EpiCypher Inc.

EpiCypher Inc. EpiCypher is a bioscience company developing unique reagents and services for chromatin biology and epigenetics research.

A pioneer in the field of epigenetics and chromatin biology, EpiCypher is a bioscience company developing transformative technologies and delivering superior products to researchers world-wide. Our technologies and products are making studies possible that were not imaginable just a few years ago. Our innovation is a direct result of the scientific power associated with EpiCypher. Our renowned chromatin researchers possess expertise and unique insight into epigenetics that benefit our customers in ways other companies cannot. Arising from an abundance of demand for high quality products from the laboratories of Mark Bedford, Brian Strahl, and Or Gozani EpiCypher was founded on January 18, 2012 as a spin-out from University of North Carolina at Chapel Hill. Starting with the groundbreaking and proprietary histone peptide array platform, EpiGold™, EpiCypher has developed a wide portfolio of best in class products. EpiCypher's mission is to develop products to enable researchers to complete experiments that are not otherwise possible.

Join The Scientist for a live webinar featuring Andrew Stergachis, MD, PhD (University of Washington), the inventor of F...
09/23/2025

Join The Scientist for a live webinar featuring Andrew Stergachis, MD, PhD (University of Washington), the inventor of Fiber-seq. He will discuss how scientists are using Fiber-seq, a groundbreaking long-read sequencing approach, to pinpoint pathogenic noncoding variants and uncover their mechanistic roles in Mendelian disorders.

Resolving Mendelian Diseases with Long-Read Multiome Sequencing
📅 September 30 | 2:00 PM ET
🔗 Register here: https://www.the-scientist.com/resolving-mendelian-diseases-with-long-read-multiome-sequencing-73252

CUT&RUN and CUT&Tag are driving a new era in epigenomics.But data analysis shouldn't be the bottleneck.Join EpiCypher an...
09/22/2025

CUT&RUN and CUT&Tag are driving a new era in epigenomics.
But data analysis shouldn't be the bottleneck.

Join EpiCypher and DNAnexus on October 9 at 11am ET to explore how cloud-based tools can streamline your workflows. Spend less time troubleshooting pipelines and more time uncovering biology.

🔗 Register now: https://event.on24.com/wcc/r/5051158/51A2856CEB6CCBD1D77ED130D8CB806F?partnerref=dnanexus&utm_content=346220165&utm_medium=social&utm_source=linkedin&hss_channel=lcp-912957

🚨 Final deadline alert: EpiCypher 2025 registration closes tomorrow, September 22!If you’ve been waiting to sign up for ...
09/21/2025

🚨 Final deadline alert: EpiCypher 2025 registration closes tomorrow, September 22!

If you’ve been waiting to sign up for our flagship epigenetics conference, now’s the time. Join us in Cancún, Mexico from November 2–7 for a week of innovation, insight, and international scientific community.

🌴 Final seats are filling fast. Register today → https://www.epicypher.com/resources/epicypher-2025-conference/

❓ How do chromatin proteins regulate gene expression and protect against DNA damage?📢 A new study in Nucleic Acids Resea...
09/19/2025

❓ How do chromatin proteins regulate gene expression and protect against DNA damage?

📢 A new study in Nucleic Acids Research highlights how EpiCypher’s Captify™ platform and semi-synthetic nucleosomes were essential to dissect the interaction between PHRF1 and its histone target.

Key findings:
🧪 The PHD finger of PHRF1 specifically recognizes the unmodified N-terminus of histone H3
🧬 This interaction is required for proper DNA damage response
⚠️ A cancer-associated mutation (P221L) in PHRF1 disrupts binding and impairs genome integrity

This work expands our understanding of how PHD fingers influence chromatin dynamics, and how dysfunction contributes to human disease.

📄 Read the full paper: https://doi.org/10.1093/nar/gkaf666

📍 Brussels-bound for the Epigenetics and Epigenomics in Health and Disease conference?Join Dr. Michael-Christopher Keogh...
09/18/2025

📍 Brussels-bound for the Epigenetics and Epigenomics in Health and Disease conference?

Join Dr. Michael-Christopher Keogh, CSO of EpiCypher, for his talk on Sept 26 at 11:00 AM:

🧬 “The long and the short of it: multi-omic studies of chromatin function”

This presentation highlights how histone PTMs, TFs, nucleosome context, DNA methylation, and chromatin accessibility work together — and how multi-omic approaches are transforming our understanding of gene regulation in health and disease.

Happy International Online Learning Day! 🎓Whether you're refining your CUT&RUN workflow or exploring new DNA methylation...
09/15/2025

Happy International Online Learning Day! 🎓
Whether you're refining your CUT&RUN workflow or exploring new DNA methylation mapping strategies, we’ve got you covered.

Watch our latest webinars on demand:
🔬 Tips & Tricks for CUTANA™ CUT&RUN – Expert advice to get the most from your assay
🧬 Genome-Wide DNA Methylation Sequencing – How to achieve high coverage at lower cost using meCUT&RUN

🎥 Replay now:
▶ https://app.livestorm.co/epicypher/dna-methylation-sequencing

▶ https://app.livestorm.co/epicypher/unlock-chromatin-insights-with-cutana-cut-and-run

📣 EpiCypher CSO Dr. Michael-Christopher Keogh is presenting at Transcription and Chromatin UK 2025 on Sept 19 at 10 AM a...
09/11/2025

📣 EpiCypher CSO Dr. Michael-Christopher Keogh is presenting at Transcription and Chromatin UK 2025 on Sept 19 at 10 AM at The Midland Hotel, Manchester.

🎤 Talk: The long and the short of it: multi-omic studies of chromatin function

This session explores the coordinated roles of histone PTMs, nucleosome context, transcription factors, DNA methylation, and chromatin accessibility — and how new tools are enabling researchers to map these features together in multi-omic workflows.

A can’t-miss talk for anyone studying chromatin regulation.

We're excited to share that James Anderson from EpiCypher will speak at GenomeWeb’s Virtual Summit!📅 September 15 | ⏰ ~1...
09/10/2025

We're excited to share that James Anderson from EpiCypher will speak at GenomeWeb’s Virtual Summit!

📅 September 15 | ⏰ ~1:30 PM EDT
🎤 Catch his lightning talk right after the keynote in the session titled Epigenomics, Proteomics, Epistasis & Machine Learning.

This virtual summit brings together leading voices in multi-omics innovation. Make sure you're registered.
🔗 https://event.webcasts.com/starthere.jsp?ei=1729549&tp_key=d9887938ff

🚨 Live today at AGBT: Keith Maier presents Poster #507 from 4–5 PM PT!His work, “Standardizing Fiber-seq for Direct Mul...
09/09/2025

🚨 Live today at AGBT: Keith Maier presents Poster #507 from 4–5 PM PT!
His work, “Standardizing Fiber-seq for Direct Multi-omic Chromatin Profiling at Single-Molecule Resolution,” highlights a powerful method for direct, multi-modal mapping of epigenetic features.

📥 Download the full poster: https://explore.epicypher.com/posters/agbt-precision-health-2025/fiber-seq

📅 Mark your calendars: EpiCypher 2025 is heading to Cancún, Mexico, November 2 to 7!The registration deadline is now ext...
09/08/2025

📅 Mark your calendars: EpiCypher 2025 is heading to Cancún, Mexico, November 2 to 7!

The registration deadline is now extended to September 22, giving you more time to join the leading voices in chromatin and epigenetics research.

With sun, science, and next-gen workshops, this is a meeting you won’t want to miss.
🌊 Register today: https://www.epicypher.com/resources/epicypher-2025-conference/

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6 Davis Drive
Durham, NC
27709

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+18553742461

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