝗴𝗲 𝟲𝟬 𝗼𝗿 𝗢𝗹𝗱𝗲𝗿? 𝗪𝗮𝗻𝘁 𝘁𝗼 𝗜𝗻𝗰𝗿𝗲𝗮𝘀𝗲 𝗬𝗼𝘂𝗿 𝗦𝘁𝗿𝗲𝗻𝗴𝘁𝗵?

Join the Duke Vivo Prediabetes research study! Individuals must be 60 years or older, have a history of prediabetes, and are not taking medications for diabetes or weight loss. The study is online and will last 15 weeks, with four in-person visits.

𝙁𝙤𝙧 𝙢𝙤𝙧𝙚 𝙞𝙣𝙛𝙤𝙧𝙢𝙖𝙩𝙞𝙤𝙣:
Call: 919-681-9000
Email: VivoPrediabetes@Duke.edu

Pro00110021

05/27/2025

Researchers with the Duke Center for Brain and Spine Metastasis are partnering with graduate students in the Duke Department of Radiology to find out how artificial intelligence (AI) can improve clinicians' ability to make a critical decision for treating patients who have cancer that has spread to the brain.

Current medical technology remains limited in how much it can help doctors figure out if changes to patients' brain images after radiation represent recurrence (a return of the cancer) or radionecrosis (a possible side effect of radiation therapy that can can cause tissue death). Making this distinction is critical to ensure that patients receive the best treatment option.

The team of researchers here is proposing to use a "deep learning" approach that leverages AI to help doctors distinguish between radionecrosis and recurrence for their patients. Team members say deep learning can automatically learn complex patterns from imaging and patient data, which can make it a powerful tool for capturing differences between radionecrosis and tumor recurrence.

Read More --> https://www.dukecancerinstitute.org/blogs/new-ai-methods-advance-diagnosis-after-brain-metastasis-treatment

04/25/2025

04/14/2025

We do research not only because it benefits the current generations of people whom we serve, but because it can also enable the health and existence of the generations to come.

Sabrina Lewandowski woke up one morning 23 years ago with a headache that should have killed her. The cause was a stage four glioblastoma multiforme – a part...

04/07/2025

It's never too early to find your passion to pursue a career in the health sciences! We're very proud to work in partnership with local community organizations under the Duke Health Professions Recruitment and Exposure Program (HPREP) to foster a life-long interest in science for the next generation of health care workers and researchers.

Read More --> https://ctsi.duke.edu/news/duke-community-partnership-spurs-students-interest-science-health

Learn more about HPREP --> https://sites.duke.edu/centerforpathwayprograms/hprep-health-profession-recruitment-and-exposure-program/

03/20/2025

❤️Thank you to our Project Baseline participants in Kannapolis and Durham for making this research possible!

⌚️Resting heart rate measured with the investigational watch that participants wore during Project Baseline Health Study correlates strongly with ECG, considered the gold standard.

🤝 managed Duke's Project Baseline site, led by Svati H. Shah, MD. The project was a collaboration with Duke, Stanford, Verily Life Sciences, and others.

🎉We enrolled 1,000 Duke participants in the Project Baseline Health Study. Thank you !

🖊️ duke.is/c/dux9

Duke Clinical Research | DCRI