Society for Translational Oncology

12/05/2025

A new international study highlighted in STAT points to a major breakthrough in cervical cancer prevention: a single dose of the HPV vaccine may provide protection comparable to the traditional two-dose schedule.

This has significant implications for global health. A one-dose strategy could make vaccination more accessible, reduce costs, and help reach individuals in communities where completing multi-dose series is challenging.

Cervical cancer remains one of the most preventable cancers and expanding HPV vaccination is a critical step toward closing the equity gap worldwide.

Read more: https://www.statnews.com/2025/12/04/hpv-vaccine-single-shot-cervical-cancer-prevention/

A single HPV vaccination appears just as effective as two doses at preventing the viral infection that causes cervical cancer, researchers reported in a new study.

10/27/2025

ChatGPT demonstrates efficiency in clinical trial recruitment https://buff.ly/cMlROFK

AI-assisted trial recruitment: promising, but not perfect.

A new study in Machine Learning: Health evaluated how ChatGPT (GPT-3.5 and GPT-4) performs in identifying eligible patients for a head and neck cancer trial.

🔹 GPT-4 outperformed GPT-3.5 (AUC 0.838 vs 0.761) in identifying eligible patients
🔹 Structured prompts + expert guidance improved accuracy
🔹 GPT-4 was slower and costlier (7.9–12.4 min, ~$0.15–$0.27 per screen), but still efficient at scale
🔹 Best use case: AI to narrow candidates → clinician to confirm eligibility

Dr. Michael Dohopolski (UT Southwestern) noted that while LLMs can’t yet interpret nuanced clinical criteria, they can dramatically reduce manual workload in screening electronic health records.

As AI evolves, these tools could become valuable adjuncts for research teams facing limited personnel and time pressures, provided models remain HIPAA-compliant and clinician oversight stays central.

Multiple versions of ChatGPT demonstrated efficacy in identifying eligible patients for clinical trial recruitment, showing potential to complement manual chart reviews, according to a study published in Machine Learning: Health.Improving clinical trial recruitment has been an ongoing challenge in t...

10/27/2025

Explore 10 significant events in the history of breast cancer. Discover more here: https://buff.ly/E4AC4xz

Our understanding of breast cancer has evolved significantly since it was first documented nearly 5,000 years ago. Explore some of the many milestones in the history of breast cancer research and treatment.

06/23/2025

A recent study shows that telehealth interventions tailored for older adults with cancer can significantly improve clinical outcomes including lower treatment toxicity and improved survival.
This reinforces the value of geriatric assessments and personalized care even when delivered virtually.

📖 Read more: https://www.healio.com/news/hematology-oncology/20250612/telehealth-program-significantly-improves-outcomes-for-older-adults-with-cancer

A telehealth-based intervention program helped older adults with metastatic cancer improve their physical function, mood and quality of life compared with standard care, according to results of a randomized trial.The investigation, conducted with patients from Brazil, showed Geriatric Assessment-Gui...

06/05/2025

Symptom-assessment intervention may improve care, reduce costs for older adults with cancer

A study presented at the ASCO 2025 Annual Meeting demonstrates that a proactive symptom assessment intervention, involving weekly check-ins by trained lay health workers, significantly reduces acute care utilization among older adults with cancer. Patients receiving this intervention experienced fewer emergency department visits and hospitalizations, leading to an average cost saving of $12,000 per patient. This approach underscores the value of integrating low-cost, scalable interventions to enhance care quality and reduce expenditures in geriatric oncology.

CHICAGO — A weekly symptom-assessment intervention led by trained lay health workers may help reduce acute care use and improve end-of-life care for older adults with cancer, according to data presented at ASCO Annual Meeting.Such an approach could help these patients avoid frequent and costly...

04/30/2025

“Taking care and offering somebody a clinical trial takes more time, more effort—and that’s not necessarily reflected in clinical productivity.”

At this year’s meeting, the PAACT study shared eye-opening interviews with healthcare professionals about why many Black/African American patients still don’t have access to cancer clinical trials.

From mistrust and implicit bias to time burdens and lack of support—there’s a lot to fix. But PAACT has a roadmap. And PAACT 2.0 is already putting it to the test.

Let’s support inclusive, patient-centered research.

Home to the journal Oncology, Cancer Network provides research and opinion on the screening, early detection, diagnosis, treatment, and prevention of cancers.

02/01/2025

Understanding Motives Behind Participation in Cancer Clinical Trials https://buff.ly/4aJRkHc

Exploring the motivations for participating in cancer clinical trials reveals a complex interplay of factors. Participants often join these studies driven by the hope of accessing cutting-edge treatments or contributing to scientific advancements that may benefit future patients. Understanding these motives can improve recruitment strategies and enhance the overall success of clinical trials.

Recent survey study of 978 cancer patients and their relatives uncovered reasons behind their willingness, or lack thereof, to participate in clinical research.

01/31/2025

Baseline Geriatric Assessment and QOL Impact Chemotherapy Survival in Pancreatic Cancer https://buff.ly/3Q0bPWg

01/31/2025

Cervical cancer is preventable, sexually transmitted, and highly curable—even in late stages. This interview, Prof. Bello Abubakar shares key insights on prevention, education, and emerging technologies like liquid biopsy. https://buff.ly/3E8sHaN

01/31/2025

Key Strategies to Promote Professional Wellness and Reduce Burnout in Oncology Clinicians | JCO Oncology Practice https://buff.ly/40DAuoB

01/30/2025

How to Foster a People-Centered Environment in Cancer Treatment https://buff.ly/42yCUaE

01/30/2025

Understanding the Cervical Cancer Crisis: Insights from Professor Lola Adeyemi

Cervical cancer is the second most common cancer among women worldwide, yet it remains one of the most preventable. So why does it continue to claim so many lives? The answer lies in gaps in awareness, education, and access to screening—barriers that disproportionately affect underserved communities.

In a thought-provoking discussion with Professor Lola Adeyemi, a physician, entrepreneur, and advocate for health equity, she shared key strategies for closing these gaps and advancing cervical cancer prevention. As the Co-founder and COO of Magna Carta Health, she is leveraging technology-driven solutions to transform preventative healthcare in Nigeria.

Key Takeaways from the Conversation:
- Awareness is everything—many people either don’t know, don’t understand, or don’t prioritize cervical cancer prevention.
- Access to screening remains a major challenge, and self-testing kits offer a promising solution to expand reach.
- Technology can transform education, ensuring healthcare professionals and communities have the information they need at their fingertips.

Read the interview here: https://buff.ly/3WuXbtO