Viral Sign Inc.

08/23/2021

Are you responsible for caring for high risk individuals for COVID-19? Do you have a loved one in a senior care facility? Are you a school administrator? Is your production line at risk due to COVID-19? If so, we invite you to take 40 seconds to receive a quick overview of Viral Sign.

Viral Sign is advanced screening science designed to detect the presence of a virus prior to the expression of fever. Why is it important to identify individuals during the presymptomatic state? Influenza-like illnesses, and particularly COVID-19, are characterized by aggressive viral shedding prior to fever expression. As a result, identifying individuals while they are presymptomatic can be a life saver for the individual...a team...a work force...a population.

Viral Sign can be an important tool as part of a comprehensive effort to intercept the transmission of infectious disease in high risk settings. We invite you to reach out to us any time for an online demonstration of Viral Sign. You can request a demonstration by visiting us at viral-sign.com.

08/23/2021

When our journey began last year, we did not imagine we would see the launch of Viral Sign halfway around the world. Our focus was aimed at helping mitigate the transmission of infectious disease in the United States, with specific focus on settings where clinical risk is high due to the vulnerability of the population and/or operational risk requires keeping a work force healthy.

Of course, our ability to extend our reach is made possible by those clients who came alongside us early in the pandemic. Our clients are critical members of our extended team and it is their commitment to their patients, employees, athletes, and residents that motivates our efforts daily.

Many thanks also to the medical, research, and development teams at our partner, Thermofy. It is their shared commitment to leveraging insight and discovery that will shape the near- and long-term future of AI-enabled, infrared imaging solutions for medicine.

Finally, there is much work to do in India. The team is solid. We are fortunate to be working with dedicated partners. We are just getting started.

10/30/2020

Focus: The process of viral shedding and its relevance to effective screening for infectious disease.

The research paper, “Temporal dynamics in viral shedding and transmissibility of COVID-19”, presents the process of viral shedding across the presymptomatic and symptomatic phases. The researchers provide significant insight into the presymptomatic stage and the priority of identifying individuals who are infected prior to symptom expression. The ability to identify individuals prior to symptom onset is a key differentiator for Viral Sign.

Key findings from the paper:

- Presymptomatic, pre-elevated body temperature transmission represents at least 44% of viral transmissions, consistent with prior research with suggest the presymptomatic state may lead to as many as 58% of all transmissions of ILI.

- Viral transmission can begin as early as 12 days before elevated body temperature expression, but is highly unlikely this early in these disease process.
The greatest potential for virus transmission occurs in the presymptomatic state (three days prior to fever expression) and continues to the day of fever expression.

- Viral Shedding before and after symptom onset
Highlights from the authors:

“Assuming an incubation period distribution of mean 5.2 days from a separate study of early COVID-19 cases1, we inferred that infectiousness started from 12.3 days (95% CI, 5.9–17.0 days) before symptom onset and peaked at symptom onset (95% CI, –0.9–0.9 days) (Fig. 1c). We further observed that only

09/23/2020

It is hard to tell "who could be infecting who" in the picture below from the Wall Street Journal.

If you are a school system wrestling with the challenge of infectious disease screening for your staff and students, we will welcome the opportunity to explore delivering a non-contact, early-warning screening platform to your school. The screening science in Viral Sign is differentiated by the ability to identify the presence of virus, including COVID-19 and influenza, in individuals prior to the onset of fever. Call 833-99-VIRAL or visit us at our web site to leave your contact information.

Some reopened schools are taking children’s temperatures each day but experts and medical groups increasingly say a fever isn’t a good gauge of Covid-19.

09/11/2020

https://viral-sign.com/scientific-publications/research-article-from-science-magazine-reinforces-the-priority-of-identifying-individuals-while-presymptomatic-with-an-influenza-like-illness-including-covid-19/

“Transmission occurring rapidly and before symptoms, as we have found, implies that the epidemic is highly unlikely to be contained solely by isolating symptomatic individuals.”

09/11/2020

https://viral-sign.com/news/viral-sign-is-proud-to-sponsor-the-annual-meeting-of-the-american-academy-of-thermology-aat/

The American Academy of Thermology is the premiere organization in North America for the scientific development, healthcare training, and clinical application of medical infrared imaging.