Sage Integrative Medicine Clinic

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Edmonds, WA
Sage Integrative Medicine Clinic

Dr. Angila Jaeggli, owner of Sage Integrative Med offers family medicine, with the latest in nutritional, botanical and alternative medicine therapies.

Business and clinic of Dr. Angila Jaeggli, N.D., a family-practice naturopathic physician who practices in Edmonds, WA. Our clinic boasts several family-practice N.D.s, with an inhouse Quest Diagnostics Lab. We offer many specialty therapies, including: IV nutrient therapy, trigger point injections, IV and oral heavy metal chelation, bio-identical hormone therapy, specialty lab testing, craniosacral therapy, massage therapy, and PEMF pain therapy. We accept most forms of insurance. Come and visit today!

03/07/2026

GLP-1 stopped working like it used to? 😝 Let’s talk about receptor reset. 🔥😍

One of the most common questions I hear from patients on GLP-1 medications is:

“What happens when I reach the highest dose and it stops working as well?”

The reality is that our bodies adapt.
As GLP-1 medications are used over time, the cell receptors they act on can become less sensitive, which may lead to a plateau in weight loss or metabolic benefits.

In this video (Part 1 of a 3-part series), I explain why this happens and what we can do about it.

When patients approach maximum dosing, there are a few important strategies we consider:

✔️ Gradual dose adjustments – slowly increasing in small increments to find the lowest effective dose
✔️ Understanding medication tolerance – recognizing that receptor adaptation can occur over time

Then we start looking at ways to restore sensitivity.

Two strategies we discuss include:

1️⃣ Receptor Reset Therapy
Temporarily pausing the medication (often around 4–6 weeks) to allow the body’s receptors time to reset and become responsive again.

2️⃣ Regenerative Support Approaches
Emerging therapies using placental biologic extracts that contain cellular signaling factors. Research suggests these compounds may support cellular repair and communication pathways that influence receptor responsiveness.

This is a fascinating area of metabolic medicine and regenerative science that is evolving quickly.

✨ In the next videos I’ll cover:
Part 2: What a GLP-1 receptor reset actually looks like clinically
Part 3: How regenerative biologic therapies may support metabolic signaling

If you’re on a GLP-1 medication and feel like you’ve hit a plateau, there may be ways to strategically support your metabolism.

Stay tuned for Part 2.

— Dr. Angila

03/01/2026

If you’re on a GLP-1… your B vitamins matter more than you think. 😍🔥💉

As a physician who has worked with GLP-1 therapies for years, I can tell you this:

When you’re on medications like semaglutide or tirzepatide, your metabolism shifts.

You’re often:
• Moving into ketosis
• Increasing fat oxidation
• Burning through stored fuel
• Running your mitochondrial engines harder

And guess what fuels that engine?

👉 B vitamins.

B vitamins are required for:
✔️ Fat metabolism
✔️ Methylation
✔️ Mitochondrial energy production
✔️ Neurologic support
✔️ NAD production

When you increase metabolic demand, you increase B-vitamin utilization.

That means they can become depleted quickly.

Now layer on this:

Many people already struggle to absorb oral B vitamins well — especially if there’s any digestive compromise, low stomach acid, gut inflammation, or genetic methylation differences.

On a GLP-1? Absorption can be even more challenged.

This is why I often recommend:
• A methylated B-complex
• Or even better — injectable B complex through a compounding pharmacy prescribed by your physician

By bypassing the gut, we ensure absorption.

For many patients, I also consider:
• Injectable NAD support
• SS-31 peptide (mitochondrial support)
Because NAD and mitochondrial signaling are synergistic with metabolic therapies.

When you’re trying to optimize fat loss and metabolic health, we don’t just suppress appetite.

We support the cellular machinery doing the work.

That’s how you do this intelligently. 💛

As always — work with your physician and make sure your plan is personalized to you.

BComplex NAD LongevityMedicine

02/28/2026

Some mornings I’m tired. 😴 Some mornings I don’t want to go. You will never “feel like it” every morning. ( At least I don’t lol 😂) BUT! 👉 Your brain gets the message: We are a person who does hard things. 💪💪🏋️‍♀️

But here’s what I tell myself and my patients:

👉 The tiredness you feel when you wake up is often neurological — not physical.
👉 Within 5–10 minutes of movement, your cortisol rhythm aligns, dopamine rises, circulation improves.
👉 Blood sugar stabilizes.
👉 Inflammation begins to shift.
👉 Your brain gets the message: We are a person who does hard things.

Morning training isn’t just about calories or muscle.

It’s about:

• Rewiring your stress response
• Improving insulin sensitivity
• Building mitochondrial resilience
• Strengthening executive function
• Creating momentum before the world makes demands on you

When you train first, you stop negotiating with yourself all day.

You’ve already kept a promise.

And that changes how you show up.

Your future self is built in these quiet decisions.

– Dr. Angila 💪✨

BioOptimization SageStrong

02/22/2026

Morning yall!! 😍 Morning stack before I hit the weights that helps me show up strong and energized! 😁🔥

✔️ 20g protein
✔️ SLUPP 500mcg
✔️ Creatine 15g
✔️ L-Carnitine 1000mg
✔️ Injectable NAD 50mg
✔️ Injectable SS-31 1mg

Result?
Strong. Focused. Energized.
Crushed the workout with 5 minutes left on the clock. YES. 🔥

Stack smart. Train hard. Recover harder.

WomenWhoLift

02/06/2026

✨ Current obsession alert ✨ LOVE! 💕 When science, tech, and regenerative medicine really come together… this is what it looks like 😍

Lately, I’ve been absolutely loving this powerhouse combo:
⚡️ Juvasonic
⚡️ Potenza RF microneedling
⚡️ finished with KLOTHO topical peptide + Quantum Cell Factors

This trio is next-level for the face and neck—supporting healing, cellular renewal, and that healthy, radiant glow we’re all after. It’s powerful, elegant, and deeply regenerative… and yes, officially my new favorite combo.

When your treatments work with your biology, magic happens ✨

KlothoPeptide
LongevitySkin
IntegrativeAesthetics
DoctorApproved
GlowingSkin
FaceAndNeckRejuvenation

01/25/2026

Doctor hat off, lifting gloves on 👀💪 Sweat session was spicy today and I’m convinced my mitochondria were cheering 😂🔥
Movement is still one of my favorite prescriptions for mood, metabolism, and long-term vitality.
Bonus points for dancing between sets 🎧✨😁

A quick nerdy note for my fellow gym-lovers: SLU-PP-332 is being explored for its potential to support mitochondrial function, endurance, and metabolic efficiency. Early data looks interesting for performance and recovery enthusiasts, especially those of us 40+ who want to keep lifting, playing, and building strength. Nothing replaces smart training, nutrition, and rest, but I’m enjoying watching how this fits into the modern longevity + performance toolkit.

GymJoy LongevityVibes

12/06/2025

Industrious coaches are all amazing 🤩 and so incredible at guiding you and giving you options! 💪

Love, Olivia! 😍 She is incredible at encouraging you to push your limits! Which I love! ❤️🔥 But guide you safely!

If you’re new to CrossFit, or haven’t been in a while, or are looking for an awesome community to dial-in into and looking for CrossFit home, come join me here! This place is amazing, the community is amazing, we will fold you right in! 😁💪💗🥰

12/05/2025

😍You don’t have to live in pain. ✨
Whether it’s from arthritis, autoimmunity, old injuries, or the “I’ve-had-this-forever-and-just-learned-to-deal-with-it” kind of pain… your body is far more capable of healing than most people realize.

As an integrative + regenerative physician (and reminder: this is educational only, not medical advice 💛), I want you to know there are more options than what most patients are ever told.

🌱 Regenerative therapies aren’t just the future — they’re here. And many of them are accessible, gentle, and designed to support your body’s own repair systems. Some of the most powerful tools include:

💠 Healing peptides that support tissue repair and inflammation regulation
💠 Biologic therapies that help activate your natural healing responses
💠 Oxygen-based therapies that enhance cellular recovery
💠 IV vitamin therapies that create a nutrient-rich foundation for regeneration and resilience
💠 And many emerging free or low-cost practices that help your nervous system and immune system reset 🧠✨

Pain is not your identity.
Pain is not your destiny.
And you’re allowed to explore options that move you toward freedom, strength, and actual healing — not just coping.

If you’ve been feeling stuck, unheard, or told “this is just how it is”… there is another path. And it’s never too late to begin healing.

💛 Again, this content is for education only and not medical advice. Always talk with your healthcare provider about what’s right for you.

12/04/2025

Hitting 100–120 g of protein a day is one of the most underrated tools for building and maintaining muscle — especially during weight loss.
(And yes… I’m a physician, but this is not medical advice — just education 🤍)

Here’s why I recommend a higher-protein day for most of my patients and anyone working on strength + body composition:

💪 Protects Your Muscle
When you’re losing weight, your body can break down muscle along with fat. Protein helps preserve lean mass so your metabolism stays strong.

🔥 Keeps You Fuller, Longer
Protein stabilizes appetite, reduces cravings, and helps you feel satisfied without the spikes and dips.

⚡ Supports Muscle Growth
If you lift, do Pilates, CrossFit, or any resistance training, your muscles need amino acids to repair and grow.

✨ Slight Metabolic Boost
Protein has the highest thermic effect of all macros — meaning you burn a little more just digesting it.

🥚 So Many Easy Options
Protein waters
Protein-fortified pasta
Greek yogurt, cottage cheese
Meat, eggs, fish, tofu
Protein cold foam at Starbucks (yes, it counts 😏)
And of course, quality protein powders

📌 General goal:
Aim for 25–35 g per meal, then fill the gaps with snacks or shakes to hit your daily target.

Your muscle is metabolic gold — protect it. 💛

12/02/2025

Tesofensine: The Hidden Metabolic Powerhouse 🔥🧠

If you’ve never heard of tesofensine, you’re not alone — but it’s one of the most promising metabolic tools we have right now.

Originally researched for neurological conditions, researchers quickly realized something interesting… patients were losing weight fast and reporting better energy, sharper focus, and reduced cravings. 👀

So what does it actually do?

✨ Crushes appetite (works on dopamine, norepinephrine + serotonin)
✨ Boosts metabolic rate
✨ Improves energy + motivation
✨ Supports insulin sensitivity + blood sugar control
✨ Helps reduce visceral fat

In clinical trials, patients lost 10–12% of their bodyweight in just 24 weeks — without injections.

This isn’t an amphetamine.
This isn’t a GLP-1.
It’s a unique triple-pathway approach that helps you stay full, focused, and in control.

Side notes:
• Start low (0.25 mg)
• Avoid late dosing (hello insomnia)
• Not for uncontrolled BP or arrhythmias
• Pair with strength training + high protein 💪

11/29/2025

My science-backed pre-workout stack that keeps me strong, sharp, and injury-resistant — in the gym AND in mom-life.

✨ My Pre-Workout Science:
Creatine (15g): Most women underdose it — creatine boosts phosphocreatine stores → faster ATP regeneration → more power + better recovery.
Caffeine: My focus switch. Increases reaction time, mental drive, and lowers perceived effort. Translation: heavy lifts feel lighter.
Collagen (20g): Glycine + proline help support tendon + ligament strength. Consistent intake = better connective tissue repair.

Strong moms use science. 🧬💪✨

11/22/2025

Crushing Saturday workouts with my go-to pre-game stack 💪✨

Here’s what’s powering me today:

⚡️ 20g Creatine
✨ 20g Collagen
🔋 NAD
🔷 Methylene Blue
💦 Electrolytes

Feeling strong, focused, and ready to take on ALL the intervals.
Your reminder that fueling your body is just as important as showing up. Let’s get after it! 😁🔥💪

⸻

Education only, not medical advice.

Address

110 James Street
Edmonds, WA
98020

Website

http://www.sagemedclinic.com/

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