Bolus Med Spa

Bolus Med Spa Aesthetic & Laser Medicine

11/04/2025

🚨 GLP-1s & Your BOTOX: What the New Study Says and why your treatment may not last as long💉

If you’re taking a GLP-1 receptor agonist (like Ozempic, Mounjaro, or Wegovy) and also get type A neurotoxin like Botox, you need to see this! A new computational study suggests that GLP-1 medications may reduce the durability of your botulinum toxin treatments.

Here are the key statistics from the computational model:
* Chronic Migraine Treatment: The mean duration of effect for BoNT-A (Botox) declined from 14.0 weeks (in controls) to as low as 11.8 weeks in patients with high GLP-1 exposure.
* Aesthetic Treatments (Masseter Prominence): The mean duration of effect decreased from 20.1 weeks (in controls) to a minimum of 16.2 weeks.
* Drug Hierarchy: The study suggested the effect varied by drug, with the greatest reduction in duration modeled for tirzepatide (Mounjaro/Zepbound), followed by liraglutide, then dulaglutide, and finally semaglutide (Ozempic/Wegovy).

* The Cause: The reduction in durability was attributed primarily to synaptic modulation (~55%)—the drug’s effect on nerve signaling—and lean-mass decline (~30%).

The Bottom Line: If you’re on a GLP-1, you may need to schedule your Botox touch-ups sooner than before. While not specifically implied, this would include compounded medications as well.

⚠️ Always consult your healthcare provider and injector to discuss any medications you are taking and to tailor your treatment plan!

The Study and Link:
* Title: Computational modelling the impact of GLP-1 receptor agonists on botulinum toxin A: Evidence for reduced treatment durability across neurologic and aesthetic indications
* Link (PubMed): Computational modelling the impact of GLP-1 receptor agonists on botulinum toxin A

10/20/2025
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Understanding the signals your body sends is the first step to unlocking a supercharged life! From unexplained weight gain to fatigue, recognizing thyroid dysfunction can be tricky. But here at our wellness center in Columbia, Maryland, we're dedicated to providing you with the guidance you need to explore thyroid optimization. From diet tips to stress management techniques, let's embark on this journey to enhanced well-being together!

Full Thyroid discussion on our blog. Link in bio.

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This July, we also emphasize skin health awareness and offer exclusive products like the SunBetter Tone Smart SPF 75 with the purchase of our Mystro Active Balance Serum. Join us in promoting skin safety and wellness.

https://conta.cc/40GfSNc

Email from Bolus Med Spa, INC New Features are Live! Explore Jane and Book Your Next Appointment Easily.       INTRODUCING JANE: OUR NEW ELECTRONIC HEALTH RECORD   ---------> CLICK HERE TO BOOK APPOIN

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So why does breast cancer increase after menopause?⭐️Many reasons, but one of the main protective hormones you have in y...
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So why does breast cancer increase after menopause?
⭐️Many reasons, but one of the main protective hormones you have in your body is estrogen.

Once you go through menopause, your estrogen level drops to almost 0, leaving you vulnerable without the long-term protective benefits.
This is where breast cancer rates increase, osteoporosis start s showing up along with Alzheimer’s, dementia, and so many other problems.

Historically estrogen replacement has been viewed as bad or harmful. What’s harmful is giving the synthetic version or the wrong form of the bioidentical version.

Your body makes estrogen. Some providers will prescribe synthetic estrogen when you hit perimenopause or menopause. But in fact, this can harmful. What you should be demanding is ESTRADIOL!!

That is not harmful in any way, shape or form. But to take it one step further, the delivery method is also just as important. If you’re getting a topical cream, that’s more than likely a synthetic estrogen and won’t give you those long-term health benefits.

Now, it will help with your moodiness or hot flashes, symptoms related to perimenopause, but it won’t give you the bigger, long-term benefits or protective benefits from breast/endometrial cancer, Alzheimer’s/dementia, osteoporosis, cardiovascular disease, stroke, or heart attack.

⭐️It’s important to know what you’re getting. ⭐️It’s important to get the right form of this medication. ⭐️It’s important to get the right delivery method. ⭐️It’s important to know what your level is. If you don’t know what your level is, then you risk missing all of the protective benefits.

To learn more about your level or chat about BHRT, book a free virtual consultation on our website!!

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7310 Esquire Court
Elkridge, MD
21075

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Men and women have different needs when it comes to taking care of their bodies. In spite of the differences, we all share one common goal: to live a happy, healthy life.

This is why Bolus Med Spa exists, being Columbia's only IV Hydration bar. With our premium of hydration, vitamin, and aesthetics services, we want nothing more than to help our clients look and feel their best. We want our clients to feel energized, be confidently beautiful, active, and healthy in whatever they do.

Schedule an appointment and visit us! Experience comfort and wonders the moment you step into our office. We cannot wait to see you!