St. Mary's Regional Medical Center

St. Mary's Regional Medical Center St. Mary’s Regional Medical Center is a 229-bed acute care facility located in Enid, Oklahoma. Mary’s Regional Medical Center is located in Enid, Oklahoma.

The hospital has 229 licensed beds and offers a comprehensive range of inpatient and outpatient services. Areas of specialization include cardiac services, neurosciences, orthopedics, women's health, emergency medicine and rehabilitation. Social media accounts are managed by Marketing. We are unable to provide medical advice through social media. Please contact your physician, or in case of emergency, call 911. Although we do our best to respond to comments and messages, there may be a delay in response time, and we may not be able to respond due to the nature of the message. Please visit our website for language assistance, disability accommodations, the non-discrimination notice, Terms of Service and other important disclaimers.

St. Mary’s Volunteer Food Drive: We are thrilled to announce that the St. Mary’s Volunteers, with amazing support from S...
11/14/2025

St. Mary’s Volunteer Food Drive: We are thrilled to announce that the St. Mary’s Volunteers, with amazing support from St. Mary’s staff, collected and donated 212 pounds of food to our local food bank, Loaves and Fishes. Your generosity filled bags, boxes and trunks with essentials — cereal, canned goods, toiletries and more. It will make a real difference for neighbors facing food insecurity.

A huge thank you to every volunteer, staff member and donor who made this possible. Your time, energy and donations turned a simple idea into a powerful show of community care. ❤️

🌟 Employee of the Month – November 🌟We are thrilled to announce that Kelley Hayes has been named our November Employee o...
11/13/2025

🌟 Employee of the Month – November 🌟

We are thrilled to announce that Kelley Hayes has been named our November Employee of the Month!

Kelley embodies the very best of teamwork, compassion and dedication. She consistently goes above and beyond to support her coworkers, ensure patient safety and create a welcoming environment for everyone she encounters. Whether it’s keeping things running smoothly behind the scenes, stepping in to help during busy shifts, or greeting patients and colleagues with her trademark smile, Kelley makes a lasting impact every single day.

Her positivity, hard work and selfless commitment shine through in everything she does, and we are so grateful to have her as part of our St. Mary's team.

Please join us in congratulating Kelley on this well-deserved recognition!

Honoring Our Veterans — Today and Every DayAs we look ahead to Veterans Day tomorrow, St. Mary’s Regional Medical Center...
11/10/2025

Honoring Our Veterans — Today and Every Day

As we look ahead to Veterans Day tomorrow, St. Mary’s Regional Medical Center is honored to have joined our community this past weekend in celebrating those who served. ❤️🤍💙

A special thank you to the Enid OK Air Force Association (AFA) Chapter 214 for hosting a wonderful Veterans Day presence at the Enid courthouse lawn during Saturday’s parade and for giving our community a chance to connect and honor our local heroes together.

We were proud to support the event by providing refreshments for parade-goers and participants, a small way to share warmth and gratitude with those who give so much. To all veterans and their families, we thank you for your courage, your service and your sacrifice. You are the heart of our community. ❤️

When someone suddenly collapses or feels seriously unwell, it can be hard to tell what’s going on—especially in hot weat...
11/06/2025

When someone suddenly collapses or feels seriously unwell, it can be hard to tell what’s going on—especially in hot weather. Knowing the difference could save your life or someone else’s.

Lior Shamai, DO, a cardiologist with St. Mary’s Regional Medical Center, discusses the differences between a heart attack and heat stroke and what to look out for.

When someone suddenly collapses or feels seriously unwell, it can be hard to tell what’s going on—especially in hot weather.

11/01/2025

🕰️ Time to Fall Back! 🍂

Don’t forget to set your clocks back one hour this Sunday, November 2nd, at 2:00 a.m. as Daylight Saving Time ends.

That’s a wrap! 🎵 🎤 The St. Mary’s internal United Way campaign is coming to a close, but not before a final round of exe...
10/30/2025

That’s a wrap! 🎵 🎤 The St. Mary’s internal United Way campaign is coming to a close, but not before a final round of executive suite lip-sync entertainment.

The festivities included a Blues Brothers-style rendition of “Ain’t No Mountain High Enough,” followed by a “Color the Stache” pledge. Thank you to all our staff who participated in the fun events hosted by our United Way Campaign Committee. From raffles to Taco Tuesday and beyond, we raised a significant amount of money to give back to our community.

We’re proud to work alongside some of the most generous employees in northwest Oklahoma. Thank you for all you do for our patients and the communities we serve. In total, our employees raised/donated $27,000 to the United Way of Enid & NW Oklahoma.

🍂 This morning, the St. Mary’s Rehab Institute team brought the warmth (and the sweets!) with their Annual Fall Bake Sal...
10/29/2025

🍂 This morning, the St. Mary’s Rehab Institute team brought the warmth (and the sweets!) with their Annual Fall Bake Sale in support of the Salvation Army’s “Spruce Up a Life” program.

From homemade goodies to generous hearts, our staff showed up strong for a cause that means so much. 💛

St. Mary’s Casts a Spell at the United Way Chili Cook-Off! 🌶️On Friday, the St. Mary’s team attended the United Way Chil...
10/28/2025

St. Mary’s Casts a Spell at the United Way Chili Cook-Off! 🌶️

On Friday, the St. Mary’s team attended the United Way Chili Cook-Off, dazzling the crowd with a magical booth.

Mary Jo, interim dietary director, brewed up a chili so good it had everyone enchanted. Guests voted with donations to support the United Way of Enid & NW Oklahoma.

From spooky booths to warm community spirit, the event was pure magic.

🎉👏 Congratulations, Keagan and Jason! 👏🎉IS Director Tracy is celebrating with two awesome members of our Information Ser...
10/27/2025

🎉👏 Congratulations, Keagan and Jason! 👏🎉

IS Director Tracy is celebrating with two awesome members of our Information Services team on their well-deserved promotions! Your hard work, dedication and tech know-how keep things running smoothly behind the scenes. We’re so lucky to have you on the team. Enjoy those sweet treats!

🎉 Happy Pharmacy Week! 🎉 We’re celebrating our amazing Pharmacy team for all they do every day to keep our patients safe...
10/23/2025

🎉 Happy Pharmacy Week! 🎉

We’re celebrating our amazing Pharmacy team for all they do every day to keep our patients safe and cared for! From managing medications to answering questions and supporting clinical teams, they play a vital role in every department of the hospital (and always with a smile)! Thanks for bringing your knowledge, teamwork and good vibes every single day. We appreciate you more than words can say! 💙

🎀 October is Breast Cancer Awareness Month 🎀Breast cancer is the most common cancer diagnosed in women in the U.S., asid...
10/21/2025

🎀 October is Breast Cancer Awareness Month 🎀

Breast cancer is the most common cancer diagnosed in women in the U.S., aside from skin cancers. Early detection saves lives — regular mammograms and knowing what’s normal for your body are key.

Let’s raise awareness, support those affected and encourage proactive care. 💗

🎉 This week, we’re celebrating Case Management Week at St. Mary’s!Our incredible case managers are the heart of patient ...
10/15/2025

🎉 This week, we’re celebrating Case Management Week at St. Mary’s!

Our incredible case managers are the heart of patient advocacy—connecting individuals and families with the care, services and support they need to thrive. 💙

Thank you to our dedicated team for making a difference every day. We appreciate you!

Address

305 S 5th Street
Enid, OK
73701

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Our Story

St. Mary's Regional Medical Center in Enid, Oklahoma was founded in 1915 by Dr. G.A. Boyle as a 12-bed hospital named Enid Spring Sanatorium and Baths. The hospital was purchased in 1937 by the Adorers of the Blood of Christ of Wichita, Kansas and was leased by Hospital Corporation of America (HCA) from 1984 to 1995. The Sisters of Mercy Health System, St. Louis, Missouri, purchased the hospital in 1995 and made it a part of the Mercy Health System Oklahoma.

Physicians are independent practitioners who are not employees or agents of this hospital. The hospital shall not be liable for actions or treatments provided by physicians. For language assistance, disability accommodations and the non-discrimination notice, visit our website. Hospital social media accounts are managed by the hospital marketing team. We are unable to provide medical advice through social media. Please contact your physician, or in case of emergency, call 911. Although we do our best to respond to comments and messages, there may be a delay in response time, and we may not be able to respond due to the nature of the message. Thank you.